Happy Holidays from the Balice-Gordon Lab!
We study the cellular and molecular interactions among neurons, their targets and the surrounding glia that underlie synapse formation and function during neural development. We use neuromuscular synapses between motor neurons and muscle fibers in mice and zebrafish, and CNS synapses among rat and mouse hippocampal neurons in vitro, as relatively simple, accessible and easily manipulated model systems. We use imaging, genetic, cellular, molecular and electrophysiological approaches in our research projects.
The goal of our work is to understand the rules by which the neural circuits that underlie particular behaviors become synaptically connected during neural development, what governs the plasticity of these circuits, what goes wrong with these circuits in neurodevelopmental and other neurological disorders, and how we might design and implement effective therapeutic strategies.
Lab Contact Info
Rita Balice-Gordon, Ph.D.
Professor, Dept. of Neuroscience
Perelman School of Medicine at the Univ. of Pennsylvania
215 Stemmler Hall
Philadelphia, PA 19104-6074
Office: (215) 898-1037 151 Johnson Pavilion (enter through 153 JP)
Main Lab: (215) 898-3575 156 - 165JP
Rig Room: (215) 746-2719 140 Johnson Pavilion
Confocal Room: 156 Johnson Pavilion
Zebrafish Room: (215) 898-0978 201 Stemmler
Fax: (215) 573-9122
This site was last updated on December 22, 2011.