John Plastaras, M.D., Ph.D.

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Associate Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
Department: Radiation Oncology

Contact information
Department of Radiation Oncology
Perelman Center for Advanced Medicine
TRC 4W
3400 Civic Center Blvd.
Philadelphia, PA 19104
Office: 215-615-3714
Fax: 215-349-8975
Education:
B.S. (Chemistry)
Emory University, 1994.
B.A. (Biology)
Emory University, 1994.
M.S. (Chemistry)
Emory University, 1994.
Ph.D. (Biochemistry)
Vanderbilt University, 2000.
M.D.
Vanderbilt University, 2002.
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Description of Research Expertise

1. Reirradiation with Proton Therapy: He is the Principal Investigator for the ongoing multicenter clinical study "Proton Radiotherapy for Recurrent Tumors" (ClinicalTrials.gov Identifier: NCT01126476). He is interested in factors that increase the risk of toxicity from reirradiation as well as factors that predict for radioresistance in these recurrent tumors.

2. Decreasing Toxicity of Lymphoma Radiotherapy: Interests include developing proton radiotherapy techniques for patients with lymphoma, developing models for predicting radiation-related toxicity, and using highly conformal techniques.

3. Using Molecular Imaging to Estimate Radiation Dose during Radioimmunotherapy.

4. Proton therapy for gastrointestinal (GI) malignancies: He is the Principal Investigator for the clinical study "Proton therapy for upper GI cancers" (ClinicalTrials.gov Identifier: NCT01449864)

Description of Clinical Expertise

radiation therapy, lymphoma, gastroinstestinal cancer, proton radiotherapy, total body irradiation

Selected Publications

Plastaras JP, Chong EA, Schuster SJ: Don't Get Stuck on the Shoulder: Radiation Oncologists Should Get Into the CAR With T-Cell Therapies. International Journal of Radiation Oncology, Biology, Physics December 2019.

Bauman Brittany, Mick Rosemarie, Martinez Eileen, Lawless Theresa M, Zinck Lindsey, Sinclair Paige, Fuhrer Mary, O'Hara Mark, Schneider Charles J, O'Dwyer Peter, Plastaras John, Teitelbaum Ursina, Reiss Kim A: Efficacy of Oral Cryotherapy During Oxaliplatin Infusion in Preventing Oral Thermal Hyperalgesia: A Randomized Trial. Journal of the National Comprehensive Cancer Network : JNCCN 17(4): 358-364, April 2019.

Demissei Biniyam G, Freedman Gary, Feigenberg Steven J, Plastaras John P, Maity Amit, Smith Amanda M, McDonald Caitlin, Sheline Karyn, Simone Charles B, Lin Lilie L, Carver Joseph R, Liu Peter, Zhang Liyong, Bekelman Justin E, Ky Bonnie: Early Changes in Cardiovascular Biomarkers with Contemporary Thoracic Radiation Therapy for Breast Cancer, Lung Cancer, and Lymphoma. International journal of radiation oncology, biology, physics 103(4): 851-860, March 2019.

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Last updated: 09/17/2020
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