Adam Fenton (Holzbaur Lab)
Organizing organelles in a neuron: The image highlights the elaborate architecture of a dendritic arbor of a rat hippocampal neuron and depicts contacts between mitochondria (magenta), Rab7-positive late endosomes/lysosomes (cyan), and FMRP-positive RNA granules (yellow) that help determine the organization of this neuron. (Co-authors: Erika Holzbaur, Tom Jongens)
Jennifer Petrosino, PhD (Prosser Lab)
tRNA localization in an adult rat cardiomyocyte. orange stains the microtubules, blue stains tRNA-GlyGCC, and purple stains the nucleus.
Natasha Jaiswal, PhD (Titchenell Lab)
Neuromuscular Junction in Whole Skeletal Muscles: The neuromuscular junction (NMJ) is a complex structure that mediates the cross-talk between motor neurons and muscle fibers, serving as the master controller of many facets of skeletal muscle contractile function. The confocal image of the mature NMJs in EDL muscles shows the postsynaptic apparatus (red pretzel-like nicotinic acetylcholine receptor) and motor neuron (green).
Jose Angel Martinez Sarmiento (Lakadamyali Lab)
Kissing Nuclei: Two human fibroblast cells were experimentally fused into a binucleated cell and their nuclei were imaged using the super-resolution microscopy technique STORM. The picture here is a color-coded rendering of Voronoi density for Histone 2B
Emily Scarborough, PhD (Prosser Lab)
Isolated adult rat cardiomyocyte illustrating the stochasticity of transcriptional activation both among nuclei and among transcripts within the same cell. Hoechst is shown in gray, alpha-actinin protein immunofluorescence is shown in blue, and Actc1 and Actn2 mRNA transcripts are shown in yellow and magenta, respectively.
Charlie Bond (Lakadamyali Lab)
This is a 3D super-resolution image of mitochondria in a cos7 cell. The color bar corresponds to z-position within the cell, with blue corresponding to the lowest point in the cell and red the highest.
Hannah Kim (Lakadamyali Lab)
Super Resolution Image
Kyle Barrie (Dominguez Lab)
This image depicts 4 cryo-EM 2D class averages for the cytoskeletal protein CARMIL. 2D class averages are used in cryo-EM to ensure that the target particle is homogenous and contains well-defined features necessary to determine the structure. These class averages of CARMIL not only depict the well-defined features of the molecule, but also show the unique figure-8 shape formed from antiparallel leucine-rich repeat folds.
Qing Tang, PhD (Lakadamyali Lab)
Super Resolution Image
The Lakadamyali Lab
Super-resolution image of microtubules and tau aggregates (α-tubulin in magenta P301L tau in cyan) (in cells that express GFP-P301L tau and contain tau aggregates) Credit: Melina Gyparaki
Carol Deutsch, PhD
The Deutsch laboratory is the only one studying the early stages of folding of Kv proteins and one of a few laboratories studying the functional biophysical properties of the exit tunnel.
Benjamin Prosser, PhD
Ben is an emerging leader in new, exciting aspects of the molecular physiology of cardiomyocyte function and signaling. The photo featured here is credited to his lab.
Zhe Lu, MD, PhD
Zhe Lu, MD, PhD is an internationally recognized leader in studies of potassium channel ion permeation.
