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Hillary C.M. Nelson, PhD, MPH

Hillary C.M. Nelson, PhD, MPH

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Associate Professor of Biochemistry and Biophysics
Department: Biochemistry and Biophysics
Graduate Group Affiliations

Contact information
Department of Biochemistry and Biophysics
813A Stellar-Chance
422 Curie Blvd
Philadelphia, PA 19104-6059
Office: 215-573-7473
BS (Molecular Biochemistry and Biophysics)
Yale University, 1979.
PhD (Biology (Biochemistry))
Massachusetts Institute of Technology, 1985.
Perelman School of Medicine, University of Pennsylvania, 2011.
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Description of Other Expertise

Public Health -
How science impacts public health policy
Affordable Care Act
Antibiotic Use in Food-Producing Animals
* Currently working to implement EBPH into the MPH curriculum *

Science and grant writing -
Teach science writing to BMB students in their pre-prelim grant writing course, with the philosophy of learning how to revise one's writing in light of how the reader perceives it
Administer an internal study section for the Department of Biochemistry and Biophysics to help bolster success of external funding
Edit faculty grants destined for NIH and other funding agencies in order to strengthen clarity, logic, and readability

Selected Publications

Conlin, L.C. and Nelson, H.C.M: Trehalose affects the transcriptional activity of yeast heat shock transcription factor. Mol. Cell. Biol 27: 1505-1515, 2007.

Eastmond, D.L. and Nelson, H.C.M. : Genome-wide analysis reveals new roles for the activation domains of the saccharomyces cerevisiae heat shock transcription factor (Hsf1) during the transient heat shock respons. J. Biol. Chem. 281: 32909-32921, 2006.

Ferguson, S.B., Anderson, E.S., Harshaw, R.B., Thate, T., Craig, N.L., and Nelson, H.C.M. : Protein Kinase A Regulates Constitutive Expression of Small Heat-Shock Genes in an Msn2/4p-Independent and Hsf1p-Dependent Manner in Saccharomyces cerevisiae. Genetics. Fred Winston (eds.). 169: 1203-1214, 2005.

Dashnau, J.L., Conlin, L.K., Nelson, H.C., and Vanderkooi, J.M. : Water structure in vitro and within Saccharomyces cerevisiae yeast cells under conditions of heat shock. Biochimica et Biophysica Acta 1780: 41-50, 2008.

Littlefield O., Nelson HC.: A new use for the 'wing' of the 'winged' helix-turn-helix motif in the HSF-DNA cocrystal. Nature Structural Biology 6(5): 464-70, May 1999.

Wyman C., Grotkopp E., Bustamante C., Nelson HC.: Determination of heat-shock transcription factor 2 stoichiometry at looped DNA complexes using scanning force microscopy. EMBO Journal 14(1): 117-23, Jan 3 1995.

Harrison, C.J., Bohm, A.A., and Nelson, H.C.M: Crystal structure of the DNA binding domain of the heat shock transcription factor. Science 263: 224-227, 1994.

Sorger PK., Nelson HC.: Trimerization of a yeast transcriptional activator via a coiled-coil motif. Cell 59(5): 807-13, Dec 1 1989.

Nelson HC., Finch JT., Luisi BF., Klug A.: The structure of an oligo(dA).oligo(dT) tract and its biological implications. Nature 330(6145): 221-6, Nov 19-25 1987.

Nelson HC., Sauer RT.: Lambda repressor mutations that increase the affinity and specificity of operator binding. Cell 42(2): 549-58, Sep 1985.

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Last updated: 10/19/2014
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