David J. Margolis, MD, Ph.D

faculty photo
Gerald R. Lazarus Professor
Attending Physician, Department of Dermatology, University of Pennsylvania Medical Center
Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine
Member, University of Pennsylvania Cancer Center, University of Pennsylvania Medical Center
Member, Graduate Group in Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine
Director, Division of Dermatoepidemiology, Department of Dermatology, University of Pennsylvania Perelman School of Medicine
Member, Institute for Diabetes, Obesity and Metabolism (IDOM), University of Pennsylvania
Member, Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine
Member, Executive Committee, Clinical Epidemiology Unit, Department of Biostatistics and Epidemiology, University of Pennsylvania
Member, Junior Faculty Award Review Committee, University of Pennsylvania Perelman School of Medicine
Member and Chair (2014-2022), Committee on Appointments and Promotions, University of Pennsylvania School of Medicine
Executive Committee Director, Clinical Research Core, Department of Dermatology, University of Pennsylvania School of Medicine
Vice Chair of Faculty Affairs, Department of Dermatology
Department: Dermatology

Contact information
727 South Perelman Center for Advanced Medicine
3400 Civic Center BLVD
Department of Dermatology and Department of Biostatistics and Epidemiology
University of Pennsylvania
Philadelphia, PA 19104-4283
Office: 215-662-2590
Lab: 215-898-4938
Education:
B.A.
Wesleyan University, 1981.
M.D.
University of Chicago-Pritzker, 1985.
M.S.C.E. (Epidemiology)
University of Pennsylvania, 1998.
Ph.D. (Epidemiology)
University of Pennsylvania, 2000.
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Description of Research Expertise

epidemiology, clinical trials, pharmacoepidemiology, wound repair, chronic wounds

Description of Clinical Expertise

dermatology, chronic wounds

Selected Publications

Palepu S, Sindgi VM, Aylur KS, Margolis DJ, Kovarik C.: Mental Health and Substance Use Amongst Trans Women in India. J Homosex Mar 2025.

Grice EA, Brennan-Crispi D, Rodriguez N, Margolis DJ, Seykora JT, Cotsarelis G, Taylor SC, Shuda J.: Penn Academy for Skin Health (PASH): An Experiential Pipeline Program in Skin Biology and Dermatology for High-School Students. J Invest Dermatol 145(3): 478-480, Mar 2025.

Bibineyshvili Y, Vajtay TJ, Salsabilian S, Fliss N, Suvarnakar A, Fang J, Teng S, Alder J, Najafizadeh L, Margolis DJ.: Imaging the large-scale and cellular response to focal traumatic brain injury in mouse neocortex. Exp Physiol 110(2): 321-344, Feb 2025.

Barbieri JS, Ellenberg S, Grice E, Tierney A, VanderBeek SB, Papadopoulos M, Mason J, Mason A, Dattilo J, Margolis DJ.: Challenges in designing a randomized, double-blind noninferiority trial for treatment of acne: The SD-ACNE trial. Clin Trials 22(1): 66-76, Feb 2025.

Lydecker AD, Kim JJ, Robinson GL, Johnson JK, Brown CH, Petruccelli CC, Terrin ML, Margolis DJ, Roghmann MC.: Chlorhexidine vs Routine Foot Washing to Prevent Diabetic Foot Ulcers: A Randomized Clinical Trial. JAMA Netw Open 8(2): e2460087, Feb 2025.

Nouri Z, Biglari S, Tabatabaiefar MA, Vahidnezhad F, Hozhabrpour A, March ME, Margolis DJ, Gudjonsson JE, Hakonarson H, Vahidnezhad H.: Filaggrinopathies-FLG/FLG2: Diagnostic Complexities and Immunotherapy. J Invest Dermatol(24), Feb 2025.

Barbieri JS, Ellenberg SS, Tierney A, VanderBeek SB, Papadopoulos M, Mason J, Mason A, Dattilo J, Margolis DJ.: Establishing minimally important difference thresholds for lesion counts in acne clinical studies. J Am Acad Dermatol(25), Jan 2025.

Wong JJ, Margolis DJ.: Association Between Food Allergy Status and Atopic Dermatitis Control and Persistence: A Longitudinal Analysis of the Pediatric Eczema Elective Registry. Pediatr Dermatol Dec 2024.

Chiesa Fuxench ZC, Mitra N, Grice E, Hoffstad O, Margolis DJ.: Is seborrhoeic dermatitis of infancy and childhood related to maternal history of seborrhoeic dermatitis? A large population-based cohort study from the UK. Br J Dermatol 192(1): 72-77, Dec 2024.

Rosenthal BE, Schaubel DE, Lewis JD, Margolis DJ, Goldberg DS, Bittermann T.: Immunosuppression regimen and latitude impact keratinocyte carcinoma risk in U.S. liver transplant recipients. Arch Dermatol Res 316(9): 641, Sep 2024.

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Last updated: 04/23/2025
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