Peter C. Adamson, MD

Description of Research Expertise

My primary research focus has been on pediatric cancer drug development, specifically early phase clinical trails and clinical pharmacologic studies. Until 2008 I served as Chair of the Children's Oncology Group (COG) Developmental Therapeutics Programs and Principal Investigator of the COG Phase 1 Consortium, and in 2011 became Chair of the Children's Oncology Group. Prior to becoming the Director of the Office for Clinical and Translational Research at CHOP, I was the Program Director of the General Clinical Research Center (GCRC) and Principal Investigator of its NICHD funded Pediatric Pharmacology Research Unit (PPRU). My laboratory focuses on the clinical pharmacology of new drugs for childhood cancer using an integrated approach that incorporates preclinical studies in both in vitro and animal models, and clinical trials with clinical pharmacokinetic-pharmacodynamic-pharmacogenetic studies in pediatric patients. As Director of the Office for Clinical and Translational Research at CHOP, I work with clinical and translational investigators in identifying scientific opportunities and in forging productive collaborations throughout CHOP and the University of Pennsylvania.

Description of Clinical Expertise

Pediatric oncology
Clinical pharmacology
Relapsed pediatric malignancies