Chris T Derk, MD, MS
Professor of Clinical Medicine (Rheumatology)
Department: Medicine
Contact information
Division of Rheumatology
3400 Spruce Street
5th Floor White Bldg
Philadelphia, PA 19104
3400 Spruce Street
5th Floor White Bldg
Philadelphia, PA 19104
Office: 215-662-2792
Fax: 215-662-4500
Fax: 215-662-4500
Publications
Education:
AA
Harrisburg Area Community College, 1988.
BS (Pre-Medicine)
Pennsylvania State University, 1990.
MD
Thomas Jefferson University, 1994.
MS (Pharmacology)
Thomas Jefferson University, 2006.
Permanent linkAA
Harrisburg Area Community College, 1988.
BS (Pre-Medicine)
Pennsylvania State University, 1990.
MD
Thomas Jefferson University, 1994.
MS (Pharmacology)
Thomas Jefferson University, 2006.
Description of Clinical Expertise
Systemic Sclerosis (Scleroderma) and other fibrotic autoimmune connective tissue disorders ( Eosinophilic Faciitis, Scleromyxedema, Scleredema, Nephrogenic Systemic Fibrosis). Raynaud's phenomenon. Systemic Lupus Erythematosus.Description of Research Expertise
Scleroderma (Systemic Sclerosis) and related diseases clinical outcomes, therapeutic interventions and disease pathogenesis.Selected Publications
Mehmetoglu E, Mummadisetty A, Chatzitofis A, Parperis K, Sandorfi N, Derk CT: A systematic review of prevalence and predictors of depression in systemic sclerosis based on the CES-D, BDI and PHQ-9 self-assessment questionnaires. Clin Rheumatol April 2025.Aguila T, Madan R, Palmer MB, Derk CT: Zebra bodies in kidney biopsy: Drug-induced phospholipidosis in patient with Systemic Lupus Erythematosus. J Rheumatol March 2025.
Parperi K, Costi E, Philippou S, Hadi M, Derk CT: Efficacy of disease modifying antirheumatic drugs in the treatment of granulomatous mastitis: a systematic review. Rheumatol Int 44(11): 2371-79, Nov 2024.
GRASP study group: Rare variants in the IL1RAP gene implicate the IL-1 signaling pathway in the pathogenesis of systemic sclerosis in African and European ancestries. ACR annual scientific meeting, Washington DC 2024.
Ross L, Hansen D, Proudman S, Khanna D, Herrick AL, Stevens W, Australian Scleroderma Interest Group (ASIG), Canadian Scleroderma Research Group (CSRG), Baron M, Nikpour M, SCTC Activity Index Working Group: Development and initial validation of the novel Scleroderma Clinical Trials Consortium Activity Index. Arthritis Rheumatol 2024.
GRASP study group: Admixture mapping and gene-based analysis identifies rare variants in genes in the IL-13 and TGF beta signaling pathways in African Americans with systemic sclerosis. ACR annual scientific meeting, Washington DC 2024.
GRASP study Group: TCR motifs identify unique clones in African Americans with systemic sclerosis ACR annual Scientific meeting, Washington DC 2024.
Luo Y, Gordon J, Xu J, Kolstad KD, Chung L, Steen VD, Bernstein EJ, PHAROS Investigators: Prognostic significance of pericardial effusion in systemic sclerosis-associated pulmonary hypertension: analysis from the PHAROS registry. Rheumatology kead368, July 2023.
Basyal B; Ullah W; Derk CT: Pericardial effusions and Cardiac Tamponade in hospitalized systemic sclerosis patients: analysis of the national inpatient sample. BMC Rheumatol 7(1): 34, 2023.
Bean MB, Derk CT: Lower Extremity ulcers in patients with systemic sclerosis. Open J Rheumatol Autoimmune Dis 12(1): 35-45, Feb 2022.