University of Pennsylvania

The Smell and Taste Center

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Minghong Ma, Ph.D

Minghong MaDepartment of Neuroscience

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Phone: (215)746-2790
110 Johnson Pavilion
Department of Neuroscience
University of Pennsylvania, School of Medicine
Philadelphia, PA 19104


Research Interests

The mammalian olfactory system has the remarkable ability to discriminate thousands of odorants. As the primary neuronal elements in the olfactory system, olfactory sensory neurons are responsible for detecting odor molecules and subsequently sending signals to the brain. These neurons selectively express one or a few olfactory receptor genes from a repertoire of ~1000, the largest gene family in the mammalian genome. We are interested in the functional and molecular organization of the olfactory system and the mechanisms underlying olfactory coding and processing. Our approach combines techniques from different disciplines including optical imaging, patch clamp recording, immunohistochemistry, molecular cloning, in situ hybridization, Affymetrix genechip and gene-targeting.


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