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Perelman School of Medicine at the University of Pennsylvania Advanced Search

Michael Chorny, PhD

Michael Chorny, PhD

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Research Assistant Professor of Pediatrics
Department: Pediatrics

Contact information
The Abramson Pediatric Research Center, Suite 702G
The Children's Hospital of Philadelphia
3615 Civic Center Blvd.
Philadelphia, PA 19104
Office: 215-590-3063
Education:
BPharm (Pharmaceutical sciences)
The Hebrew University of Jerusalem, Israel, 1996.
MS (Pharmaceutical sciences)
The Hebrew University of Jerusalem, Israel, 1997.
PhD (Pharmaceutical sciences)
The Hebrew University of Jerusalem, Israel, 2004.
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Selected Publications

M. Howard, E. Hood, C. Greineder, I. Alferiev, M. Chorny, V. Muzykantov: Targeting to endothelial cells augments the protective effect of novel dual bioactive antioxidant/anti-inflammatory nanoparticles. Molecular Pharmaceutics 11(7): 2262-2270, July 2014.

E.D. Hood, M. Chorny, C.F. Greineder, I.S. Alferiev, .J. Levy, V.R. Muzykantov: Endothelial targeting of nanocarriers loaded with antioxidant enzymes for protection against vascular oxidative stress and inflammation Biomaterials 35(11): 3708-3715, Apr 2014.

J.E. Tengood, I.S. Alferiev, K. Zhang, I. Fishbein, R.J. Levy, M. Chorny: Real-time analysis of composite magnetic nanoparticle disassembly in vascular cells and biomimetic media. Proceedings of the National Academy of Sciences of the United States of America 111(11): 4245–4250, March 2014.

I. Fishbein, S.P. Forbes, R.F. Adamo, M. Chorny, R.J. Levy, I.S. Alferiev: Vascular gene transfer from metallic stent surfaces using adenoviral vectors tethered through hydrolysable cross-linkers. Journal of Visualized Experiments In Press, 2014.

I. Fishbein, S.P. Forbes, M. Chorny, J.M. Connolly, R.F. Adamo, R.A. Corrales, I.S.Alferiev, R.J. Levy : Adenoviral vector tethering to metal surfaces via hydrolyzable cross-linkers for the modulation of vector release and transduction. Biomaterials 34(28): 6938-48, Sep 2013.

M. Chorny, I. Fishbein, J.E. Tengood, R.F. Adamo, I.S. Alferiev, R.J. Levy: Site-specific gene delivery to stented arteries using magnetically guided zinc oleate-based nanoparticles loaded with adenoviral vectors. The FASEB Journal 27: 2198-2206, Jun 2013.

E. Branchetti, R. Sainger, P. Poggio, J.B. Grau, J. Patterson-Fortin, J.E. Bavaria, M. Chorny, E. Lai, R.C. Gorman, R.J. Levy, G. Ferrari: Antioxidant Enzymes Reduce DNA Damage and Early Activation of Valvular Interstitial Cells in Aortic Valve Sclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology 33(2): e66-74, Feb 2013.

S.P. Forbes, I.S. Alferiev, M. Chorny, R.F. Adamo, R.J. Levy, I. Fishbein: Modulation of NO and ROS production by AdiNOS transduced vascular cells through supplementation with L-Arg and BH4: Implications for gene therapy of restenosis. Atherosclerosis 230: 23-32, 2013.

M. Chorny, I.S. Alferiev, I. Fishbein, J.E. Tengood, Z. Folchman-Wagner, S.P. Forbes, R.J. Levy: Formulation and in vitro characterization of composite biodegradable magnetic nanoparticles for magnetically guided cell delivery. Pharmaceutical Research 29(5): 1232-1241, May 2012.

M. Chorny*, E. Hood*, R.J. Levy, V.R. Muzykantov : Endothelial delivery of antioxidant enzymes loaded into non-polymeric magnetic nanoparticles. Journal of Controlled Release 146(1): 144-51, Aug 2010.

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Last updated: 07/21/2014
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