Yongping Wang, MD, PhD
Associate Professor of Clinical Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine
Contact information
Cell and Gene Therapy Lab
Department of Pathology and Laboratory Medicine
5NW60 Main Building
Children's Hospital of Philadelphia
3401 Civic Center Blvd
Philadelphia, PA 19104
Department of Pathology and Laboratory Medicine
5NW60 Main Building
Children's Hospital of Philadelphia
3401 Civic Center Blvd
Philadelphia, PA 19104
Office: 215-590-4759
Lab: 215-590-2807
Lab: 215-590-2807
Email:
wangy2@chop.edu
wangy2@chop.edu
Education:
B.S. (Molecular Biophysics and Biochemistry; Economics)
Yale, 1995.
M.D, Ph.D. (Medicine; Pharmacology)
Dartmouth Medical School, 2003.
Permanent linkB.S. (Molecular Biophysics and Biochemistry; Economics)
Yale, 1995.
M.D, Ph.D. (Medicine; Pharmacology)
Dartmouth Medical School, 2003.
Description of Clinical Expertise
cGMP cellular therapy, stem cell, bone marrow transplant, mesenchymal stromal cell (MSC), chimeric antigen receptor T cells (CARTs)Description of Research Expertise
RNAi, library screening, stem cell, erythropoiesisSelected Publications
Edo Schaefer, MD, Allyson Flower, MD, Janet Ayello, MS, MT, Yaya Chu, PhD, Carmella van De Ven, MS, Elizabeth Mintzer, Lauren Harrison, RN, MSN, Erin Morris, RN, Yongping Wang, MD, PhD, Shalini Shenoy, MD, MBBS, Dean Lee, MD, PHD, Rolla Abu-Arja, MD, Bryon D. Johnson, PhD, Michael R. Verneris, MD, Christopher C. Dvorak, MD, Julia Chu, MD, MPH, Kenneth R. Cooke, MD, Julie Talano, MD, Nancy Bunin, MD, Mitchell S. Cairo, MD: Treatment of Refractory Cytomegalovirus (CMV) Infections using CMV-specific Cytotoxic T-lymphocytes (CTLs) in Children, Adolescents and Young Adults (CAYA) Post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or Solid Organ Transplant (SOT). Pediatric Transplantation and Cellular Therapy Consortium Annual meeting, Seattle, WA Apr 2024.Edo Schaefer, MD Christine Vu, DO Allyson Flower, MD Janet Ayello, MS, MT(ASCP) Yaya Chu, PhD Carmella van de Ven, MA Elizabeth Mintzer Lauren Harrison, RN, MSN Erin Morris, RN, BSN Yongping Wang, MD, PhD Shalini Shenoy, MD Dean Anthony Lee, MD, PhD Rolla Abu-Arja, MD Bryon D Johnson, PhD Michael R. Verneris, MD Christopher C. Dvorak, MD Julia Chu, MD Kenneth R. Cooke, MD Julie A Talano, MD Nancy J. Bunin, MD Mitchell S. Cairo, MD: Adenoviral Cellular Therapy with Adenovirus (ADV)-specific Cytotoxic T-lymphocytes (CTLs) for Resistant Infections in Children, Adolescent, and Young Adult (CAYA) Patients Following Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT): A Promising Approach. Transplantation and Cellular Therapy 30(2): S432, Feb 2024.
Susan E. McClory, MD, PhD Caitlin W. Elgarten, MD, MSCE Kaitlyn N Quijano Anne Wohlschlaeger, MSN, CRNP Mrs. Patricia Hankins, BSN, RN Lei Wang, PhD Yongping Wang, MD, PhD Stephan Kadauke, MD, PhD Dimitri Monos, PhD Timothy S. Olson, MD, PhD Stephan A. Grupp, MD, PhD Elisa Ochfeld Jennifer R. Heimall, MD Nancy J. Bunin, MD: Unrelated and Haploidentical Peripheral Stem Cell Transplant with TCRαβ/CD19 Depletion for the Treatment of Pediatric Patients with Inborn Errors of Immunity. Transplantation and Cellular Therapy 30(2): S68, Feb 2024.
Nora M. Gibson, MD Caitlin W. Elgarten, MD, MSCE Joseph H. Oved, M.D. M.A. Lisa Wray, MD Jason L. Freedman, MD, MSCE Yongping Wang, MD, PhD Stephan Kadauke, MD, PhD Patricia Hankins, BSN, RN, CCRC Peter Nicholas Elizabeth Worster, CRNP Janet L. Kwiatkowski, MD, MSCE Stephan A. Grupp, MD, PhD Nancy J. Bunin, MD Timothy S. Olson, MD, PhD: Outcomes of Unrelated Partial T Cell Depleted Stem Cell Transplantation for Patients with Hemoglobinopathies. Transplantation and Cellular Therapy 30(2): S301, Feb 2024.
Caitlin W. Elgarten, MD, MSCE Stephanie Heidemann, MD Jason L. Freedman, MD, MSCE Stephan A. Grupp, MD, PhD Patricia Hankins, BSN, RN, CCRC Stephan Kadauke, MD, PhD Yimei Li, PhD Barbara McGlynn, BSN, RN Timothy S. Olson, MD, PhD Yongping Wang, MD, PhD Lisa Wray, MD Lei Wang, PhD Alix E. Seif, MD, MPH Nancy J. Bunin, MD: Pilot study of unrelated donor (URD) peripheral stem cell transplant (PSCT) with CD45RA depleted addback following TCRab/CD19 depletion in pediatric patients with hematologic malignancies. Transplantation and Cellular Therapy 30(2): S9, Feb 2024.
Arwa Z. Al-Riyami, Elena Maryamchik, Richard S. Hanna, Amir Reza Pashmineh Azar, Xingwu Zheng, Shilpa Choudhari, Colleen Finn, Nicholas Giacobbe, Rene Machietto, Robert Rieser, Farzaneh Ghasemi Tahrir, Xiaoyong Zhang, Stephan Kadauke, Yongping Wang: A Machine Learning Model That Incorporates CD45 Surface Expression Predicts Hematopoietic Progenitor Cell Recovery After Freeze-thaw. Cytotherapy 25(10): 1048-1056, Oct 2023.
Rene Machietto, Nicholas Giacobbe, Jessica Perazzelli, Ted J. Hofmann, Allison Barz Leahy, Stephan A. Grupp, Yongping Wang, Stephan Kadauke: Chimeric Antigen Receptor T Cell Manufacturing on an Automated Cell Processor. J Vis Exp 198: doi: 10.3791/65488 online only, Aug 2023.
Laura Breda, Tyler E. Papp, Michael P. Triebwasser, Amir Yadegari, Megan T. Fedorky, Naoto Tanaka, Osheiza Abdulmalik, Giulia Pavani, Yongping Wang, Stephan A. Grupp, Stella Chou, Houping Ni, Barbara L. Mui, Ying K. Tam, Drew Weissman, Stefano Rivella and Hamideh Parhiz: In vivo modification of hematopoietic stem cells by targeted lipid nanoparticles delivering mRNA. Science 381(6656): 436-443, Jul 2023.
Yaya Chu, Jordan Milner, Margaret Lamb, Elena Maryamchik, Olivia Rigot, Janet Ayello, Lauren Harrison, Rosemarie Shaw, Gregory K. Behbehani6, Elaine R. Mardis, Katherine Miller, Lakshmi Prakruthi Rao Venkata, Hsiaochi Chang, Dean Lee, Elana Rosenthal, Stephan Kadauke, Nancy Bunin, Julie-An Talano, Bryon Johnson, Yongping Wang*, and Mitchell S. Cairo* (*co-senior author): Manufacture and Characterization of GMP-Compliant SARS-COV-2 Cytotoxic T Lymphocytes. The Journal of Infectious Diseases 227(6): 788-799, Mar 2023.
Emily Roth, Danielle Reahm, Anna D'Aprile, Jason L Freedman, Stephan A. Grupp, and Yongping Wang: Infusing Collaboration: Stem Cell Infusion Day Procedures. American Society of Transplantation & Cellular Therapy annual meeting. Orlando, FL. Feb 2023.