Associate ProfessorView Lab Website
726 Clinical Research Building
415 Curie Boulevard
Philadelphia, PA 19104
The Prosser Lab - developing new therapies for the heart and brain.
Our lab interrogates the forces of the heart – the mechanisms that control how a heart cell generates force, and how force itself feeds back to regulate cell function and form. We leverage cellular biophysics and engineering, super-resolution imaging and cardiology to tackle the fundamental challenges of the mechanobiology of the heart. Our goal is to provide transformative insight into how the heart beats, and to inform new therapies for the treatment of heart disease.
The diagnosis of Dr. Prosser's daughter with STXBP1 encephalopathy also spurred the generation of a new therapeutic arm in the lab for neurological applications. We are developing novel, antisense oligonucleotide based therapies for the treatment of inherited neurodevelopmental disorders, such as those caused by mutations in STXBP1.
BS, Wake Forest University, 2005
PhD, University of Maryland School of Medicine, 2009
2011 Outstanding Postdoctoral Scholar Award
2017 Linda Pechenik Montague Investigator Award
2017 Outstanding Early Career Investigator Award, American Heart Association (AHA)
2018 Outstanding Alumnus Award, University of Maryland School of Medicine
2021 Lead Coordinator, Leducq Transatlantic Network of Excellence
Pennsylvania Muscle Institute
Cardiac Muscle Society
American Heart Association
STXBP1 Foundation Scientific Advisory Board