faculty photo

Alvin J. Chin, MD

Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
Cardiology Division
Children's Hospital of Philadelphia
Main Building, Room 8NW49
34th Street and Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-738-9407
Fax: 215-590-5825
Education:
A.B. (Biochemical Sciences)
Harvard College, 1973.
M.D. (medicine)
Stanford University School of Medicine, 1977.
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Description of CVI Expertise

CVI Program Unit(s):
Cardiovascular Development / Congenital Heart Disease

CVI Research Description:
I am a pediatric cardiologist. Using the zebrafish model system, I study the molecular basis of congenital heart disease.

Ongoing Projects:
identifying a molecular pathway for left-right axis specification; elucidating the mechanisms of rostral-caudal patterning of the heart tube; characterizing the contribution of the cranial neural crest to heart tube patterning.

Selected Publications

Chin AJ, Stephens P, Goldmuntz E, Leonard MB.: Serum Alkaline Phosphatase Reflects Post-Fontan Hemodynamics in Children. Pediatr Cardiol. 30(2): 138-145. [Aug 2008 Epub ahead of print ] Feb 2009.

Chin, AJ: Single Ventricle. In Pediatrics: An Online Medical Reference (emedicine.com, now a subsidiary of WebMD.com) 2009 Notes: http://www.emedicine.com/ped/index.shtml.

Chin, AJ: Interrupted aortic arch. In Pediatrics: An Online Medical Reference 2007 Notes: http://www.emedicine.com/ped/index.shtml.

Chatterjee B, Chin AJ, Valdimarsson G, et al.: Developmental regulation and expression of the zebrafish connexin43 gene. Developmental Dynamics 233: 890-906, 2005.

Silber, JH, Cnaan, A, Clark, BJ, Paridon, SM, Chin, AJ, Rychik, J, Hogarty, AN, Cohen, MI, Barber, G, Rutkowsky, MM, Kimball, TR, Delaat, C, Steinberg, LJ, Zhao, M: Enalapril to prevent cardiac function decline in long-term survivors of pediatric cancer exposed to anthracyclines. J Clin Oncol 22: 820-829, 2004.

Ginsberg JP, Cnaan A, Zhao H, Clark BJ, Paridon SM, Chin AJ, et al.: Using health related quality of life measures to predict cardiac function in survivors exposed to anthracyclines. J Clin Oncol 22: 3149-3155, 2004.

Ryan K, Chin AJ: T-box genes and cardiac development. In birth Defects Research, Part C: Embryo Today 69: 25-37, 2003.

Kochilas, L, Potluri, V, Gitler, A, Balasubramanian, K, Chin, AJ: Cloning and characterization of zebrafish tbx1. Gene Expr Patterns 3: 645-651, 2003.

Chatterjee, B, Ki YX, Zdamowicz, M, Sonntag, JM, Chin, AJ, Kozlowski, DJ, Valdimarrson, G, Kirby, ML, Lo CW: Analysis of cx43al promoter function in the developing zebrafish embryo. Cell Adhes Commun 8: 289-292, 2001.

Fogel, MA, Rychik, J, Chin, AJ, Hubbard, A, Weinberg, PM: Evaluation and follow-up of patients with left ventricular apical to aortic conduits with 2D and 3D magnetic resonance imagine and Doppler echocardiography: A new look at an old operation. American Heart Journal 141: 630-636, 2001.

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Last updated: 08/23/2009
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