Home | News | Directories | Calendar | Maps | Contact Us | Webmail
Perelman School of Medicine at the University of Pennsylvania Advanced Search

Michael W. Sims, MD, MSCE

Michael W. Sims, MD, MSCE

faculty photo
Assistant Professor of Clinical Medicine
Department: Medicine

Contact information
120 Heart and Vascular Pavillion
Penn Presbyterian Medical Center
51 North 39th Street
Philadelphia, PA 19104
Office: 215-662-8585
Fax: 215-243-4643
Education:
BA (Music; Pre-Medicine)
Franklin and Marshall College, 1993.
MD (Medicine)
University of Pennsylvania School of Medicine, 1998.
MSCE (Master of Science in Clinical Epidemiology)
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 2006.
Permanent link
 
Perelman School of Medicine > Faculty > Search

Description of Research Expertise

Dr. Sims has a strong interest in chronic obstructive pulmonary disease (COPD), with a focus on mechanisms of lung inflammation and disease progression. He is currently the principal investigator of a K23 award from the NIH/NHLBI investigating surfactant protein D as a modulator of lung inflammation and COPD pathogenesis. He has completed a Masters Degree in Clinical Epidemiology at the University of Pennsylvania, and his Master’s Thesis focused on functional consequences of secondary pulmonary hypertension in patients with severe COPD. In addition, as Director of Clinical Research for the Airways Biology Initiative, he is actively involved in ongoing clinical translational research on biomarkers associated with COPD and asthma and bronchoscopic treatments for severe emphysema.

Description of Clinical Expertise

Adult Critical Care
COPD/Emphysema
Lung Volume Reduction Surgery Evaluation
Procedural Treatments for Emphysema

Selected Publications

Sims MW: Acute respiratory failure due to chronic obstructive pulmonary disease. The Intensive Care Unit Manual, 2nd Edition. Lanken PN, Manaker S, Kohl BA, Hanson III CW (eds.). Elsevier, Page: 715-22, 2014.

Lipson DA, Holsclaw D, Imbesi G, Ferrin M, Sims MW, Miller S, Tal-Singer R, Hadjiliadis D: Evidence of Elevated CXCR2 Agonists in Stable Outpatients with Cystic Fibrosis Compared with Healthy Controls. Journal of Pulmonary and Respiratory Medicine 3: 149, 2013.

Sims MW: Bullous lung disease. Clinical Decision Support in Medicine - Epub. Reines L, Grippi M, Kotloff RM (eds.). 2013.

Sims MW, Panettieri RA: Profile of aclidinium bromide in the treatment of chronic obstructive pulmonary disease. International Journal of COPD 6(1): 457-66, September 2011.

Sims MW: Aerosol therapy for obstructive lung diseases: device selection and practice management issues. Chest 140(3): 781–788, September 2011.

Sims MW, Beers MF, Ahya VN, Kawut SM, Sims KD, Lederer DJ, Palmer SM, Wille K, Lama V, Shah PD, Orens JB, Bhorade S, Crespo M, Weinacker A, Demissie E, Bellamy S, Christie JD, and Ware LB for the Lung Transplant Outcomes Group: Effect of Single versus Bilateral Lung Transplantation on Plasma Surfactant Protein D Levels in Idiopathic Pulmonary Fibrosis. Chest 140(2): 489-96, August 2011.

Sims MW, Beers MF, Ahya VN, Kawut SM, Sims KD, Lederer DJ, Palmer SM, Wille K, Lama V, Shah PD, Orens JB Bhorade S, Crespo M, Weinacker A, Demissie E, Bellamy S, Christie JD, and Ware LB for the Lung Transplant Outcomes Group: Effect of Single versus Bilateral Lung Transplantation on Plasma Surfactant Protein D Levels in Idiopathic Pulmonary Fibrosis. Abstract selected for poster discussion at 2010 ATS Conference May 2010.

Sims MW, Musani AI, Sareli C, Russell W, McLaren WJ, Delaney PM, Litzky LA, Panettieri RA: A Pilot Study of the Feasibility of Confocal Endomicroscopy for Examination of the Human Airway. J Bronchol Intervent Pulmonol 17(2): 126-30, April 2010 Notes: Sims & Musani are co-first authors.

Amrani Y, Syed F, Huang C, Li K, Liu V, Jain D, Keslacy S, Sims MW, Baidouri H, Cooper PR, Zhao H, Siddiqui S, Brightling CE, Griswold D, Li L, Panettieri RA: Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13. Respiratory Research 11: 104, 2010.

Sims MW, Margolis D, Localio AR, Panettieri RA, Kawut SM, Christie JD.: Impact of pulmonary artery pressure on exercise function in severe chronic obstructive pulmonary disease. Chest 136: 412-419, August 2009.

back to top
Last updated: 02/05/2014
The Trustees of the University of Pennsylvania