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May 4, 2022
Cysteine-Based Mimic of Arginylation Reproduces Neuroprotective Effects of the Authentic Post-Translational Modification on α-Synuclein
Pan B, Shimogawa M, Zhao J, Rhoades E, Kashina A, Petersson EJ.
DOI: 10.1021/jacs.2c02499
Article
May 2, 2022
Acute Deletion of the FOXO1-dependent Hepatokine FGF21 Does not Alter Basal Glucose Homeostasis or Lipolysis in Mice
Sostre-Colón J, Gavin MJ, Santoleri D, Titchenell PM.
DOI: 10.1210/endocr/bqac035
Article
April 28, 2022
Structural insights into TRPV2 activation by small molecules
Pumroy RA, Protopopova AD, Fricke TC, Lange IU, Haug FM, Nguyen PT, Gallo PN, Sousa BB, Bernardes GJL, Yarov-Yarovoy V, Leffler A, Moiseenkova-Bell VY.
DOI: 10.1038/s41467-022-30083-3
Article
April 26, 2022
Structural basis of TRPV5 regulation by physiological and pathophysiological modulators
Fluck EC, Yazici AT, Rohacs T, Moiseenkova-Bell VY.
DOI: 10.1016/j.celrep.2022.110737
Article
April 19, 2022
The microtubule cytoskeleton in cardiac mechanics and heart failure
Caporizzo MA, Prosser BL.
DOI: 10.1038/s41569-022-00692-y
Article
April 16, 2022
T2R bitter taste receptors regulate apoptosis and may be associated with survival in head and neck squamous cell carcinoma
Carey RM, McMahon DB, Miller ZA, Kim T, Rajasekaran K, Gopallawa I, Newman JG, Basu D, Nead KT, White EA, Lee RJ.
DOI: 10.1002/1878-0261.13131
Article
April 15, 2022
Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1
Gosis BS, Wada S, Thorsheim C, Li K, Jung S, Rhoades JH, Yang Y, Brandimarto J, Li L, Uehara K, Jang C, Lanza M, Sanford NB, Bornstein MR, Jeong S, Titchenell PM, Biddinger SB, Arany Z
DOI: 10.1126/science.abf8271
Article
April 8, 2022
α-Synuclein arginylation in the human brain
Zhao J, Pan B, Fina M, Huang Y, Shimogawa M, Luk KC, Rhoades E, Petersson EJ, Dong DW, Kashina A.
DOI: 10.1186/s40035-022-00295-0
Article
April 6, 2022
Cilia Stimulatory and Antibacterial Activities of T2R Bitter Taste Receptor Agonist Diphenhydramine: Insights into Repurposing Bitter Drugs for Nasal Infections
Kuek LE, McMahon DB, Ma RZ, Miller ZA, Jolivert JF, Adappa ND, Palmer JN, Lee RJ.
DOI: 10.3390/ph15040452
Article
April 5, 2022
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function
Desiree M Baron, Adam R Fenton, Sara Saez-Atienzar, Anthony Giampetruzzi, Aparna Sreeram, Shankaracharya, Pamela J Keagle, Victoria R Doocy, Nathan J Smith, Eric W Danielson, Megan Andresano, Mary C McCormack, Jaqueline Garcia, Valérie Bercier, Ludo Van Den Bosch, Jonathan R Brent, Claudia Fallini, Bryan J Traynor, Erika L F Holzbaur, John E Landers
DOI: 10.1016/j.celrep.2022.110598
Article
