TBC1D30 regulates proinsulin and insulin secretion and is the target of a genomic association signal for proinsulin
Damaris Lorenzo
Parsons VA, Vadlamudi S, Voos KM, Rohy AE, Moxley AH, Cannon ME, Rosen JD, Mills CA, Herring LE, Broadaway KA, Lorenzo DN, Mohlke KL. Diabetologia. 2025 Mar 10. doi: 10.1007/s00125-025-06391-w. Online ahead of print. PMID: 40064677
Epigenome-wide association study for dilated cardiomyopathy in left ventricular heart tissue identifies putative gene sets associated with cardiac pathology and early indicators of cardiac risk
Kenneth B. Margulies, M.D.
Tan K, Tay D, Tan W, Ng HK, Wong E, Morley MP, Singhera GK, Lee CJM, Jain PR, Tai FL, Hanson PJ, Cappola TP, Margulies KB, Foo R, Loh M. Clin Epigenetics. 2025 Mar 8;17(1):45. doi: 10.1186/s13148-025-01854-8. PMID: 40057770
Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer
Robert J. Lee, Ph.D
Wei K, Hill BL, Thompson JC, Miller ZA, Mueller A, Lee RJ, Carey RM. Head Neck. 2025 Mar 5;. doi: 10.1002/hed.28120. [Epub ahead of print] PubMed PMID: 40040415; NIHMSID:NIHMS2059808.
Lactate homeostasis is maintained through regulation of glycolysis and lipolysis
Joseph A. Baur, Ph.D.
Lee WD, Weilandt DR, Liang L, MacArthur MR, Jaiswal N, Ong O, Mann CG, Chu Q, Hunter CJ, Ryseck RP, Lu W, Oschmann AM, Cowan AJ, TeSlaa TA, Bartman CR, Jang C, Baur JA, Titchenell PM, Rabinowitz JD. Cell Metab. 2025 Mar 4;37(3):758-771.e8. doi: 10.1016/j.cmet.2024.12.009. Epub 2025 Jan 30. PubMed PMID: 39889702; PubMed Central PMCID: PMC11926601.
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