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UPENN || SOM || Center for Clinical Immunology || Faculty
Faculty
- Roberto Caricchio, MD - email
- Research Interest: Relevance of cell death in sustaining lupus auto-immunity
- Andrew Caton, PhD - email
- Research Interest: Cellular and molecular basis for immune repertoire formation, mechanisms of T and B cell tolerance, regulatory T cells, autoimmune disease
- Kyong-Mi Chang, MD - email
- Research interest:Immune mechanisms of viral persistence and liver disease progression in patients infected with hepatitis C
- Youhai Chen, MD, PhD - email
- Research Interest: Autoimmunity, apoptosis and gene therapy
- Douglas B. Cines, MD - email
- Research Interest:
Autoimmune hematologic conditions including the pathogenesis and of ITP, TTP and HIT.
- Naom Cohen, MD, PhD - email
- Research Interest: Alterations of the sinus mucosal function in chronic rhinosinusitis (CRS); Role of bacterial biofilms in the etiology and progression of CRS; topical therapeutic interventions in the management of CRS.
- Philip L. Cohen, MD - email, website
- Research Interest: Systemic autoimmunity, murine models of SLE and Sjogren's disease
- Randy Q. Cron, MD, PhD - email
- Research Interest:
Transcriptional regulation of cytokine genes and HIV-1 in primary CD4 T lymphocytes.
- Alden Doyle, MD - email
- Research Interest:
Kidney transplantation with focus on immunosuppression and the chronic kidney disease (CKD) that develops after nonrenal transplantation.
- Joseph Dalmau, MD, PhD - email
- Research Interest: Effects of cancer on the nervous system mediated by immunological mechanisms
- Robert Eisenberg, MD - email
- Research Interest: Immunoregulation of systemic autoimmunity, in mice and in humans, particularly as regards the role of B cells in SLE.
- Jan Erikson, PhD - email
- Research Interest:
Regulation of self-reactive B cells and T cells in host defense, autoimmunity, and cancer
- Terri Finkel, MD, PhD - email
- Research Interest:
Molecular mechanisms of lymphocyte activation in health and disease, with an emphasis on mechanisms of viral persistence and immune dysregulation.
- Mark Green, MD, PhD - email
- Research Interest:
FOXP3 ensembles in T cell regulation; erbB system- molecular mechanisms of tumor progression and immune targeted therapy
- Angel Haczku, MD, PhD - email
- Research Interest: Animal Models of chronic inflammatory airway diseases with focus on asthma and chronic obstructive lung disease.
- Wayne Hancock, MD, PhD - email
- Research Interest:
Use of animal models to analyze the mechanisms of allograft rejection and tolerance, and any insights attained are further refined through non-human primate and clinical studies.
- Carl H. June, MD - email
- Research Interest: Immunotherapy for cancer; mechanisms of lymphocyte activation;therapeutic immunization strategies for patients with cancer
- Malek Kamoun, MD, PhD - email
- Research Interest:
Immunogenetics and immunobiology of transplantation.
- Gary Koretzky, MD, PhD
- email
- Research Interest:
Signal transduction events important for hematopoietic cell development and function.
- Arnold I. Levinson, MD - email
- Research Interest: Cellular and molecular basis of autoimmune and immunodeficiency disease
- Eline Luning-Prak, MD, PhD - email
- Research Interest: Regulation of antibody gene rearrangement (receptor editing) and repertoire formation in B cells of healthy and autoimmune-prone individuals.
- James Markmann, MD, PhD - email
- Research Interest:
Developing strategies to induce transplantation tolerance for application to clinical pancreatic islet transplantation.
- Dimitrios Monos, PhD - email
- Research Interest:
Structure-Function of Histocompatibility Molecules and their role in Transplantation and Diseases.
- John G. Monroe, PhD
- email
- Research Interest:
Lymphocyte development; antigen receptor signal transduction; epithelial cell cancer
- Jordan Orange, MD, PhD - email
- Research Interest:
Stages in formation and function of the natural killer cell immunological synapse, and primary immunodeficiency diseases.
- Yvonne Patterson , MD, PhD - email
- Research Interest:
Immunotherapeutic approaches targeting tumor cells.
- Elena Perez, MD, PhD - email
- Research Interest:Gene therapies for primary immunodeficiencies.
- Ellen Pure, PhD - email
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- Research Interest: Regulation of infiltrating leukocytes by modified ECM components, contact with parenchymal cells and by cytokines using in vitro and in vivo in murine models of atherosclerosis.
- James L. Riley, PhD - email
- Research Interest:
Developing adoptive T cell therapies for cancer and HIV as well as developing the primary human T cell as an experimental model.
- Alain Rook, MD - email
- Research Interest: Immunotherapeutic approaches to cutaneous T-cell lymphoma including 1) the development of novel immunomodulatory agents for therapy; elucidation of mechanisms of action of new therapeutic agents; mechanisms for the endogenous immunosuppression caused by the malignant T-cells in CTCL
- Myrna R. Rosenfeld, MD, PhD - email
- Research Interest:
Identifying novel agents for the treatment of malignant glial tumors
- Philip A. Scott, PhD - email
- Research Interest:
Development of Th1 effector and memory T cells
- Donald L. Siegel, MD, PhD - email
- Research Interest:
molecular methods (antibody phage display) to clone and characterize human monoclonal antibodies responsible for autoimmune disease (e.g. ITP, TTP, pemphigus, HIT) and alloimmune responses in the setting of hemolytic transfusion reactions and hemolytic disease of the newborn.
- Jonathan Spergel, MD, PhD - email
- Research Interest:
Immune mechanism responsible for the progression of atopic dermatitis to asthma.
- Kathleen Sullivan, MD, PhD
- email
- Research Interest:
Epigenetic regulation of inflammatory cytokines.
- Craig B. Thompson, MD - email
- Research Interest: Biochemical mechanisms that promote cell survival,and regulate cell growth, proliferation, lymphocyte homeostatis, and neoplastic transformation
- Laurence A. Turka, MD - email, website
- Research Interest:
T cell tolerance, with particular focus on transplantation and autoimmunity.
- Mark L. Tykocinski, MD - email
- Research Interest:
Design of novel fusion proteins with immunotherapeutic potential
- Robert H. Vonderheide, MD, DPhil
- email
- Research Interest:
Tumor immunology and immunotherapy
- Joan M. Von Feldt, MD - email
- Research Interest: Premature atherosclerotic disease in Systemic Lupus Erythematosus (SLE).
- David Weiner, PhD - email
- Research Interest: DNA vaccines for infectious diseases and immune therapy of cancer.
- Andrew Wells, PhD - email
- Research Interest: Molecular mechanisms of peripheral T lymphocyte tolerance.
- Victoria P. Werth, MD - email
- Research Interest: Effect of ultraviolet light on skin; cultaneous autoimmune disease, including lupus, pemphigus, and dermatomyositis
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