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Christopher G. Ward, MD

Christopher G. Ward, MD

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Assistant Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care

Contact information
The Children's Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
34th Street and Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-0581
BA (Medicine)
University of Pennsylvania, 2000.
MD (Biology)
Jefferson Medical College, 2004.
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Perelman School of Medicine > Faculty > Search

Description of Clinical Expertise

Dr. Ward's clinical areas of expertise are in pediatric neuroanesthesia, advanced airway modalities for difficult pediatric airways, and the anesthesia care of patients with epidermolysis bullosa.

Description of Research Expertise

Dr. Ward investigates anesthetic induced neurotoxicity in the developing brain using rodent models. His lab examines both histopathological changes in the brain as well as learning and behavior outcomes associated with anesthetic drug exposure in neonatal and juvenille rodents. He also is involved in 2 clinical trials examining the effects of anesthesia on NIRS output and the TREX study evaluating dexmedetomidine and remifentanyl combined with caudal analgesia for urologic procedures.

Selected Publications

Ward, CG, Hogan, KJ, Eckenhoff RG: Post-operative cognitive risk exists at all ages. JAMA 2015.

Ward CG, Hines SJ, Maxwell LG, McGowan FX, Sun LS.: Neurotoxicity, general anesthesia in young children, and a survey of current pediatric anesthesia practice at US teaching institutions. Paediatr Anaesth 26(1), 2015.

Ward CG, DeYoung T,Eckenhoff MF, Eckenhoff RG, Barr G: Mortality differences between C57BL/6 mice from Jackson and Charles River Laboratories due to exposure to isoflurane. Society for Neuroscience Conference, Chicago 2015 Notes: Oral presentation for Neurotoxicity and neurodegeneration nano-symposium at the Society for Neuroscience Conference, Chicago.

Ward CG, DeYoung T,Eckenhoff MF, Eckenhoff RG, Barr G: Primarily neocortical but not hippocampal dentate gyrus anesthetic-induced apoptosis in mice leads to a deficit in context pre-exposure facilitation effect. Society of Pediatric Anesthesia/AAP Winter Meeting 2015 Notes: Presented at Moderated Poster Discussion, Neuro Group

Ward CG, Nhundu B, Barr G: Hippocampal dentate gyrus anesthetic-induced apoptosis does not effect context pre-exposure facilitation effect in mice. SPA/AAP Pediatric Anesthesiology Conference 2014 Notes: Presented at Moderated Poster Discussion, Neuro Group

Hofacer RD*, Meng D*, Ward CG*, Bernadin J, Hughes EA, Jiang C, Danzer SC, Loepke AW: Cell-age specific vulnerability of neurons to anesthetic toxicity. Annals of Neurology 73(6): 695-704, 2013 Notes: *co-first authors.

Istaphanous GK, Ward CG, Nan X, Hughes EA, McCann JC, McAuliffe JJ, Danzer SC, Loepke AW: Characterization and quantification of isoflurane-induced developmental apoptotic cell death in mouse cerebral cortex. Anesthesia and Analgesia 116(4), 2013.

Ward CG, Hughes E, Joseph B, Hofacer R, Choe YS, Danzer S, Loepke AW: Vulnerability to anesthetic-induced neuroapoptosis is determined by the maturational age of the cell and not the age of the animal. SPA/AAP Pediatric Anesthesiology 2012 Notes: Oral presentation during awards presentation.

Ward CG, Loepke AW: Anesthetics and sedatives: Toxic or protective for the developing brain? Pharmacological Research 2011.

Ward CG, Wei H: Multiples of minimal alveolar concentrations of volatile agents are not necessarily equipotent. Anesthesiology 114(1): 221-222, 2011.

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Last updated: 01/21/2016
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