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Neil R. Malhotra, M.D.

Neil R. Malhotra, M.D.

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Assistant Professor of Neurosurgery at the Pennsylvania Hospital
Department: Neurosurgery

Contact information
Vice Chairman
Department of Neurosurgery
3rd Floor Silverstein Pavilion
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-615-5454
Fax: 215-349-5534
BA (High Distinction Scholar)
University of Virginia, 1997.
MD (Doctor of Medicine)
University of Virginia, 2002.
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Description of Research Expertise

As co-director of the translational spinal research laboratory Dr. Malhotra primary research interests focus on restorative approaches to treat disc degeneration. His novel approach has led to multiple awards and research grants. Dr. Malhotra, through his work, hopes to reduce the need for invasive surgery and offer better treatments for disc degeneration. His interests focus on tissue engineering to develop treatments to restore native tissue mechanics of the spine while delivering therapeutic agents and supporting tissue regeneration.

Description of Clinical Expertise

Dr. Malhotra is the Vice Chairman for Operations of the Department of Neurological Surgery. He oversees strategic initiatives to enhance the quality of patient care. Dr. Malhotra's work, along with that of his partners, has led to the University of Pennsylvania being the top rated neurosurgical department in the region for every year that the rankings have been completed. Further, the department is ranked amongst the top 10 in the United States.

From a clinical standpoint Dr. Malhotra provides expertise in the care of brain and spine neurological disorders. He takes particular interest in the development of advanced approaches to brain and spinal tumor resection and spinal column reconstruction as well as treatment of cervical and lumbar disc herniation. His clinical goals focus on optimizing quality of life as well as life expectancy for disorders of the nervous system. Where surgery is not indicated Dr. Malhotra leads the interdisciplinary physician group to ensure optimal care is provided to his patients.

As director of the Neurosurgery Quality Improvement Initiative Dr. Malhotra has developed a software system within the electronic medical record to enhance disease management and predict response to therapy. His system, the EpiLog project, has completed beta testing and not only is and live use at the University of Pennsylvania but is being considered for adoption at a wide range of national institutions.

In 2011 Dr. Malhotra developed an outreach program in order to enhance patient care. To support this program Dr. Malhotra sees patients in King of Prussia and Chestnut Hill, in addition to his primary site at the University of Pennsylvania.

Selected Publications

Boockvar JA, Stiefel M, Malhotra NR, Dolinskas C, Dwyer-Joyce C, LeRoux PD: Dural Cavernous Angioma of the Posterior Sagittal Sinus Surg Neurol 63(2): 178-181, Feb. 2005.

Cloyd JM, Malhotra NR, Weng L, Chen W, Mauck RL, Elliott DM: Material properties in unconfined compression of human nucleus pulposus, injectable hyaluronic acid-based hydrogels and tissue engineering scaffolds Eur Spine J 16(11): 1892-1898, Nov 2007.

Chen HI, Malhotra NR, Oddo M, Heuer GG, Levine JM, LeRoux PD: Barbiturate infusion for intractable intracranial hypertension and its effect on brain oxygenation. Neurosurgery 63(5): 880-6, Nov 2008.

Malhotra NR, Thomas P, Grady MS: Injury to the Spine. Trauma: Contemporary Principles and Therapy. Flint L, Meredith JW, Schwalb CW, Trunkey DD, Rue LW, Taheri PA (eds.). Lippincott Williams & Wilkins, Philadelphia, PA, Page: 297-304, 2008 Notes: Chapter 28.

Neil R. Malhotra, M.D.: An In-Situ Polymerizing Hydrogel to Mimic Nucleus Pulposus Ex Vivo and In Vitro. Society Scientific Paper of the Year: Pennsylvania Neurosurgical Society Meeting, Hershey, PA. July 2008 Notes: Abstract presentation.

Malhotra NR: The Best Operation for Chronic Subdural Hematoma: A Decision Analysis. Best Scientific Poster Award: Pennsylvania Neurosurgical Society Meeting, Hershey, PA. July 2008 Notes: Abstract presentation.

Malhotra NR, Grady MS: Anterior Cervical Foraminotomy Technique. Spine Surgery: Tricks of the Trade, 2nd ed. Vacaro AR (eds.). Thieme Medical Publishers, Inc. Page: 54-56, 2009 Notes: Chapter 15.

Malhotra NR, Whitfield P: Review of “The Legacy of Harvey Cushing.” Advances in Clinical Neuroscience and Rehabilitation (ACNR) 8(3), 2008.

Thomas P., Malhotra, N.R., Grady M.S.: Injury to the Spinal Cord. Trauma: Contemporary Principles and Therapy. Flint, L., Meredith, W., Schwalb, W., Taheri, P., Trunkey, D. (Ed.) (eds.). Lippincott Williams & Wilkins, 2008.

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Last updated: 10/01/2014
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