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David J. Margolis, MD, MSCE, Ph.D
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Gerald R. Lazarus Professor
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Attending Physician, Department of Dermatology, University of Pennsylvania Medical Center
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Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine
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Member, University of Pennsylvania Cancer Center, University of Pennsylvania Medical Center
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Member, Graduate Group in Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine
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Member, Institute for Diabetes, Obesity and Metabolism (IDOM), University of Pennsylvania
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Member, Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine
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Executive Committee Director, Clinical Research Core, Department of Dermatology, University of Pennsylvania School of Medicine
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Vice Chair of Faculty Affairs, University of Pennsylvania Department of Dermatology
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Department: Dermatology
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Graduate Group Affiliations
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Contact information
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727 South Perelman Center for Advanced Medicine
1f 3400 Civic Center BLVD
53 Department of Dermatology and Department of Biostatistics and Epidemiology
42 University of Pennsylvania
Philadelphia, PA 19104-4283
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1f 3400 Civic Center BLVD
53 Department of Dermatology and Department of Biostatistics and Epidemiology
42 University of Pennsylvania
Philadelphia, PA 19104-4283
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Office: 215-662-2590
3e Lab: 215-898-4938
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3e Lab: 215-898-4938
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Publications
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Education:
21 9 B.A. c
2c Wesleyan University, 1981.
21 9 M.D. c
37 University of Chicago-Pritzker, 1985.
21 d M.S.C.E. 19 (Epidemiology) c
33 University of Pennsylvania, 1998.
21 a Ph.D. 19 (Epidemiology) c
33 University of Pennsylvania, 2000.
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Permanent link21 9 B.A. c
2c Wesleyan University, 1981.
21 9 M.D. c
37 University of Chicago-Pritzker, 1985.
21 d M.S.C.E. 19 (Epidemiology) c
33 University of Pennsylvania, 1998.
21 a Ph.D. 19 (Epidemiology) c
33 University of Pennsylvania, 2000.
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Description of Research Expertise
61 epidemiology, clinical trials, pharmacoepidemiology, wound repair, chronic wounds65
Description of Clinical Expertise
2b dermatology, chronic wounds1a 29
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79 Meng S, Berna R, Hoffstad O, Takeshita J, Shin D, Chiesa Fuxench ZC, Margolis 96 DJ: Epithelial Barrier Diseases Among Adult Patients with Seborrheic Dermatitis. JAMA Dermatol 162(1): 15-23, Jan 2026.
de Palepu S, Sindgi VM, Aylur KS, Margolis DJ, Kovarik C.: Mental Health and Substance Use Amongst Trans Women in India. J Homosex 73(2): 485-493, 2026.
78 Nock MR, Ershadi S, Sánchez-Feliciano A, Amstutz AV, Margolis DJ, Pusic AL, 58 Barbieri JS: Measurement Properties of PROMIS Measures Relevant to Chronic Skin 54 Diseases. JAMA Dermatol Dec 2025 Notes: epub ahead of print.
79 Eager JM, Cortes-Troncoso J, Kalan L, Campbell A, Rao A, Weingarten MS, Grice 58 EA, Oropallo A, Margolis DJ, Sacan A, Spiller KL.: Differential Gene Expression 48 in Healing and Non-Healing Diabetic Foot Ulcers and Discovery of Novel 71 Ratiometric Biomarker to Predict Healing Outcome. Wound Repair Regen 33(6), Nov-Dec 2025.
f1 Meng S, Berna R, Takeshita J, Hoffstad O, Shin D, Mitra N, Margolis DJ: Bidirectional Associations Between Seborrheic Dermatitis and Epithelial Barrier Diseases: A Retrospective Cohort Study 45 Allergy Oct 2025 Notes: epub ahead of print.
77 O'Hara LM, Lydecker AD, Robinson GL, O'Hara NN, Kim JJ, Littman AJ, Schmidt 29 BM, Addison O, Margolis DJ, Roghmann MC 2d : Understanding Patient Preferences 4f Regarding Limb Salvage for Diabetic Foot Ulcers: A Discrete Choice Experiment 42 Diabetes Care 48(9): 1517-1523, Sep 2025.
162 Barbieri JS, Ellenberg SS, Tierney A, VanderBeek SB, Papadopoulos M, Mason J, Mason A, Dattilo J, Margolis DJ.: Establishing minimally important difference thresholds for lesion counts in acne clinical studies. J Am Acad Dermatol 92(5): 1117-1119, May 2025 Notes: Epub 2025 Jan 15.
71 Choi JS, Kumar M, Wilson AR, Mathew-Steiner SS, Singh K, Margolis DJ, 16 Schleyer TKL, Sen CK 70 : Multistate Model of Chronic Wounds, Amputations, and Mortality: Cohort Study of a State-wide Registry 46 Ann Surg May 2025 Notes: Epub ahead of print.
13c Wong JJ, Margolis DJ.: Association Between Food Allergy Status and Atopic Dermatitis Control and Persistence: A Longitudinal Analysis of the Pediatric Eczema Elective Registry. Pediatr Dermatol 42(3): 552-555, May 2025 Notes: Epub 2024 Dec 10.
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Selected Publications
11a Cohen LS, Adeuyan O, Margolis DJ, Kim EJ, Chung J: Medicare coverage of home phototherapy units for cutaneous T-cell lymphoma versus psoriasis. J Am Acad Dermatol 94(2): 693-695, Feb 2026 Notes: Epub 2025 Oct.79 Meng S, Berna R, Hoffstad O, Takeshita J, Shin D, Chiesa Fuxench ZC, Margolis 96 DJ: Epithelial Barrier Diseases Among Adult Patients with Seborrheic Dermatitis. JAMA Dermatol 162(1): 15-23, Jan 2026.
de Palepu S, Sindgi VM, Aylur KS, Margolis DJ, Kovarik C.: Mental Health and Substance Use Amongst Trans Women in India. J Homosex 73(2): 485-493, 2026.
78 Nock MR, Ershadi S, Sánchez-Feliciano A, Amstutz AV, Margolis DJ, Pusic AL, 58 Barbieri JS: Measurement Properties of PROMIS Measures Relevant to Chronic Skin 54 Diseases. JAMA Dermatol Dec 2025 Notes: epub ahead of print.
79 Eager JM, Cortes-Troncoso J, Kalan L, Campbell A, Rao A, Weingarten MS, Grice 58 EA, Oropallo A, Margolis DJ, Sacan A, Spiller KL.: Differential Gene Expression 48 in Healing and Non-Healing Diabetic Foot Ulcers and Discovery of Novel 71 Ratiometric Biomarker to Predict Healing Outcome. Wound Repair Regen 33(6), Nov-Dec 2025.
f1 Meng S, Berna R, Takeshita J, Hoffstad O, Shin D, Mitra N, Margolis DJ: Bidirectional Associations Between Seborrheic Dermatitis and Epithelial Barrier Diseases: A Retrospective Cohort Study 45 Allergy Oct 2025 Notes: epub ahead of print.
77 O'Hara LM, Lydecker AD, Robinson GL, O'Hara NN, Kim JJ, Littman AJ, Schmidt 29 BM, Addison O, Margolis DJ, Roghmann MC 2d : Understanding Patient Preferences 4f Regarding Limb Salvage for Diabetic Foot Ulcers: A Discrete Choice Experiment 42 Diabetes Care 48(9): 1517-1523, Sep 2025.
162 Barbieri JS, Ellenberg SS, Tierney A, VanderBeek SB, Papadopoulos M, Mason J, Mason A, Dattilo J, Margolis DJ.: Establishing minimally important difference thresholds for lesion counts in acne clinical studies. J Am Acad Dermatol 92(5): 1117-1119, May 2025 Notes: Epub 2025 Jan 15.
71 Choi JS, Kumar M, Wilson AR, Mathew-Steiner SS, Singh K, Margolis DJ, 16 Schleyer TKL, Sen CK 70 : Multistate Model of Chronic Wounds, Amputations, and Mortality: Cohort Study of a State-wide Registry 46 Ann Surg May 2025 Notes: Epub ahead of print.
13c Wong JJ, Margolis DJ.: Association Between Food Allergy Status and Atopic Dermatitis Control and Persistence: A Longitudinal Analysis of the Pediatric Eczema Elective Registry. Pediatr Dermatol 42(3): 552-555, May 2025 Notes: Epub 2024 Dec 10.
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