John Plastaras, M.D., Ph.D.
John Plastaras, M.D., Ph.D.
Assistant Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
Department: Radiation Oncology
Contact information
Department of Radiation Oncology
Perelman Center for Advanced Medicine
TRC 4W
3400 Civic Center Blvd.
Philadelphia, PA 19104
Perelman Center for Advanced Medicine
TRC 4W
3400 Civic Center Blvd.
Philadelphia, PA 19104
Office: 215-615-3714
Fax: 215-349-8975
Fax: 215-349-8975
Email:
plastaras@uphs.upenn.edu
plastaras@uphs.upenn.edu
Education:
M.S. (Chemistry)
Emory University, 1994.
B.A. (Biology)
Emory University, 1994.
B.S. (Chemistry)
Emory University, 1994.
Ph.D. (Biochemistry)
Vanderbilt University, 2000.
M.D.
Vanderbilt University, 2002.
Permanent linkM.S. (Chemistry)
Emory University, 1994.
B.A. (Biology)
Emory University, 1994.
B.S. (Chemistry)
Emory University, 1994.
Ph.D. (Biochemistry)
Vanderbilt University, 2000.
M.D.
Vanderbilt University, 2002.
Description of Research Expertise
1. Reirradiation with Proton Therapy: He is the Principal Investigator for the ongoing multicenter clinical study "Proton Radiotherapy for Recurrent Tumors" (ClinicalTrials.gov Identifier: NCT01126476). He is interested in factors that increase the risk of toxicity from reirradiation as well as factors that predict for radioresistance in these recurrent tumors.2. Decreasing Toxicity of Lymphoma Radiotherapy: Interests include developing proton radiotherapy techniques for patients with lymphoma, developing models for predicting radiation-related toxicity, and using highly conformal techniques.
3. Using Moleclar Imaging to Estimate Radiation Dose during Radioimmunotherapy.
4. Proton therapy for gastrointestinal (GI) malignancies: He is the Principal Investigator for the clinical study "Proton therapy for upper GI cancers" (ClinicalTrials.gov Identifier: NCT01449864)
Description of Clinical Expertise
radiation therapy, lymphoma, gastroinstestinal cancer, proton radiotherapy, total body irradiationSelected Publications
Sohal Davendra P S, Metz James M, Sun Weijing, Giantonio Bruce J, Plastaras John P, Ginsberg Gregory, Kochman Michael L, Teitelbaum Ursina R, Harlacker Kathleen, Heitjan Daniel F, Feldman Michael D, Drebin Jeffrey A, O'Dwyer Peter J: Toxicity study of gemcitabine, oxaliplatin, and bevacizumab, followed by 5-fluorouracil, oxaliplatin, bevacizumab, and radiotherapy, in patients with locally advanced pancreatic cancer. Cancer chemotherapy and pharmacology Mar 2013.Wojcieszynski AP, Berman AT, Wan F, Plastaras JP, Metz JM, Mitra N, Apisarnthanarax S: The impact of radiation therapy sequencing on survival and cardiopulmonary mortality in the combined modality treatment of patients with esophageal cancer. Cancer Epub ahead of print, Feb 2013.
Patel V, Buckstein M, Perini R, Hill-Kayser C, Svoboda J, Plastaras JP: CT and PET/CT surveillance after combined modality treatment of supradiaphragmatic Hodgkin Lymphoma: a clinical and economic perspective. Leukemia and Lymphoma Epub ahead of print, Feb 2013.
Joshua A. Jones, MD, Vatsal B. Patel, BA, , Ursina Teitelbaum, MD, John P. Plastaras, MD, PhD: Diffusely metastatic digital papillary adenocarcinoma eleven years after initial presentation treated with palliative chemotherapy and radiotherapy. J Clin Oncol in press, 2013.
Betancourt Ricardo, Zou Wei, Plastaras John P, Metz James M, Teo Boon-Keng, Kassaee Alireza: Abdominal and pancreatic motion correlation using 4D CT, 4D transponders, and a gating belt. Journal of applied clinical medical physics / American College of Medical Physics 14(3): 4060, 2013.
Zou W, Lin H, Plastaras JP, Wang H, Vapiwala N, McDonough J, Tochner Z, Both S: A Clinically Feasible Method for the Detection of Potential Collision in Proton Therapy. Medical Physics 39(11): 7094-101, Nov 2012.
Lukens JN, Nasta SD, Fram B, Glatstein E, Plastaras JP: Outcomes Following Involved Field Radiation Therapy (IFRT) with or without Rituximab in Patients with Early Stage Low-Grade Non-Hodgkin's Lymphoma (NHL) Staged with CT and PETwith CT and PET. American Journal of Clinical Oncology [Epub ahead of print], Sept 2012.
Shen J, Metz JM, Zhu TC, Panetta J, Finlay JC, Xu-Welliver M, Plastaras JP, Bar Ad V, Both S: Dosimetric Consequences of Pancreatic Tumor Motion when Treating with Intensity-Modulated Radiation Therapy (IMRT). Journal of Balkan Union of Oncology 17(3): 526-32, Jul-Sep 2012.
Allen AM, Pawlicki T, Dong L, Fourkal E, Buyyounouski M, Cengel K, Plastaras J, Bucci MK, Yock TI, Bonilla L, Price R, Harris EE, Konski AA: An Evidence Based Review of Proton Beam Therapy: The Report of ASTRO's Emerging Technology Committee. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 103(1): 8-11, Apr 2012.
Kumar AMS, Bui C, Nasta S, Schuster SJ, Plastaras JP: Case Series: Intensity Modulated Radiotherapy to Treat Limited Stage Non-Endemic Nasal Natural Killer/T Cell Lymphoma. Internet Journal of Hematology 8(1): DOI: 10.5580/2c43, 2012.