March 21, 2025
Protocol for live imaging of axonal transport in iPSC-derived iNeurons
Erika Holzbaur, Ph.D.
Dou D, Holzbaur ELF, Boecker CA. STAR Protoc. 2025 Mar 21;6(1):103556. doi: 10.1016/j.xpro.2024.103556. Epub 2025 Jan 12. PMID: 39804773
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March 19, 2025
Dynamics of β-cardiac myosin between the super-relaxed and disordered-relaxed states
Michael Ostap, Ph.D.
Cail RC, Baez-Cruz FA, Winkelmann DA, Goldman YE, Ostap EM. J Biol Chem. 2025 Mar 19:108412. doi: 10.1016/j.jbc.2025.108412. Online ahead of print. PMID: 40118457
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March 11, 2025
Precision Medicine Is in the Eye of the Beholder
Kenneth B. Margulies, M.D.
Circ Heart Fail. 2025 Mar;18(3):e012759. doi: 10.1161/CIRCHEARTFAILURE.125.012759. Epub 2025 Mar 11. PMID: 40066597
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March 10, 2025
TBC1D30 regulates proinsulin and insulin secretion and is the target of a genomic association signal for proinsulin
Damaris Lorenzo
Parsons VA, Vadlamudi S, Voos KM, Rohy AE, Moxley AH, Cannon ME, Rosen JD, Mills CA, Herring LE, Broadaway KA, Lorenzo DN, Mohlke KL. Diabetologia. 2025 Mar 10. doi: 10.1007/s00125-025-06391-w. Online ahead of print. PMID: 40064677
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March 8, 2025
Epigenome-wide association study for dilated cardiomyopathy in left ventricular heart tissue identifies putative gene sets associated with cardiac pathology and early indicators of cardiac risk
Kenneth B. Margulies, M.D.
Tan K, Tay D, Tan W, Ng HK, Wong E, Morley MP, Singhera GK, Lee CJM, Jain PR, Tai FL, Hanson PJ, Cappola TP, Margulies KB, Foo R, Loh M. Clin Epigenetics. 2025 Mar 8;17(1):45. doi: 10.1186/s13148-025-01854-8. PMID: 40057770
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March 5, 2025
Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer
Robert J. Lee, Ph.D
Wei K, Hill BL, Thompson JC, Miller ZA, Mueller A, Lee RJ, Carey RM. Head Neck. 2025 Mar 5;. doi: 10.1002/hed.28120. [Epub ahead of print] PubMed PMID: 40040415; NIHMSID:NIHMS2059808.
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March 4, 2025
Lactate homeostasis is maintained through regulation of glycolysis and lipolysis
Joseph A. Baur, Ph.D.
Lee WD, Weilandt DR, Liang L, MacArthur MR, Jaiswal N, Ong O, Mann CG, Chu Q, Hunter CJ, Ryseck RP, Lu W, Oschmann AM, Cowan AJ, TeSlaa TA, Bartman CR, Jang C, Baur JA, Titchenell PM, Rabinowitz JD. Cell Metab. 2025 Mar 4;37(3):758-771.e8. doi: 10.1016/j.cmet.2024.12.009. Epub 2025 Jan 30. PubMed PMID: 39889702; PubMed Central PMCID: PMC11926601.
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March 4, 2025
High-resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory
Michael Ostap, Ph.D.
Chavali SS, Carman PJ, Shuman H, Ostap EM, Sindelar CV. Proc Natl Acad Sci U S A. 2025 Mar 4;122(9):e2415457122. doi: 10.1073/pnas.2415457122. Epub 2025 Feb 27. PMID: 40014570
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March 1, 2025
Priming and release of cytokine IL-1β in microglial cells from the retina
Claire Mitchell, Ph.D.
Campagno KE, Lu W, Sripinun P, Albalawi F, Cenaj A, Mitchell CH. Exp Eye Res. 2025 Mar;252:110246. doi: 10.1016/j.exer.2025.110246. Epub 2025 Jan 21. PMID: 39848558
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February 28, 2025
Mechanism of actin filament severing and capping by gelsolin.
Roberto Dominguez, Ph.D.
Barrie KR, Rebowski G, Dominguez R. Nat Struct Mol Biol. 2025 Feb;32(2):237-242. doi: 10.1038/s41594-024-01412-5. Epub 2024 Oct 24. PubMed PMID: 39448849; PubMed Central PMCID: PMC11832341.
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