Susan J. Mandel, M.D., M.P.H.

faculty photo
Sylvan H. Eisman Professor of Medicine II
Director, Thyroid Nodule Clinic, Hospital of the University of Pennsylvania
Director, Endocrinology elective for Primary Care Medical Residents
Member, Abramson Cancer Center
Chief, Division of Endocrinology, Diabetes, and Metabolism
Department: Medicine

Contact information
Division of Endocrinology, Diabetes and Metabolism
Perelman School of Medicine, University of Pennsylvania
4th floor West, Perelman Center for Advanced Medicine
3400 Civic Center Blvd
Philadelphia, PA 19104
A.B. (History of Science)
Harvard University, Cambridge, MA, 1982.
Columbia University, College of Physicians and Surgeons, New York, NY, 1986.
M.P.H. (Quantitative methods, decision analysis)
Harvard School of Public Health, Boston, MA, 1997.
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Description of Research Expertise

Thyroid nodules, Thyroid cancer, Thyroid disease and pregnancy, Ultrasound

Description of Clinical Expertise

Thyroid nodules, Thyroid cancer, Thyroid disease and pregnancy, Ultrasound

Dr. Susan J. Mandel, MD, MPH is a Professor of Medicine and Radiology and Chief of the Division of Endocrinology, Diabetes and Metabolism at the Perelman School of Medicine, University of Pennsylvania where she directed the Endocrine fellowship for 22 years. After medical school at the College of Physicians and Surgeons, she completed a medical residency at Columbia Presbyterian Medical Center and a fellowship in endocrinology at the Brigham and Women's. Her clinical practice focuses on patients with thyroid neoplasia and she has been recognized for clinical excellence with the Penn Duhring Clinical Specialist award. Her research interests include the use of sonography in the evaluation of patients with thyroid nodules and cancer, and thyroid disease during pregnancy. Dr. Mandel has over 80 peer reviewed publications in journals including the New England Journal of Medicine, JAMA and the Annals of Internal Medicine. She has also authored chapters on thyroid disorders in Harrison’s Textbook of Medicine and thyroid nodules in Werner and Ingbar’s The Thyroid.

Dr. Mandel has served on the writing groups for the American Thyroid Association (ATA) Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer and the Management of Thyroid Disease during Pregnancy. She is currently co-chairing the 2022 ATA Management Guidelines for Patients with Thyroid nodules. Dr. Mandel also initiated and directed the Ultrasound workshops for the ATA and Endocrine Society. Dr. Mandel has received the Endocrine Society's Distinguished Educator Award, the 2019 WIT Woman of the Year award from the ATA and the H. Jack Baskin Educator Award of the American Association of Clinical Endocrinologists. She is past President of the Endocrine Society, as well as past President of the Association of Program Directors in Endocrinology, Diabetes, and Metabolism.

Selected Publications

Mehta V, Naraparaju A, Liao D, Davies L, Haugen BR, Kopp PA, Mandel SJ, Nikiforov YE, Ross DS, Shin JJ, Tuttle RM, Randolph GW.: What's in a Name? A Cost-Effectiveness Analysis of the Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features' Nomenclature Revision. Thyroid Page: 421-428, April 2022.

Kobaly K, Kim CS, Mandel SJ.: Contemporary Management of Thyroid Nodules. Annu Rev Med 73: 517-528, Jan 2022.

Desai D, Lepe M, Baloch ZW, Mandel SJ.: ThyroSeq v3 for Bethesda III and IV: An institutional experience. Cancer Cytopathol 129: 164-170, Feb 2021.

Figge JJ, Gooding WE, Steward DL, Yip L, Sippel RS, Yang SP, Scheri RP, Sipos JA, Mandel SJ, Mayson SE, Burman KD, Folek JM, Haugen BR, Sosa JA, Parameswaran R, Tan WB, Nikiforov YE, Carty SE.: Do Ultrasound Patterns and Clinical Parameters Inform the Probability of Thyroid Cancer Predicted by Molecular Testing in Nodules with Indeterminate Cytology? Thyroid Page: 1673-1682, 2021.

Mandel SJ, Langer JE: Clinical Evaluation and Management of Thyroid Nodules. Werner and Ingbar's The Thyroid A Fundamental and Clinical Text, 11th edition. Braverman LE, Cooper DS, Kopp PA (eds.). Wolters Kluwer, 2021.

Desai D, Mandel SJ: A Patient with a Single Thyroid Nodule Suspicious for Follicular Neoplasm According to the Bethesda System for Reporting Thyroid Cytopathology: Molecular Evaluation Thyroid Cancer: A Case-Based Approach, 2nd edition. Grani G, Cooper DS, Durante C (eds.). Springer, 2021.

Brumund KT, Mandel SJ: Ultrasound of the Thyroid and Parathyroid Glands. Surgery of the Thyroid and Parathyroid Glands, 3rd edition. Randolph, GW (eds.). Elsevier, 2021.

Kobaly K, Kim CS, Langer JE, Mandel SJ.: Macrocalcifications Do Not Alter Malignancy Risk Within the American Thyroid Association Sonographic Pattern System When Present in Non-High Suspicion Thyroid Nodules. Thyroid Page: 1542-1548, 2021.

Kobaly K, Mandel SJ, Cappola AR, Kim CS: Letter to the Editor: "Our Response to COVID-19 as Endocrinologists and Diabetologists" Letter to the Editor: "Our Response to COVID-19 as Endocrinologists and Diabetologists". J Clin Endocrinol Metab. 105(7), July 2020.

Sawka AM, Gagliardi AR, Haymart MR, Sturgeon C, Bernet V, Hoff K, Angelos P, Brito JP, Haugen BR, Kim B, Kopp PA, Mandel SJ, Ross DS, Samuels M, Sarne D, Sinclair C, Jonklaas J.: A Survey of American Thyroid Association Members Regarding the 2015 Adult Thyroid Nodule and Differentiated Thyroid Cancer Clinical Practice Guidelines. Thyroid 30(1): 25-33, Jan 2020 Notes:

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Last updated: 08/31/2022
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