October 1, 2025
Acidic Nanoparticles Prevent HIV Pre-Exposure Prophylaxis (PrEP)-Induced Oligodendrocyte Impairments by Restoring Lysosomal pH in Adolescent Models
Claire Mitchell, Ph.D.
Caela C Long, Lindsay K Festa, Melanie Cruz-Berrios, Teshawn D Johnson, Claire H Mitchell, Kelly L Jordan-Sciutto, Judith B Grinspan - PMID: 40676765 PMCID: PMC12334864 DOI: 10.1002/glia.70050
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September 1, 2025
Disease-associated Kv1.3 Variants are Energy Compromised with Impaired Nascent Chain Folding
Carol Deutsch, Ph.D.
Aaron Sykes, Lannawill Caruth, Sophia Gross, Shefali Setia Verma, Toshinori Hoshi, Carol Deutsch - PMID: 40409708 DOI: 10.1016/j.jmb.2025.169226
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August 11, 2025
Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape. Nat Nanotechnol.
Dirk Trauner, PhD
Omo-Lamai S, Wang Y, Patel MN, Milosavljevic A, Zuschlag D, Poddar S, Wu J, Wang L, Dong F, Espy C, Majumder A, Essien EO, Shen M, Channer B, Papp TE, Tobin M, Maheshwari R, Jeong S, Patel S, Shah A, Murali S, Chase LS, Zamora ME, Arral ML, Marcos-Contreras OA, Myerson JW, Hunter CA, Discher D, Gaskill PJ, Tsourkas A, Muzykantov VR, Brodsky I, Shin S, Whitehead KA, Parhiz H, Katzen J, Miner JJ, Trauner D, Brenner JS. - Nat Nanotechnol. 2025 Aug 11. doi: 10.1038/s41565-025-01974-5. Epub ahead of print. PMID: 40789922.
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August 9, 2025
Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy
Erika Holzbaur, Ph.D.
Bishal Basak, Erika L F Holzbaur PMID: 40783388 PMCID: PMC12335601 DOI: 10.1038/s41467-025-62379-5
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August 6, 2025
Mechanical regulation of extracellular vesicle activity during tumour progression
Paul Janmey, Ph.D.
Kshitiz Parihar, Di-Ao Liu, Ghmkin Hassan, David A Issadore, Paul A Janmey, Valerie M Weaver, Wei Guo, Ravi Radhakrishnan - PMID: 40770502 PMCID: PMC12337232 (available on 2026-08-06) DOI: 10.1038/s41551-025-01446-0
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August 6, 2025
Breaking a Lewis Acidity Trend for Rare Earths by Excited State Quenching
Dirk Trauner, PhD
Wilharm RK, Gau MR, Trauner D, Schelter EJ J Am Chem Soc. 2025 Aug 6;147(31):27143-27147. doi: 10.1021/jacs.5c05257. Epub 2025 Jul 24. PMID: 40705825.
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August 5, 2025
What do we know of human fuel use during aerobic exercise and how do we know it?
Zoltan Pierre Arany, MD, PhD
Jessie Axsom, Zolt Arany - PMID: 40763088 DOI:10.1152/physiol.00002.2025
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August 5, 2025
Right Ventricular Dysfunction and Adverse Clinical Outcomes in Peripartum Cardiomyopathy: A Meta-Analysis
Zoltan Pierre Arany, MD, PhD
Ali A Khan, Fayez H Fayad, Chan W Kim, Feven Ataklte, Phinnara Has, Ali Nebipasagil, Zolt Arany, Athena Poppas, Wen-Chih Wu, Gaurav Choudhary, Tasnim F Imran - PMID: 40768944 DOI: 10.1016/j.jacadv.2025.102047
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August 4, 2025
Reprogramming of endolysosomes for melanogenesis in BLOC-1-deficient melanocytes
Michael S. Marks, Ph.D.
Philip S Goff, Shyamal Patel, Dawn C Harper, Tom Carter, Michael S Marks, Elena V Sviderskaya - PMID: 40683250 PMCID: PMC12320751 (available on 2026-07-18) DOI: 10.1016/j.cub.2025.06.031
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July 22, 2025
A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment
Michael Ostap, Ph.D.
Robert C Cail, Bipasha Barua, Faviolla A Báez-Cruz, Donald A Winkelmann, Yale E Goldman, E Michael Ostap - PMID: 40501550 PMCID: PMC12157379 DOI: 10.1101/2025.06.02.657466
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