Chris T Derk, MD, MS
Professor of Clinical Medicine (Rheumatology)
Department: Medicine
Contact information
Division of Rheumatology
3400 Spruce Street
5th Floor White Bldg
Philadelphia, PA 19104
3400 Spruce Street
5th Floor White Bldg
Philadelphia, PA 19104
Office: 215-662-2792
Fax: 215-662-4500
Fax: 215-662-4500
Publications
Education:
AA
Harrisburg Area Community College, 1988.
BS (Pre-Medicine)
Pennsylvania State University, 1990.
MD
Thomas Jefferson University, 1994.
MS (Pharmacology)
Thomas Jefferson University, 2006.
Permanent linkAA
Harrisburg Area Community College, 1988.
BS (Pre-Medicine)
Pennsylvania State University, 1990.
MD
Thomas Jefferson University, 1994.
MS (Pharmacology)
Thomas Jefferson University, 2006.
Description of Clinical Expertise
Systemic Sclerosis (Scleroderma) and other fibrotic autoimmune connective tissue disorders ( Eosinophilic Faciitis, Scleromyxedema, Scleredema, Nephrogenic Systemic Fibrosis). Raynaud's phenomenon. Systemic Lupus Erythematosus.Description of Research Expertise
Scleroderma (Systemic Sclerosis) and related diseases clinical outcomes, therapeutic interventions and disease pathogenesis.Selected Publications
Mehmetoglu E, Mummadisetty A, Chatzitofis A, Parperis K, Sandorfi N, Derk CT: A systematic review of prevalence and predictors of depression in systemic sclerosis based on the CES-D, BDI and PHQ-9 self-assessment questionnaires. Clin Rheumatol April 2025.Hajnoczky N, Levin LS, Sandorfi N, Derk CT: Long-term outcomes of vascular grafting of medium-sized vessels of wrist and hand in systemic sclerosis patients with medication refractory Raynaud's. J Scleroderma Relat Disord April 2025.
Parperis K, Papachristodoulou M, Derk C, Psarelis S, Voskarides K, Chatzittofis A. : Post-traumatic stress disorder and systemic lupus erythematosus: insights from a systematic review. Rheumatology April 2025.
Aguila T, Madan R, Palmer MB, Derk CT: Zebra bodies in kidney biopsy: Drug-induced phospholipidosis in patient with Systemic Lupus Erythematosus. J Rheumatol March 2025.
Papchristodoulou E; Kakkoulis L; Chopra R; Derk CT, Parperis K: Clinical Features and Treatment Outcomes in Aseptic Abscess Syndrome: A Systematic Review of 104 Cases. ACR Convergence 2025.
GRASP study group: Functional NOTCH4 Variants Drive Vasculopathy and Fibrosis in Systemic Sclerosis. ACR Convergence 2025.
Parperi K, Costi E, Philippou S, Hadi M, Derk CT: Efficacy of disease modifying antirheumatic drugs in the treatment of granulomatous mastitis: a systematic review. Rheumatol Int 44(11): 2371-79, Nov 2024.
GRASP study group: Rare variants in the IL1RAP gene implicate the IL-1 signaling pathway in the pathogenesis of systemic sclerosis in African and European ancestries. ACR annual scientific meeting, Washington DC 2024.
GRASP study group: Admixture mapping and gene-based analysis identifies rare variants in genes in the IL-13 and TGF beta signaling pathways in African Americans with systemic sclerosis. ACR annual scientific meeting, Washington DC 2024.
GRASP study Group: TCR motifs identify unique clones in African Americans with systemic sclerosis ACR annual Scientific meeting, Washington DC 2024.