David Snead



David is from Baltimore, Maryland. He graduated from Haverford College as a Chemistry major with a concentration in Biochemistry. He likes playing guitar and juggling. David was a research specialist in the lab from May 2008-June 2009. He went on to join the Tri-institutional MD-PhD Program of Weill Cornell Medical College, The Rockefeller University, and the Sloan-Kettering Institute.


DeSantis, M.E., E.A. Sweeny, D. Snead, E.H. Leung, M.S. Go, K. Gupta, P. Wendler, and J. Shorter. (2014). Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation. J. Biol. Chem. 289(2):848-867. pdf file link

Johnson, B.S., D. Snead, J.J. Lee, J. M. McCaffery, J. Shorter, A.D. Gitler. (2009). TDP-43 is intrinsically aggregation-prone and Amyotrophic Lateral Sclerosis-linked mutations accelerate aggregation and increase toxicity. J. Biol. Chem. 284(30):20329-39 pdf file link

Wendler, P., J. Shorter, D. Snead, C. Plisson, D.K. Clare, S. Lindquist and H.R. Saibil. (2009). Motor mechanism for protein threading through Hsp104. Mol Cell. 34:81-92. pdf file link




Department of Biochemistry & Biophysics
University of Pennsylvania