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Benjamin L. Prosser, Ph.D

Benjamin L. Prosser, Ph.D

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Assistant Professor of Physiology
Department: Physiology

Contact information
Clinical Research Building Rm 726
415 Curie Blvd.
Philadelphia, PA 19104
Office: 215-746-1488
Education:
BS (Health and Exercise Science)
Wake Forest University, 2005.
Ph.D (Molecular Medicine)
University of Maryland School of Medicine, 2009.
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Description of Research Expertise

cardiac electrophysiology
excitation-contraction coupling
calcium signaling
mechanotransduction
redox signaling

Selected Publications

Ward Christopher W, Prosser Benjamin L, Lederer W Jonathan: Mechanical stretch induced activation of ROS/RNS signaling in striated muscle. Antioxidants & redox signaling Jan 2014.

Prosser Benjamin L, Ward Christopher W: Mechano-chemo transduction tunes the heartstrings. Science signaling 7(317): pe7, 2014.

Prosser Benjamin L, Ward Christopher W, Lederer W Jonathan: X-ROS signalling is enhanced and graded by cyclic cardiomyocyte stretch. Cardiovascular research 98(2): 307-14, May 2013.

Prosser Benjamin L, Khairallah Ramzi J, Ziman Andrew P, Ward Christopher W, Lederer W J: X-ROS signaling in the heart and skeletal muscle: stretch-dependent local ROS regulates [Ca²⁺]i. Journal of molecular and cellular cardiology 58: 172-81, May 2013.

Prosser BL: Rate-dependent X-ROS signaling in cardiac ventricular myocytes. Biophysical Society 57th Annual Meeting. Philadelphia, PA. February 2013.

Greiser M, Prosser BL, Khairallah RJ, Ward CW, Lederer WJ. : Atrial specific stretch-dependent sub-cellular Ca2+ signaling. 57th Annual Biophysical Society Meeting. Philadelphia, PA. February 2013. 2013.

Ward CW, Shi G, Prosser BL, Lederer WJ, Khairallah RJ. : Increased microtubule network stability underlies X-ROS in dystrophic skeletal muscle. 57th Annual Biophysical Society Meeting. Philadelphia, PA. 2013.

Khairallah Ramzi J, Shi Guoli, Sbrana Francesca, Prosser Benjamin L, Borroto Carlos, Mazaitis Mark J, Hoffman Eric P, Mahurkar Anup, Sachs Fredrick, Sun Yezhou, Chen Yi-Wen, Raiteri Roberto, Lederer W Jonathan, Dorsey Susan G, Ward Christopher W: Microtubules underlie dysfunction in duchenne muscular dystrophy. Science signaling 5(236): ra56, Aug 2012.

Prosser BL: Stretch-dependent X-ROS signaling. Biophysical Society 56th Annual Meeting. San Diego, CA. February 2012.

Khairallah RJ, Sbrana F, Shi G, Tedesco M, Prosser BL, Raiteri R, Lederer WJ, Ward CW. : Microtubule dependent mechanotransduction drives oxidative stress and calcium dysregulation in dystrophic skeletal muscle. 56th Annual Biophysical Society Meeting. San Diego, CA. 2012.

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Last updated: 04/17/2014
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