November 9, 2021
AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signaling to govern muscle physiology
Tejvir Khurana, Paul Titchenell, Ph.D.
Natasha Jaiswal, Matthew Gavin, Emanuele Loro, Jaimarie Sostre-Colón, Paul A. Roberson, Kahealani Uehara, Nicole Rivera-Fuentes, Michael Neinast, Zoltan Arany, Scot R. Kimball, Tejvir S. Khurana, Paul M. Titchenell https://doi.org/10.1002/jcsm.12846
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November 3, 2021
Truncated titin proteins in dilated cardiomyopathy
Kenneth B. Margulies, M.D., Benjamin Prosser, Ph.D.
QUENTIN MCAFEE, CHRISTINA YINGXIAN CHEN, YIFAN YANG, MATTHEW A. CAPORIZZO, MICHAEL MORLEY, APOORVA BABU, SUNHYE JEONG, JEFFREY BRANDIMARTO, KENNETH C. BEDIJR, EMILY FLAM, JOSEPH CESARE, THOMAS P. CAPPOLA, KENNETH MARGULIES, BENJAMIN PROSSER AND ZOLT ARANY/ DOI: 10.1126/scitranslmed.abd7287
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October 27, 2021
Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal dendrites
Melike Lakadamyali, Ph.D., Erika Holzbaur, Ph.D., Michael Ostap, Ph.D.
Masucci EM, Relich PK, Lakadamyali M, Ostap EM, Holzbaur ELF.Mol Biol Cell. 2021 Oct 27:mbcE21100480. doi: 10.1091/mbc.E21-10-0480. Online ahead of print. PMID: 34705476
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October 24, 2021
Inhibition of Peroxiredoxin 6 PLA2 Activity Decreases Oxidative Stress and the Severity of Acute Lung Injury in the Mouse Cecal Ligation and Puncture Model
Shampa Chatterjee, Ph.D.
Fisher AB, Dodia C, Tao JQ, Feinstein SI, Chatterjee S. Antioxidants (Basel). 2021 Oct 24;10(11):1676. doi: 10.3390/antiox10111676. PMID: 34829547; PMCID: PMC8615065.
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October 15, 2021
Ribosome Elongation Kinetics of Consecutively Charged Residues Are Coupled to Electrostatic Force
Carol Deutsch, Ph.D.
Sarah E. Leininger, Judith Rodriguez, Quyen V. Vu, Yang Jiang, Mai Suan Li, Carol Deutsch, and Edward P. O’Brien. Biochemistry 2021 60 (43, 3223-3235. ) DOI: 10.1021/acs.biochem.1c00507
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September 10, 2021
Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy
Erika Holzbaur, Ph.D.
Strong LM, Chang C, Riley JF, Boecker CA, Flower TG, Buffalo CZ, Ren X, Stavoe AK, Holzbaur EL, Hurley JH. Elife. 2021 Sep 10;10:e70372. doi: 10.7554/eLife.70372.PMID: 34505572
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August 15, 2021
Utility of FDG PET/CT in assessing bowel inflammation
Shampa Chatterjee, Ph.D.
Gelston D, Brosler SC, Vazquez J, Sorci O, Griffith AH, Chatterjee S, Buchner A, Høilund-Carlsen PF, Alavi A, Rajapakse CS. Am J Nucl Med Mol Imaging. 2021 Aug 15;11(4):271-279. PMID: 34513280; PMCID: PMC8414397.
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August 6, 2021
Vascular Health: The Endothelial Perspective in Regulation of Inflammation and Injury
Shampa Chatterjee, Ph.D.
Chatterjee S, Lacchini S, Jungraithmayr W, Wehrli FW. Front Physiol. 2021 Aug 6;12:732234. doi: 10.3389/fphys.2021.732234. PMID: 34426732; PMCID: PMC8379013.
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June 15, 2021
ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy
Erika Holzbaur, Ph.D.
Harding O, Evans CS, Ye J, Cheung J, Maniatis T, Holzbaur ELF. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2025053118. doi: 10.1073/pnas.2025053118. PMID: 34099552
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May 24, 2021
Cytoskeletal regulation guides neuronal trafficking to effectively supply the synapse
Erika Holzbaur, Ph.D.
Aiken J, Holzbaur ELF.Curr Biol. 2021 May 24;31(10):R633-R650. doi: 10.1016/j.cub.2021.02.024.PMID: 34033795 Review.
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