Department of Psychiatry
Penn Behavioral Health

Charles O'Brien Center for Addiction Treatment

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Our Treatment Team

Charles O'Brien, MD, PhD

Charles P. O'Brien, MD, PhD Dr. O'Brien received his MD and PhD degrees from Tulane University, and received residency training in psychiatry, neurology, and medicine at Harvard, the University of London, Tulane and the University of Pennsylvania (Penn). He is board-certified in psychiatry, neurology and addiction psychiatry.

One of the most prominent addiction researchers in the world, Dr. O'Brien has made many important discoveries and contributions over the past 30 years that have become the standard of care in addiction treatment throughout the world. Aside from developing medications to treat alcohol, opioid, and cocaine dependence, his work has also increased the understanding of the clinical aspects of addiction and the neurobiology of relapse.

Among his numerous honors, Dr. O'Brien was elected to the Institute of Medicine of the National Academy of Sciences in 1991, and received the Nathan B. Eddy award for research from the College on Problems of Drug Dependence in 2003. He has advised our national government on drug policy for decades, and was the President of the American College of Neuropsychopharmacology, and the Association for Research in Nervous and Mental Disease.

Dr. O'Brien is the Vice-Chair of Psychiatry at Penn, and the Director of the prestigious Center for Studies in Addiction.


Charles O’Brien Center for Addiction Treatment - Core Staff


Marja Mattila-Evenden, MD

Medical Director

Marja Mattilla-Evenden, MDDr. Marja Mattila-Evenden is a board-certified psychiatrist in General Psychiatry and Addiction Psychiatry.  She received her basic medical training at the University of Helsinki, Finland, where she also was active in clinical research on the psychomotor side-effects and traffic safety of psychotropic medications alone and in combinations in healthy volunteers.  She continued her career with post-doctoral studies and further clinical training at the Karolinska Institute of Clinical Neuroscience, Stockholm, Sweden.  Her research work there was in the areas of suicidology, use of psychiatric rating scale techniques in affective disorders, and psychiatric genetics.  She was employed as an Attending Psychiatrist at the Magnus Huss Clinic, a WHO center of excellence for Addiction Research and Training at the Karolinska Institute.  Dr. Mattila-Evenden completed her US residency in the Dept of Psychiatry and Behavioral Science at Temple University with a fellowship in Addiction Psychiatry at the University of Pennsylvania.

Dr. Mattila-Evenden is specially trained for medication assisted treatments for opioid dependence, and has published scientific and educational articles on benzodiazepine anxiolytics and their interactions with other psychotropic medications.

Andreea Crauciuc, LCSW
Licensed psychotherapist

Andreea Crauciuc, LCSW Ms. Crauciuc received her Master of Social Work degree from the University of Pennsylvania. She is certified as a Licensed Clinical Social Worker by the State Board of Social Workers, Marriage and Family Therapists and Professional Counselors. Before joining our treatment team, she worked at the Hospital of the University of Pennsylvania as a kidney transplant social worker intern, and attended case conferences with the liver transplant team. She then joined the Outpatient Psychiatry Center at the University of Pennsylvania, where she provided psychotherapy services to individuals and couples, many with co-occuring mental health and substance abuse issues. Since joining the Charles O'Brien Center for Addiction Treatment she has specialized in assessing and treating individuals with addictive illnesses, with a special emphasis on working with young adults and their families.



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To learn more about our services or to schedule an appointment, please call (215) 746-5900.