Hillary C.M. Nelson, Ph.D, M.P.H.
Hillary C.M. Nelson, Ph.D, M.P.H.
Associate Professor of Biochemistry and Biophysics
Department: Biochemistry and Biophysics
Graduate Group Affiliations
Contact information
Department of Biochemistry and Biophysics
813A Stellar-Chance
422 Curie Blvd
Philadelphia, PA 19104-6059
813A Stellar-Chance
422 Curie Blvd
Philadelphia, PA 19104-6059
Office: (215) 573-7473
Email:
HNELSON@MAIL.MED.UPENN.EDU
HNELSON@MAIL.MED.UPENN.EDU
Publications
Education:
BS (Molecular Biochemistry and Biophysics)
Yale University, 1979.
PhD (Biology (Biochemistry))
Massachusetts Institute of Technology, 1985.
MPH (Public health policy)
Perelman School of Medicine, University of Pennsylvania, 2011.
Permanent linkBS (Molecular Biochemistry and Biophysics)
Yale University, 1979.
PhD (Biology (Biochemistry))
Massachusetts Institute of Technology, 1985.
MPH (Public health policy)
Perelman School of Medicine, University of Pennsylvania, 2011.
Description of Other Expertise
Public Health -Interested in how science impacts public health policy
Interned with HHS in the summer of 2010, working on health reform bill
Capstone thesis on how the FDA regulated antibiotics for food-producing animals
Science and grant writing -
Experience in teaching a writing course to post-doctoral fellows, as well as a grant-writing course to CAMB pre-dissertation students
Teach science writing to BMB students
Administer an internal study section for the Department of Biochemistry and Biophysics
Responsible Conduct of Research education -
Worked with BGS to update RCR training. Participate in RCR training for BGS graduate students, PREP post-baccalaureate students, and BGS summer undergraduate interns
Selected Publications
Conlin, L.C. and Nelson, H.C.M: Trehalose affects the transcriptional activity of yeast heat shock transcription factor. Mol. Cell. Biol 27: 1505-1515, 2007.Eastmond, D.L. and Nelson, H.C.M. : Genome-wide analysis reveals new roles for the activation domains of the saccharomyces cerevisiae heat shock transcription factor (Hsf1) during the transient heat shock respons. J. Biol. Chem. 281: 32909-32921, 2006.
Ferguson, S.B., Anderson, E.S., Harshaw, R.B., Thate, T., Craig, N.L., and Nelson, H.C.M. : Protein Kinase A Regulates Constitutive Expression of Small Heat-Shock Genes in an Msn2/4p-Independent and Hsf1p-Dependent Manner in Saccharomyces cerevisiae. Genetics. Fred Winston (eds.). 169: 1203-1214, 2005.
Dashnau, J.L., Conlin, L.K., Nelson, H.C., and Vanderkooi, J.M. : Water structure in vitro and within Saccharomyces cerevisiae yeast cells under conditions of heat shock. Biochimica et Biophysica Acta 1780: 41-50, 2008.
Littlefield O., Nelson HC.: A new use for the 'wing' of the 'winged' helix-turn-helix motif in the HSF-DNA cocrystal. Nature Structural Biology 6(5): 464-70, May 1999.
Wyman C., Grotkopp E., Bustamante C., Nelson HC.: Determination of heat-shock transcription factor 2 stoichiometry at looped DNA complexes using scanning force microscopy. EMBO Journal 14(1): 117-23, Jan 3 1995.
Harrison, C.J., Bohm, A.A., and Nelson, H.C.M: Crystal structure of the DNA binding domain of the heat shock transcription factor. Science 263: 224-227, 1994.
Sorger PK., Nelson HC.: Trimerization of a yeast transcriptional activator via a coiled-coil motif. Cell 59(5): 807-13, Dec 1 1989.
Nelson HC., Finch JT., Luisi BF., Klug A.: The structure of an oligo(dA).oligo(dT) tract and its biological implications. Nature 330(6145): 221-6, Nov 19-25 1987.
Nelson HC., Sauer RT.: Lambda repressor mutations that increase the affinity and specificity of operator binding. Cell 42(2): 549-58, Sep 1985.