Yongping Wang, MD, PhD

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Assistant Professor of Clinical Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
Cell and Gene Therapy Lab, 5NW60 Main Building
Children's Hospital of Philadelphia
3401 Civic Center Blvd
Philadelphia, PA 19104
Office: 215-590-4759
Lab: 215-590-2807
Education:
B.S. (Molecular Biophysics and Biochemistry; Economics)
Yale, 1995.
M.D, Ph.D. (Medicine; Pharmacology)
Dartmouth Medical School, 2003.
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Description of Clinical Expertise

cGMP cellular therapy, stem cell, bone marrow transplant, mesenchymal stromal cell (MSC), chimeric antigen receptor T cells (CARTs)

Description of Research Expertise

RNAi, library screening, stem cell, erythropoiesis

Selected Publications

Oved JH, Wang Y, Huang Y, Monos D, Barrett DM, Grupp SA, Bunin NJ, and Olson TS: Two Partial T cell Depletion Strategies for Unrelated Donor Peripheral Stem Cell Trans-plantation are associated with excellent outcomes for pediatric patients with bone mar-row failure ASBMT Tandem Mtg, Salt Lake City, UT Feb 2018.

Benjamin Laskin, Alix Seif, Nancy Bunin, Yongping Wang, Ulf Beier, Michelle Altrich, Sonata Jodele, Stella Davies, and Michelle Denburg: BK viremia in children after allogeneic hematopoietic cell transplant. ASBMT Tandem Mtg, Salt Lake City, UT Feb 2018.

Mala Kiran Talekar, Yongping Wang, Dimitri S. Monos, Stephan A. Grupp, Nancy Bunin and Timothy Olson. : CD3/CD19 Depletion with Targeted T Cell Add-Back Results in Stable Engraftment and Minimal GVHD in Pediatric Patients with Bone Marrow Failure Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplantation. BMT Tandem Meeting, Honolulu, HI Feb 2016.

Jason L. Freedman, Yongping Wang, Yimei Li, Dmitri Monos, David Barrett, Alix Seif, David T. Teachey, Timothy Olson, Stephan Grupp, and Nancy Bunin. : Unrelated and Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) using TCR-αβ+CD3+ Depletion in Pediatric Patients with Hematologic Malignancies. BMT Tandem Meeting, Honolulu, HI Feb 2016.

Alix E. Seif, Yimei Li, Richard Aplenc, David M. Barrett, James T. Casper, Jason L. Freedman, Stephan A. Grupp, David A. Margolis, Timothy S. Olson, David T. Teachey, Yongping Wang, Julie-An M. Talano, and Nancy J. Bunin. : Favorable chronic graft-versus-host-disease (GVHD), event-free (EFS), and overall survival (OS) rates following partially CD3-depleted alternative donor peripheral stem cell transplantation (PSCT) for pediatric hematologic malignancies. BMT Tandem Meeting, Honolulu, HI Feb 2016.

Cotticelli, M.G., Acquaviva, F., Xia S., Kaur, A., Wang, Y., and Wilson, R.B: Phenotypic screening for Friedreich ataxia using random shRNA selection. Journal of Biomolecular Screening 20(9): 1084, Oct 2015.

Yongping Wang and Deborah Sesok-Pizzini: Academia and Industry Collaborate in Cellular Therapy Partnerships. AABB News Page: 8-10, May 2015.

Wang Y, Speier JS, Engram-Pearl J, Wilson RB: Introduction of Mismatches in a Random shRNA-encoding Library Improves Potency for Phenotypic Selection. PLoS One 9(2): e87390, Feb 2014.

Hanley PJ, Mei Z, da Cabreira-Hansen M, Klis M, Li W, Zhao Y, Durett AG, Zheng X, Wang Y, Gee AP, and Horwitz EM: Manufacturing Mesenchymal Stromal Cells for Phase I Clinical Trials. Cytotherapy 15(4): 416-422, Apr 2013.

Wang Y, Wang YE, Cotticelli MG and Wilson RB: A Random shRNA-Encoding Library for Phenotypic Selection and Hit-Optimization Cambridge Healthtech Institute’s 8th International Discovery On Target Meeting, Boston, MA 2010.

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Last updated: 11/07/2017
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