Home | News | Directories | Calendar | Maps | Contact Us | Webmail
Perelman School of Medicine at the University of Pennsylvania Advanced Search

Christopher G. Ward, MD

Christopher G. Ward, MD

faculty photo
Assistant Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care

Contact information
The Children's Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
34th Street & Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-0581
University of Pennsylvania, 2000.
Jefferson Medical College, 2004.
Permanent link
Perelman School of Medicine > Faculty > Search

Description of Clinical Expertise

Dr. Ward's clinical areas of expertise are in pediatric neuroanesthesia and advanced airway modalities for difficult pediatric airways.

Description of Research Expertise

Dr. Ward investigates anesthetic induced neurotoxicity in the developing brain using rodent models. His lab examines both histopathological changes in the brain as well as learning and behavior changes associated with anesthetic drug exposure in neonatal and juvenille rodents.

Selected Publications

Rylon D, Hofacer BS, Meng D, Ward CG, Bernadin J, Hughes EA, Jiang C, Danzer SC, Loepke AW: Cell-age specific vulnerability of neurons to anesthetic toxicity. Annals of Neurology In Press 2013.

Istaphanous GK, Ward CG, Nan X, Hughes EA, McCann JC, McAuliffe JJ, Danzer SC, Loepke AW: Characterization and quantification of isoflurane-induced developmental apoptotic cell death in mouse cerebral cortex. Anesthesia and Analgesia 116(4), 2013.

Ward CG, Hughes E, Joseph B, Hofacer R, Choe YS, Danzer S, Loepke AW: Vulnerability to anesthetic-induced neuroapoptosis is determined by the maturational age of the cell and not the age of the animal. (Oral presentation during awards presentation) SPA/AAP Pediatric Anesthesiology 2012.

Ward CG, Loepke AW: Anesthetics and sedatives: Toxic or protective for the developing brain? Pharmacological Research 2011.

Ward CG, Wei H: Multiples of minimal alveolar concentrations of volatile agents are not necessarily equipotent. [Letter to the Editor] Anesthesiology 114(1): 221-222, 2011.

Liang G, Ward CG, Peng J, Zhao Y, Huang B, Wei H : Isoflurane causes greater neurodegeneration than an equivalent exposure of sevoflurane in the developing brain of neonatal mice. Anesthesiology 112: 1325-1334, 2010.

Istaphanous G, Ward CG, Loepke AW: The impact of the perioperative period on neurocognitive development, with a focus on pharmacological concerns. Best Practice and Research Clinical Anaesthesiology 24(3): 433-449, 2010.

Liang G, Huang B, Peng J, Zhao Y, Fazen Eckenhoff ME, Ward CG, Wei H: Equipotent exposure of sevoflurane causes significantly less neurodengeneraton than isoflurane during brain development in newborn mice. (Presented during the poster discussion for Mechanisms of Neurotoxicity and Neuroprotection.) Neuroscience Annual Meeting 2009.

Ward CG, Cook-Sather S, McCloskey J, Rehman M: Operator dependent data entry in an Anesthesia information system is not a reliable resource for retrospective clinical outcomes research. (Presented during the poster discussion at the Society for Technology in Anesthesia Annual Meeting, 2009.). Society for Technology in Anesthesia Annual Meeting 2009.

Ward CG, Wei H, Liang G, Wang S, Zhao Y: Neonatal exposure to isoflurane does not cause learning deficits in the developing mouse brain. (Presented as a scientific paper oral presentation for “Pediatric Anesthesia: Techniques and the developing Brain”- American Society of Anesthesiologists Annual Meeting, 2008.). Anesthesiology 109: A201, 2008.

back to top
Last updated: 08/28/2013
The Trustees of the University of Pennsylvania