Michele P Lambert, MD, MTR

faculty photo
Associate Professor of Pediatrics (Hematology) at the Children's Hospital of Philadelphia
Attending Physician, Division of Hematology, Children's Hospital of Philadelphia
Consulting Attending Physician, Section of Hematology/Oncology, Pennsylvania Hospital
Consulting Physician, Section of Newborn Pediatrics, Hospital of the University of Pennsylvania
Medical Director, Special Coagulation Laboratory, Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia
Co-Director, Frontier Program in Immune Dysregulation, Children's Hospital of Philadelphia
Director, Pediatric Platelet Disorder Program, Division of Hematology, Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Hematology
3615 Civic Center Blvd
Philadelphia, PA 19083
Office: 215-590-4667
Fax: 267-426-5476
Lab: 215-590-1971
Education:
BS (Biology)
Rensselaer Polytechnic Institute, 1995.
MD
UMDNJ - New Jersey Medical School, 1999.
MTR (Translational Research)
University of Pennsylvania School of Medicine, 2010.
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Selected Publications

Harris EM, Pincez T, Hillier K, Ting Y-L, DiRaimo J, Helber H, o'Farrell C, Lecluze E, Kim T, Grace RF, Scheurer M, Hale R, Shimano K, Nugent D, Neufeld EJ, Platt C, Lambert MP, Grimes A, Kaicker S.: Germline Genetic Testing Uncovers a High Frequency of Inborn Error of Immunity Diagnoses in Children with Single and Multi-Lineage Immune Cytopenias in a Large U.S. Cohort. American Society of Hematology Annual Meeting, Orlando, FL December 2025.

Lambert MP, Cooper N, Izquierdo CP, Lucchini E, Audia S, Wang H, Miyakawa Y, Foster MC, Rodriguez MB, Daak A, Kuter DJ: Reproductive health in patients with primary immune thrombocytopenia (ITP) receiving rilzabrutinib: A subgroup analysis from the Phase 3 LUNA3 multicenter study. American Society of Hematology Annual Meeting, Orlando, FL December 2025.

Ross M, Phillips L, Pierce K, Charland D, El Haouzi N, Konde P, Mueler M, Montcrief C, Ukropina S, Wang K, Grace RF, Klaassen RJ, Lambert MP, Remiker A, Hillier K.: Treatment strategies and outcomes in pediatric patients with immune thrombocytopenia (ITP) undergoing surgical procedures: A multicenter study. American Society of Hematology Annual Meeting, Orlando, FL December 2025.

Shimano KA, Grimes AB, Rose MJ, Kaicker S, Shah SJ, Briones M, Gunne E, Nakano TA, Lebensburger JD, Lambert MP, Fritch-Lilla SA, Jesudas R, Lee-Miller CA, Thompson AT, Kochhar M, Crary SE, Hege K, Rothman JA, Ford JB, Bies JJ, Wynn TT, Hsieh L, Ruiz ME, Dinu B, Wong JMW, Kao P-C, Arnold SD, Bennet CM, Despotovic J, Klaassen RJ, Neufeld EJ, Neuner CE, London WB, Grace RF : End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children. American Society of Hematology Annual Meeting, Orlando, FL December 2025.

Brakhane M, Abbonante V, Laranjieira A, DiBuduo C, Sadler B, Ashworth K, Kong T, Letson C, He F, Fulbright M, Siner J, Chen D, Clemens R, Pegoraro E, Lambert MP, Gollomp K, DiPaola J, Balduini A, Oh S: Activating STIM1 mutations drive the development of myelofibrosis. American Society of Hematology Annual Meeting, Orlando, FL December 2025.

Harris E, Montcrieff C, Farre C, Konde P, Grimes AB, Lambert MP, Grace RF: Real-World Use of Avatrombopag in Children and Adolescents with ITP. Pediatric Blood and Cancer Page: e32143, November 2025.

Shimano KA, Grimes AB, Kaicker S, Shah SJ, Gunn E, Bhat RV, Kochhar M, Rothman JA, Rose MJ, Briones M, Nakano TA, Lebensburger JD, Lambert MP, Fritch Lilla SA, Jesudas R, Lee-Miller CA, Thompson AA, Rifkin-Zenenberg S, Majumdar S, Crary SE, Hege K, Ford JB, Bies JJ, Fort J, Wynn TT, Hsieh L, Ruiz ME, Dinu B, Wong JMW, Kao PC, Kim TO, Arnold SD, Bennett CM, Despotovic JM, Klaassen RJ, Neufeld EJ, Neunert CE, London WB, Grace RF.: Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment: The PINES Randomized Clinical Trial. JAMA Oct 2025.

Coletti K, Hershey JA, Devine M, Taft J, Schinella J, Ajiboye S, Gibbs K, Lambert MP, Friedman D, Thom CS.: An improvement project standardizing low prophylactic platelet transfusion dosing for infants. J Perinatol 9(1): doi: 10.1038, September 2025 Notes: epub ahead of print.

Al-Huniti A, Haley K, Sarode R, Lambert MP, Zia A, Doshi BS: PB0986 - Systematic review on the management of hemostatic defects in children with liver disease. ISTH Meeting 2025, Washington, DC (Poster) June 2025.

Grace RF, Leblesbisatan G, Aydinok Y, Unal S, Grainger J, Grimes A, Lambert MP, Zhang J, Jameson B, Vredenburg M, Kolodny S: PB0348 - Consistent Response to Avatrombopag for Pediatric ITP Across Various Baseline Characteristics. ISTH Meeting 2025, Washington, DC (Poster) June 2025.

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Last updated: 11/11/2025
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