Chris T Derk, MD, MS
Professor of Clinical Medicine (Rheumatology)
Department: Medicine
Contact information
Division of Rheumatology
3400 Spruce Street
5th Floor White Bldg
Philadelphia, PA 19104
3400 Spruce Street
5th Floor White Bldg
Philadelphia, PA 19104
Office: 215-662-2792
Fax: 215-662-4500
Fax: 215-662-4500
Publications
Education:
AA
Harrisburg Area Community College, 1988.
BS (Pre-Medicine)
Pennsylvania State University, 1990.
MD
Thomas Jefferson University, 1994.
MS (Pharmacology)
Thomas Jefferson University, 2006.
Permanent linkAA
Harrisburg Area Community College, 1988.
BS (Pre-Medicine)
Pennsylvania State University, 1990.
MD
Thomas Jefferson University, 1994.
MS (Pharmacology)
Thomas Jefferson University, 2006.
Description of Clinical Expertise
Systemic Sclerosis (Scleroderma) and other fibrotic autoimmune connective tissue disorders ( Eosinophilic Faciitis, Scleromyxedema, Scleredema, Nephrogenic Systemic Fibrosis). Raynaud's phenomenon. Systemic Lupus Erythematosus.Description of Other Expertise
Rheumatology based educational models.Description of Research Expertise
Scleroderma and related diseases clinical outcomes, therapeutic interventions and disease pathogenesis. Systemic Lupus Erythematosus clinical outcomes.Selected Publications
Luo Y, Gordon J, Xu J, Kolstad KD, Chung L, Steen VD, Bernstein EJ, PHAROS Investigators: Prognostic significance of pericardial effusion in systemic sclerosis-associated pulmonary hypertension: analysis from the PHAROS registry. Rheumatology kead368, July 2023.Basyal B; Ullah W; Derk CT: Pericardial effusions and Cardiac Tamponade in hospitalized systemic sclerosis patients: analysis of the national inpatient sample. BMC Rheumatol 7(1): 34, 2023.
Bean MB, Derk CT: Lower Extremity ulcers in patients with systemic sclerosis. Open J Rheumatol Autoimmune Dis 12(1): 35-45, Feb 2022.
GRASP study group: Functional NOTCH4 Variants Increase Notch Signaling and susceptibility for systemic sclerosis. American College of Rheumatology Annual Scientific meeting 2022 Notes: Poster.
Khanna D, Caldron P, Martin RW, Kafaja S, Spiera R, Shahouri S, Shah A, Hsu V, Ervin J, Simms R, Domsic RT, Steen V, Hummers LK, Derk C, Mayes M, Chatterjee S, Varga J, Kesten S, Draser JK, Furst DE: Adipose-derived regenerative cell transplantation for the treatment of hand dysfunction in systemic sclerosis: a randomized clinical trial Arthritis Rheumatol 74(8): 1399-1408, 2022.
GRASP study group: Genome-wide association study in African American systemic sclerosis patients identifies a novel target-transforming growth factor -beta 3 (TGF beta 3) American College of Rheumatology Annual Scientific meeting 2022 Notes: Oral.
GRASP study group: Systemic Sclerosis-associated class II HLA alleles restrict the diversity of the CDR3 and the T cell receptor repertoire in African American patients. American College of Rheumatology Annual scientific meeting 2022 Notes: Poster.
Minalyan A, Gabrielyan L, Khanal S, Basyal B, Derk CT : Systemic Sclerosis : Current state and survival after lung transplantation Cureus 13(1): e12797, Jan 2021.
Sandorf N, Derk CT, Hajnoczky N: Long term outcomes of vascular grafting of medium sized vessels of the wrist and hand in patients with medication refractory systemic sclerosis related Raynaud's phenomenon at the University of Pennsylvania from 2009-2019. American College of Rheumatology Annual scientific meeting 2021 Notes: Poster.
Basyal B, Bhandari B, Derk CT: Avascular necrosis in systemic sclerosis patients: a case-based review of demographics, presentation, and management. Clin Rheumatol 40(1): 399-405, 2021.