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John Y.K. Lee, M.D.

John Y.K. Lee, M.D.

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Assistant Professor of Neurosurgery at the Pennsylvania Hospital
Department: Neurosurgery

Contact information
Department of Neurosurgery
Pennsylvania Hospital
Washington Square West Building
235 S. 8th Street
Philadelphia, PA 19106
Office: 215-829-5189
Fax: 215-829-6645
B.S. (Molecular Biophysics and Biochemistry)
Yale University, 1994.
Rutgers - Robert Wood Johnson Medical School, New Jersey, 1998.
M.S.C.E. (Clinical Epidemiology - candidate)
University of Pennsylvania, 2015.
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Description of Clinical Expertise

Dr. Lee has a passion for minimally invasive ways to treat brain and skull base tumors. This passion is expressed as a commitment to endoscopic approaches to remove pituitary, clival, acoustic neuromas and other skull-base tumors. Another expression of his interest in minimally invasive methods is his devotion to stereotactic radiosurgery, eg. "incision-less" brain surgery.

In addition to brain tumors, Dr. Lee is committed to the comprehensive treatment of patients with craniofacial neuralgias, including trigeminal neuralgia, glossopharyngeal neuralgia, and hemifacial spasm. Dr. Lee uses minimally invasive, fully endoscopic surgical procedures including microvascular decompression (Jannetta procedure) and stereotactic radiosurgery to cure these disorders.

Selected Publications

Learned KO, Adappa ND, Lee JYK, Newman JG, Palmer JN, Loevner LA: MR imaging evolution of endoscopic cranial defect reconstructions using nasoseptal flaps and their distinction from neoplasm. American Journal of NeuroRadiology 35(6): 1182-9, June 2014.

Sheehan JP, Starke RM, Kano H, Kaufmann AM, Mathieu D, Zeiler FA, West M, Chao ST, Varma G, Chiang VL, Yu JB, McBride HL, Nakaji P, Youssef E, Honea N, Rush S, Kondziolka D, Lee JY, Bailey RL, Kunwar S, Petti P, Lunsford LD: Gamma Knife radiosurgery for sellar and parasellar meningiomas: a multicenter study. Journal of Neurosurgery 120(6): 1268-77, June 2014.

Lee JYK, Bohman L, Bergsneider M: Contemporary Neurosurgical Techniques for Pituitary Tumor Resection. J Neurooncology 117(3): 437-444, May 2014.

Learned KO, Mohan S, Hyder IZ, Bagley LJ, Wang S, Lee JYK: Imaging Features of a Gelatin-Thrombin Matrix Hemostatic Agent in the Intracranial Surgical Bed: A Unique Space-Occupying Pseudomass. American Journal of Neuroradiology 35(4): 686-90, April 2014.

Ali ZS, Bailey RL, Daniels LB, Vakhshori V, Lewis DJ, Hossain AT, Sitterley KY, Lee JY, Storm PB, Heuer GG, Stein SC: Comparative effectiveness of treatment options for pediatric craniopharyngiomas. J Neurosurg Pediatr 13(2): 178-88, Feb 2014.

Brastianos PK, Taylor-Weiner A, Manley PE, Jones RT, Dias-Santagata D, Thorner AR, Lawrence MS, Rodriguez FJ, Bernardo LA, Schubert L, Sunkavalli A, Shillingford N, Calicchio ML, Lidov HG, Taha H, Martinez-Lage M, Santi M, Storm PB, Lee JY, Palmer JN, Adappa ND, Scott RM, Dunn IF, Laws ER Jr, Stewart C, Ligon KL, Hoang MP, Van Hummelen P, Hahn WC, Louis DN, Resnick AC, Kieran MW, Getz G, Santagata S.: Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. Nature Genetics 46(2): 161-5, Feb 2014.

Goodwin CR, Yang JX, Bettegowda C, Hwang B, James C, Biser A, Raza S, Bender M, Carson B, Lee JY, Lim M: Glycerol rhizotomy via a retrosigmoid approach as an alternative treatment for trigeminal neuralgia. Clinical Neurology and Neurosurgery. Elsevier, 115(12): 2454–2456, December 2013.

Ali Zarina S, Lang Shih-Shan, Kamat Ameet R, Adappa Nithin D, Palmer James N, Storm Phillip B, Lee John Y K: Suprasellar pediatric craniopharyngioma resection via endonasal endoscopic approach. Child's Nervous System 29(11): 2065-70, November 2013.

Halpern CH, Lang SS, Lee JY.: Fully endoscopic microvascular decompression: our early experience. Minimally Invasive Surgery. Joachim Oertel (eds.). September 2013 Notes: doi: 10.1155/2013/739432. Epub 2013 Sep 3.

Sheehan JP, Starke RM, Mathieu D, Young B, Sneed PK, Chiang VL, Lee JYK, Kano H, Park KJ, Niranjan A, Kondziolka D, Barnett GH, Rush S, Golfinos JG, Lunsford LD: Gamma Knife radiosurgery for the management of nonfunctioning pituitary adenomas: a multicenter study. Journal of Neurosurgery 119(2): 446-56, August 2013.

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Last updated: 08/06/2014
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