Chris T Derk, MD, MS

faculty photo
Associate Professor of Clinical Medicine
Department: Medicine

Contact information
Division of Rheumatology
300 S Atrium
PCAM Bldg
3400 Spruce street
Philadelphia, PA 19104
Office: 215-662-2792
Fax: 215-662-4500
Education:
AA
Harrisburg Area Community College, 1988.
BS (Pre-Medicine)
Pennsylvania State University, 1990.
MD
Thomas Jefferson University, 1994.
MS (Pharmacology)
Thomas Jefferson University, 2006.
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Description of Clinical Expertise

Systemic Sclerosis (Scleroderma) and other fibrotic autoimmune connective tissue disorders ( Eosinophilic Faciitis, Scleromyxedema, Scleredema, Nephrogenic Systemic Fibrosis). Raynaud's phenomenon. Systemic Lupus Erythematosus.

Description of Other Expertise

Rheumatology based educational models.

Description of Research Expertise

Scleroderma and related diseases clinical outcomes, therapeutic interventions and disease pathogenesis. Systemic Lupus Erythematosus clinical outcomes.

Selected Publications

A. Schorpion, M. Shenin, R. Neubauer, C.T. Derk: An open-label study of ambrisentan with anti-fibrotic agent combination therapy in the treatment of diffuse systemic sclerosis. EULAR June 2017.

Chung L, Fairchild RM, Furst DE, Li S, Alkassab F, Bolster MB, Csuka ME, Derk CT, Domsick RT, Fischer A, Frech T, Gomberg-Maitland M, Gordon JK, Hitchcliff M, Hsu V, Hummers LK, Khanna D, Medsger TA, Molitor JA, Preston IR, Schiopu E, Shapiro L, Hant F, Silver R, Simms R, Varga J, Steen VD, Zamanian RT: Utility of B-type natriuretic peptides in the assessment of patients with systemic sclerosis-associated pulmonary hypertension in the PHAROS registry. Clin Exp Rheumatol November 2016.

Grewal SK, DErk CT, Rosenbach M: Ulcers of the ventral aspect of fingers. JAMA Dermatol 152(10): 1157-58, October 2016.

Sehra ST, Kelly A, Baker JF, Derk CT: Predictors of inpatient mortality in patients with systemic sclerosis: a case control study. Clinical Rheumatology 35(6): 1631-5, Jun 2016.

Khanna D, Denton CP, Merkel PA, Krieg T, Le Brun FO, Marr A, Papadakis K, Pope J, Mattuci-Cerinic M, Furst DE, DUAL-1 investigators, DUAL-2 investigators: Effect of Macitentan on the development of new ischemic digital ulcers in Patients with Systemic Sclerosis: DUAL-1 and DUAL-2 randomized clinical trials. JAMA 315(18): 1975-88, May 2016.

Hinchcliff M, Khanna S, Hsu VM, Lee J, Almagor O, Chang RW, Steen V, Chung L, PHAROS investigators: Survival in systemic sclerosis-pulmonary arterial hypertension by serum autoantibody status in the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma (PHAROS) Registry. Seminar of Arthritis and Rheumatology 45(3): 309-14, Dec 2015.

Kelly, A; Derk CT: Anti-RNA polymerase III antibodies in Systemic Sclerosis. Open Journal of Rheumatology and Autoimmune Diseases 5: 81-86, Aug 2015.

Abraham M, Derk CT: Anti-Ribosomal- P antibodies in lupus nephritis, neuropsychiatric lupus, lupus hepatitis and Chaga's disease: promising yet limited in clinical utility. Rheumatol Int 35(1): 27-33, Jan 2015.

Sehra, S; Kelly, A, Baker J, Derk CT: Predictors of inpatient mortality in patient with systemic sclerosis: a case control study. American College of Rheumatology, Annual Scientific Meeting, Boston. Poster Presentation Nov 2014.

Mecoli C, Purohit S, Sandorfi N, Derk CT: Mortality, Recurrence, and hospital course of patients with systemic sclerosis-related acute intestinal pseudo-obstruction. J Rheumatol 41(10): 2049-54, Oct 2014.

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Last updated: 05/13/2017
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