Ongoing Efforts in Cardiac Arrest Research
The study of cardiac arrest mechanisms, pathobiology, and management are central to the mission of the Center for Resuscitation Science and have formed the backbone of our research since our founding in 2006. We currently have active studies that span the range of research, from studies of biomarkers to clinical trials in post-cardiac arrest care.
Principal Investigator: Benjamin Abella, MD MPhil
Contact: benjamin.abella@pennmedicine.upenn.edu
Dr. Abella studies sudden cardiac arrest, a leading cause of death that claims over 350,000 lives each year in the United States. Specifically, projects within his clinical research team include: (1) evaluation of CPR and resuscitation performance, (2) testing new methods to teach CPR in the community, (3) prognostication of neurologic outcomes after cardiac arrest, and (4) methods to improve post-arrest care and outcomes. Dr. Abella is also the developer and Medical Director of a novel training course for post-arrest care and targeted temperature management (TTM), the Penn TTM Academy.
Dr. Abella has published over 250 scholarly works, reviews and monographs in numerous professional journals including NEJM, JAMA and Circulation, as well as textbook chapters on cardiac arrest and resuscitation. He is Co-Chair of the global Resuscitation Science Symposium and has participated in developing international CPR guidelines. He has won a number of honors for his research, clinical care in the Emergency Department and his teaching of residents and medical students and has lectured widely on the topics of cardiac arrest and post-arrest treatment. The investigative work of Dr. Abella’s team is supported by funding from the NIH and PCORI, as well as industry sources.
Dr. Abella can be found on Twitter @benjaminabella
Benjamin Abella's Recent Publications
-
The Recovery of Consciousness via Evidence-Based Medicine and Research (RECOVER) Program: A Paradigm for Advancing Neuroprognostication.
Neurology. Clinical practice. 2024 Dec;14(6):e200351 Epub 2024 Aug 16; Authors: Fischer D, Abella BS, Bass GD, Charles J, Hampton S, Kulick-Soper CV, Mendlik MT, Mitchell OJ, Narva AM, Pino W, Sikandar ML, Sinha SR, Waldman GJ, Ware JB, Levine JM -
Does targeted temperature management at 33 °C improve outcome after cardiac arrest?
Current opinion in critical care. 2024 Dec 1;30(6):618-623 Epub 2024 Oct 21; Authors: Skrifvars MB, Abella BS -
Development and Implementation of a Multicenter Registry for Resuscitation-Focused Transesophageal Echocardiography.
Annals of emergency medicine. 2024 Oct 15; Authors: Teran F, Owyang CG, Wray TC, Hipskind JE, Lessard J, Bédard Michel W, Lanthier C, Nazerian P, de Villa E, Nogueira J, Doynow D, Clinton M, Myslik F, Prager R, Arntfield R, Salinas PD, Dieiev V, Woo MY, Thavanathan R, Puskas G, Singh K, Bhat P, Horn J, Buchanan BM, Baig N, Burns KM, Kennedy K, Haines L, Naraghi L, Singh H, Secko M, Singer D, Taylor M, Joyce JM, DeMasi S, Jafry ZM, Phan T, Truong N, Robinson E, Haycock KH, Hansen A, Derr C, West FM, Narasimhan M, Horowitz J, Usman A, Anderson KL, Peng Y, Rola P, Andrus P, Razzak J, Hemmings HC, Panchamia R, Palasz J, Kaviyarasu A, Sands NA, Sutton RM, Abella BS, Resuscitative TEE Collaborative Registry (rTEECoRe) Investigators -
Seeking a Treatable Cause of Out-of-Hospital Cardiac Arrest during and after Resuscitation.
Journal of clinical medicine. 2024 Sep 28;13(19); Authors: Halablab SM, Reis W, Abella BS -
Real-time performance improvement optimizes damage control resuscitation best practice adherence: Results of a pilot prospective observational study.
Transfusion. 2024 Sep;64(9):1692-1702 Epub 2024 Jul 27; Authors: Schmulevich D, Geng Z, Joergensen SM, McLauchlan NR, Winter E, Zone A, Bishop KE, Hinkle A, Holland S, Cacchione PZ, Fox EE, Abella BS, Meador CL, Wade CE, Hynes AM, Cannon JW -
Anaerobic Lactate Production Is Associated With Decreased Microcirculatory Blood Flow and Decreased Mitochondrial Respiration Following Cardiovascular Surgery With Cardiopulmonary Bypass.
Critical care medicine. 2024 Aug 1;52(8):1239-1250 Epub 2024 Apr 5; Authors: Greenwood JC, Talebi FM, Jang DH, Spelde AE, Gordon EK, Horak J, Acker MA, Kilbaugh TJ, Shofer FS, Augoustides JGT, Brenner JS, Muzykantov VR, Bakker J, Abella BS -
A Systematic Literature Review to Assess Fever Management and the Quality of Targeted Temperature Management in Critically Ill Patients.
Therapeutic hypothermia and temperature management. 2024 Jun;14(2):68-79 Epub 2023 May 22; Authors: Miao B, Skaar JR, O'Hara M, Post A, Kelly T, Abella BS -
Carbon monoxide as a cellular protective agent in a swine model of cardiac arrest protocol.
PloS one. 2024;19(5):e0302653 Epub 2024 May 15; Authors: Greenwood JC, Morgan RW, Abella BS, Shofer FS, Baker WB, Lewis A, Ko TS, Forti RM, Yodh AG, Kao SH, Shin SS, Kilbaugh TJ, Jang DH -
The Association of Racial Residential Segregation and Survival After Out-of-Hospital Cardiac Arrest in the United States.
medRxiv : the preprint server for health sciences. 2024 Apr 22; Authors: Abbott EE, Buckler DG, Shekhar AC, Landry E, Abella BS, Richardson LD, Zebrowski AM, CARES Surveillance Group -
Using generative artificial intelligence in bibliometric analysis: 10 years of research trends from the European Resuscitation Congresses.
Resuscitation plus. 2024 Jun;18:100584 Epub 2024 Feb 22; Authors: Fijačko N, Creber RM, Abella BS, Kocbek P, Metličar Š, Greif R, Štiglic G