Open to Enrollment
- HIV Comorbidities (CMV, Hepatitis B, Weight Gain)
- HIV Cure Related
- HIV New Therapies (long-acting medications, switch to new treatment)
- HIV Women's Health (pregnancy, breastfeeding)
- Vaccines
HIV Comorbidities (CMV, Hepatitis B, Weight Gain)
A5394 Safety, Tolerability, and Impact of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants with Both Chronic Hepatitis B and HIV. Jason Kirschner
HIV Cure Related
A5374 A Phase I/IIa Randomized, Placebo-Controlled Trial of Conserved-Mosaic T-cell Vaccine in a Regimen with Vesatolimod and Broadly Neutralizing Antibodies in Adults Initiated on Suppressive Antiretroviral Therapy during Acute HIV-1. Safa Elbakhit
A5388 A Double-Blind, Randomized, Placebo-Controlled Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined with ART Initiation during Acute HIV Infection to Induce HIV Remission. Tina Nguyen
HIV New Therapies (long-acting medications, switch to new treatment)
Gilead 6143 Phase 1b Randomized, Blinded, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of GS-8588 in People with HIV-1 who are Virologically Suppressed on Antiretroviral Therapy. Jason Kirschner
CROWN A Phase 3b, Open Label, Randomized, Standard-of-Care Control Arm, Multicenter, Superiority Study Evaluating the Efficacy, Safety and Tolerability of Injectable CAB LA + RPV LA in Viremic Participants living with HIV-1. Tina Nguyen
HIV Women's Health (pregnancy, breastfeeding)
GS-985-6381 Economic Incentive to Increase Provider Reporting to the Antiretroviral Pregnancy Registry. Erin Logue-Chamberlain
Vaccines
BNT163-01 Phase 1, Randomized, Observer-blinded, Placebo-controlled, 2-part, Dose Escalation and Expended Safety Evaluation Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Prophylactic Vaccine for the Prevention of Genital Lesions Caused by HSV-2 and Potentially HSV-1. Chungdhak Tsang
A5422 Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living with HIV-1 on Suppressive Antiretroviral Therapy. Safa Elbakhit