Susan J. Mandel, M.D., M.P.H.

faculty photo
Sylvan H. Eisman Professor of Medicine II
Director, Thyroid Nodule Clinic, Hospital of the University of Pennsylvania
Director, Endocrinology elective for Primary Care Medical Residents
Member, Abramson Cancer Center
Chief, Division of Endocrinology, Diabetes, and Metabolism
Department: Medicine

Contact information
Division of Endocrinology, Diabetes and Metabolism
Perelman School of Medicine, University of Pennsylvania
4th floor West, Perelman Center for Advanced Medicine
3400 Civic Center Blvd
Philadelphia, PA 19104
Education:
A.B. (History of Science)
Harvard University, Cambridge, MA, 1982.
M.D.
Columbia University, College of Physicians and Surgeons, New York, NY, 1986.
M.P.H. (Quantitative methods, decision analysis)
Harvard School of Public Health, Boston, MA, 1997.
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Description of Research Expertise

Thyroid nodules, Thyroid cancer, Thyroid disease and pregnancy, Ultrasound

Description of Clinical Expertise

Thyroid nodules, Thyroid cancer, Thyroid disease and pregnancy, Ultrasound

Dr. Susan J. Mandel, MD, MPH is a Professor of Medicine and Radiology and Chief of the Division of Endocrinology, Diabetes and Metabolism at the Perelman School of Medicine, University of Pennsylvania where she directed the Endocrine fellowship for 22 years. After medical school at the College of Physicians and Surgeons, she completed a medical residency at Columbia Presbyterian Medical Center and a fellowship in endocrinology at the Brigham and Women's. Her clinical practice focuses on patients with thyroid neoplasia and she has been recognized for clinical excellence with the Penn Duhring Clinical Specialist award. Her research interests include the use of sonography in the evaluation of patients with thyroid nodules and cancer, and thyroid disease during pregnancy. Dr. Mandel has over 80 peer reviewed publications in journals including the New England Journal of Medicine, JAMA and the Annals of Internal Medicine. She has also authored chapters on thyroid disorders in Harrison’s Textbook of Medicine and thyroid nodules in Werner and Ingbar’s The Thyroid.

Dr. Mandel has served on the writing groups for the American Thyroid Association (ATA) Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer and the Management of Thyroid Disease during Pregnancy. She is currently co-chairing the 2022 ATA Management Guidelines for Patients with Thyroid nodules. Dr. Mandel also initiated and directed the Ultrasound workshops for the ATA and Endocrine Society. Dr. Mandel has received the Endocrine Society's Distinguished Educator Award, the 2019 WIT Woman of the Year award from the ATA and the H. Jack Baskin Educator Award of the American Association of Clinical Endocrinologists. She is past President of the Endocrine Society, as well as past President of the Association of Program Directors in Endocrinology, Diabetes, and Metabolism.

Selected Publications

Grani G, Del Gatto V, Cantisani V, Mandel SJ, Durante C.: A Reappraisal of Suspicious Sonographic Features of Thyroid Nodules: Shape Is Not an Independent Predictor of Malignancy. J Clin Endocrinol Metab 108: e816-e822, Aug 2023.

Durante C, Hegedüs L, Na DG, Papini E, Sipos JA, Baek JH, Frasoldati A, Grani G, Grant E, Horvath E, Hoang JK, Mandel SJ, Middleton WD, Ngu R, Orloff LA, Shin JH, Trimboli P, Yoon JH, Tessler FN.: International Expert Consensus on US Lexicon for Thyroid Nodules. Radiology 2023.

Ginzberg SP, Soegaard Ballester JM, Wirtalla CJ, Morales KH, Pryma DA, Mandel SJ, Kelz RR, Wachtel H.: Racial and Ethnic Disparities in Appropriate Thyroid Cancer Treatment, Before and After the Release of the 2015 American Thyroid Association Guidelines. Ann Surg Oncol 2023.

Ginzberg SP, Soegaard Ballester JM, Wirtalla CJ, Morales KH, Pryma DA, Mandel SJ, Kelz RR, Wachtel H.: ASO Visual Abstract: Racial and Ethnic Disparities in Appropriate Thyroid Cancer Treatment, Before and After the Release of the 2015 American Thyroid Association Guidelines. Ann Surg Oncol 2023.

Andrianus S, Gubbiotti MA, Mandel SJ, Nikiforov YE, Baloch Z.: Unraveling the significance of TSHR mutations in indeterminate thyroid cytology specimens. Diagn Cytopathol 2023.

Ginzberg SP, Soegaard Ballester JM, Wirtalla CJ, Pryma DA, Mandel SJ, Kelz RR, Wachtel H.: Insurance-Based Disparities in Guideline-Concordant Thyroid Cancer Care in the Era of De-escalation. J Surg Res 2023.

Chou R, Dana T, Mayson SE, Cibas ES, Durante C, Solórzano CC, Mandel SJ, Orloff LA.: Ultrasound Follow-Up of Benign Thyroid Nodules: A Scoping Review. Thyroid 2023.

Mehta V, Naraparaju A, Liao D, Davies L, Haugen BR, Kopp PA, Mandel SJ, Nikiforov YE, Ross DS, Shin JJ, Tuttle RM, Randolph GW.: What's in a Name? A Cost-Effectiveness Analysis of the Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features' Nomenclature Revision. Thyroid Page: 421-428, April 2022.

Kobaly K, Kim CS, Mandel SJ.: Contemporary Management of Thyroid Nodules. Annu Rev Med 73: 517-528, Jan 2022.

Desai D, Lepe M, Baloch ZW, Mandel SJ.: ThyroSeq v3 for Bethesda III and IV: An institutional experience. Cancer Cytopathol 129: 164-170, Feb 2021.

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Last updated: 11/10/2023
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