May 4, 2022
Cysteine-Based Mimic of Arginylation Reproduces Neuroprotective Effects of the Authentic Post-Translational Modification on α-Synuclein
Anna Kashina, Ph.D.
Pan B, Shimogawa M, Zhao J, Rhoades E, Kashina A, Petersson EJ. DOI: 10.1021/jacs.2c02499
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May 2, 2022
Acute Deletion of the FOXO1-dependent Hepatokine FGF21 Does not Alter Basal Glucose Homeostasis or Lipolysis in Mice
Paul Titchenell, Ph.D.
Sostre-Colón J, Gavin MJ, Santoleri D, Titchenell PM. DOI: 10.1210/endocr/bqac035
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April 28, 2022
Structural insights into TRPV2 activation by small molecules
Vera Moiseenkova-Bell, Ph.D.
Pumroy RA, Protopopova AD, Fricke TC, Lange IU, Haug FM, Nguyen PT, Gallo PN, Sousa BB, Bernardes GJL, Yarov-Yarovoy V, Leffler A, Moiseenkova-Bell VY. DOI: 10.1038/s41467-022-30083-3
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April 26, 2022
Structural basis of TRPV5 regulation by physiological and pathophysiological modulators
Vera Moiseenkova-Bell, Ph.D.
Fluck EC, Yazici AT, Rohacs T, Moiseenkova-Bell VY. DOI: 10.1016/j.celrep.2022.110737
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April 19, 2022
The microtubule cytoskeleton in cardiac mechanics and heart failure
Benjamin Prosser, Ph.D.
Caporizzo MA, Prosser BL. DOI: 10.1038/s41569-022-00692-y
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April 16, 2022
T2R bitter taste receptors regulate apoptosis and may be associated with survival in head and neck squamous cell carcinoma
Robert J. Lee, Ph.D
Carey RM, McMahon DB, Miller ZA, Kim T, Rajasekaran K, Gopallawa I, Newman JG, Basu D, Nead KT, White EA, Lee RJ. DOI: 10.1002/1878-0261.13131
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April 15, 2022
Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1
Paul Titchenell, Ph.D.
Gosis BS, Wada S, Thorsheim C, Li K, Jung S, Rhoades JH, Yang Y, Brandimarto J, Li L, Uehara K, Jang C, Lanza M, Sanford NB, Bornstein MR, Jeong S, Titchenell PM, Biddinger SB, Arany Z DOI: 10.1126/science.abf8271
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April 8, 2022
α-Synuclein arginylation in the human brain
Anna Kashina, Ph.D.
Zhao J, Pan B, Fina M, Huang Y, Shimogawa M, Luk KC, Rhoades E, Petersson EJ, Dong DW, Kashina A. DOI: 10.1186/s40035-022-00295-0
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April 6, 2022
Cilia Stimulatory and Antibacterial Activities of T2R Bitter Taste Receptor Agonist Diphenhydramine: Insights into Repurposing Bitter Drugs for Nasal Infections
Robert J. Lee, Ph.D
Kuek LE, McMahon DB, Ma RZ, Miller ZA, Jolivert JF, Adappa ND, Palmer JN, Lee RJ. DOI: 10.3390/ph15040452
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April 5, 2022
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function
Erika Holzbaur, Ph.D.
Desiree M Baron, Adam R Fenton, Sara Saez-Atienzar, Anthony Giampetruzzi, Aparna Sreeram, Shankaracharya, Pamela J Keagle, Victoria R Doocy, Nathan J Smith, Eric W Danielson, Megan Andresano, Mary C McCormack, Jaqueline Garcia, Valérie Bercier, Ludo Van Den Bosch, Jonathan R Brent, Claudia Fallini, Bryan J Traynor, Erika L F Holzbaur, John E Landers DOI: 10.1016/j.celrep.2022.110598
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