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Michele Puszkarczuk Lambert, MD

Michele Puszkarczuk Lambert, MD

faculty photo
Assistant Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Hematology
3615 Civic Center Blvd
ARC 316G
Philadelphia, PA 19083
Office: 215-590-4667
Fax: 267-426-5476
Lab: 215-590-1971
Education:
BS (Biology)
Rensselaer Polytechnic Institute, 1995.
MD (Medicine)
UMDNJ - New Jersey Medical School, 1999.
MTR
University of Pennsylvania, 2010.
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Selected Publications

Kumar Manjusha, Lambert Michele P, Breakey Vicky, Buchanan George R, Neier Michelle, Neufeld Ellis J, Kempert Pamela, Neunert Cindy E, Nottage Kerri, Klaassen Robert J: Sports Participation in Children and Adolescents with Immune Thrombocytopenia (ITP). Pediatric blood & cancer 62(12): 2223-5, Dec 2015.

Fuentes Rudy E, Zaitsev Sergei, Ahn Hyun Sook, Hayes Vincent, Kowalska M Anna, Lambert Michele P, Wang Yuhuan, Siegel Donald L, Bougie Daniel W, Aster Richard H, Myers Daniel D, Stepanova Victoria, Cines Douglas B, Muzykantov Vladimir R, Poncz Mortimer: A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation. The Journal of clinical investigation Dec 2015.

Lambert M P, Meng R, Xiao L, Harper D C, Marks M S, Kowalska M A, Poncz M: Intramedullary megakaryocytes internalize released platelet factor 4 and store it in alpha granules. Journal of thrombosis and haemostasis : JTH 13(10): 1888-99, Oct 2015.

Bride Karen L, Vincent Tiffaney, Smith-Whitley Kim, Lambert Michele P, Bleesing Jack J, Seif Alix E, Manno Catherine S, Casper James, Grupp Stephan A, Teachey David T: Sirolimus is effective in relapsed/refractory autoimmune cytopenias: results of a prospective multi-institutional trial. Blood 127(1): 17-28, Oct 2015.

Bussel James B, de Miguel Purificación Garcia, Despotovic Jenny M, Grainger John D, Sevilla Julián, Blanchette Victor S, Krishnamurti Lakshmanan, Connor Philip, David Michèle, Boayue Koh B, Matthews Dana C, Lambert Michele P, Marcello Lisa M, Iyengar Malini, Chan Geoffrey W, Chagin Karen D, Theodore Dickens, Bailey Christine K, Bakshi Kalpana K: Eltrombopag for the treatment of children with persistent and chronic immune thrombocytopenia (PETIT): a randomised, multicentre, placebo-controlled study. The Lancet. Haematology 2(8): e315-25, Aug 2015.

Westbury Sarah K, Turro Ernest, Greene Daniel, Lentaigne Claire, Kelly Anne M, Bariana Tadbir K, Simeoni Ilenia, Pillois Xavier, Attwood Antony, Austin Steve, Jansen Sjoert Bg, Bakchoul Tamam, Crisp-Hihn Abi, Erber Wendy N, Favier Rémi, Foad Nicola, Gattens Michael, Jolley Jennifer D, Liesner Ri, Meacham Stuart, Millar Carolyn M, Nurden Alan T, Peerlinck Kathelijne, Perry David J, Poudel Pawan, Schulman Sol, Schulze Harald, Stephens Jonathan C, Furie Bruce, Robinson Peter N, van Geet Chris, Rendon Augusto, Gomez Keith, Laffan Michael A, Lambert Michele P, Nurden Paquita, Ouwehand Willem H, Richardson Sylvia, Mumford Andrew D, Freson Kathleen: Human phenotype ontology annotation and cluster analysis to unravel genetic defects in 707 cases with unexplained bleeding and platelet disorders. Genome medicine 7(1): 36, April 2015.

Spinler Kyle R, Shin Jae-Won, Lambert Michele P, Discher Dennis E: Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia. Blood 125(3): 525-33, Jan 2015.

Bruns Ingmar, Lucas Daniel, Pinho Sandra, Ahmed Jalal, Lambert Michele P, Kunisaki Yuya, Scheiermann Christoph, Schiff Lauren, Poncz Mortimer, Bergman Aviv, Frenette Paul S: Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion. Nature medicine 20(11): 1315-20, Oct 2014.

Greene Teshell K, Lyde Randolph B, Bailey Shahara C, Lambert Michele P, Zhai Li, Sabatino Denise E, Camire Rodney M, Arruda Valder R, Poncz Mortimer: Apoptotic Effects of Platelet Factor VIII on Megakaryopoiesis: Implications for a Modified Human Factor VIII for Platelet-based Gene Therapy. Journal of thrombosis and haemostasis : JTH 12(12): 2102-12, Oct 2014.

Schultz Corinna L, Mitra Nandita, Schapira Marilyn M, Lambert Michele P: Influence of the american society of hematology guidelines on the management of newly diagnosed childhood immune thrombocytopenia. JAMA pediatrics 168(10): e142214, Oct 2014.

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Last updated: 01/13/2016
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