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Center for Pharmacoepidemiology Research and Training (CPeRT)

CPeRT News Items and Recent Publication

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Congratulations to PhD Student, Mei Zhou, for Best Spotlight Poster Winner at the 32nd International Conference on Pharmacoepidemiology & Therapeutic Risk Management.



  • BT Samuelson; A Cuker, MD, MS; DM Siegal; M Crowther; and DA Garcia publish "Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants (DOACs): A Systematic Review" in Chest, Epub ahead of print 13 September 2016. Read full article.

  • L Na; Q Pan; D Xie, PhD; JE Kurichi; JE Streim, MD; HR Bogner, MD, MSCE; D Saliba; and S Hennessy, PharmD, PhD publish “Activity Limitation Stages Are Associated with Hospitalization Risk among Medicare Beneficiaries” in Science Direct, Epub ahead of print 21 September 2016. Read full article.

  • V Batra; M Makvandi; AF Zuppa, MD, MSCE; N Patel; J Elias; DA Pryma; and JM Maris publish "Dexmedetomidine does not interfere with meta-iodobenzylguanidine (MIBG) uptake at clinically relevant concentrations" in Pediatric Blood & Cancer, Epub ahead of print 22 September 2016. Read full article.

  • JH Han, MD, MSCE; K Gordon; JA Womack; CL Gibert; DA Leaf; D Rimland; MC Rodriguez-Barradas; and GP Bisson, MD, MSCE publish "Comparative Effectiveness of Diabetic Oral Medications Among HIV-Infected and HIV-Uninfected Veterans" in Diabetes Care, Epub ahead of print 15 September 2016. Read full article.

  • KLH Ioannides; J Chapman; T Marukutira; O Tshume; G Anabwani; R Gross, MD, MSCE; and ED Lowenthal, MD, MSCE publish "Patterns of HIV Treatment Adherence do not Differ Between Male and Female Adolescents in Botswana" in AIDS and Behavior, Epub ahead of print 8 September 2016. Read full article.

  • BT Samuelson and A Cukerb, MD, MSCE publish "Measurement and reversal of the direct oral anticoagulants" in Blood Reviews, Epub ahead of print 2 September 2016. Read full article.

  • SE Kimmel, MD, MSCE; AB Troxel; B French, PhD; G Loewenstein; JA Doshi, PhD; TE Hecht, MD, SFHM, FACP; M Laskin, CM Brensinger; C Meussner; and K Volpp, MD, PhD publish “A randomized trial of lottery-based incentives and reminders to improve warfarin adherence: the Warfarin Incentives (WIN2) Trial” in Pharmacoepidemiology Drug Safety, Epub ahead of print 4 September 2016. Read full article.

  • M Drees; JS Gerber, MD, PhD, MSCE; DJ Morgan DJ; and GM Lee, MD publish "Research Methods in Healthcare Epidemiology and Antimicrobial Stewardship: Use of Administrative and Surveillance Databases" in Infection Control & Hospital Epidemiology, Epub ahead of print 30 August 2016. Read full article.

  • M Fabbro; JT Gutsche; TA Miano, PharmD, MSCE; JG Augoustides, MD, FASE, FAHA; and PA Patel, MD publish "Comparison of Thrombelastography-Derived Fibrinogen Values at Rewarming and Following Cardiopulmonary Bypass in Cardiac Surgery Patients" in Anesthesia & Analgesia, 2016 Sep;123(3):570-7. Read Full article.

  • ZC Chiesa Fuxench, MD; AB Troxel, ScD; JM Gelfand, MD, MSCE publish "Validity of diagnosis codes for identifying cutaneous squamous cell carcinoma in The Health Improvement Network" in the British Journal of Dermatology, Epub ahead of print 12 August 2016. Read full article.

  • Jalpa A. Doshi, PhD; Raymond Lim, MA; Pengxiang Li, PhD; Peinie P. Young; Victor F. Lawnicki; Joseph J. State; Andrea B. Troxel, ScD; and Kevin G. Volpp, MD, PhD publish "A Synchronized Prescription Refill Program Improved Medication Adherence" in Health Affairs, 35(8):1504-1512, 2016. Read full article.

  • John S. Barbieri, MD,MBA; Ole Hoffstad, MA; and David J. Margolis, MD, PhD publish "Duration of oral tetracycline-class antibiotic therapy and use of topical retinoids for the treatment of acne among general practitioners (GP): A retrospective cohort study" in the Journal of the American Academy of Dermatology, Epub ahead of print 5 August 2016. Read full article.
  • K Chiotos; N Vendetti; TE Zaoutis, MD, MSCE; J Baddley; L Ostrosky-Zeichner; P Pappas; and BT Fisher, DO, MSCE, MPH publish "Comparative effectiveness of echinocandins versus fluconazole therapy for the treatment of adult candidaemia due to Candida parapsilosis: a retrospective observational cohort study of the Mycoses Study Group (MSG-12)" in the Journal Antimicrobial Chemotherapy, Epub ahead of print 27 July 2016. Read full article.

    What is Pharmacoepidemiology?

    Pharmacoepidemiology is the study of the health effects of drugs and other medical products in populations. It is the basic science underlying the public health practice of medical product safety surveillance. Pharmacoepidemiologists apply the research methods of epidemiology (e.g., randomized trials, cohort studies, case-control studies, self-controlled designs) to the study of pharmacology (e.g., determinants of beneficial and adverse drug effects, effects of genetic variation on drug effect, dose-response relationships, duration-response relationships, drug-drug interactions, effects of non-adherence). Pharmacoepidemiologists also evaluate programmatic efforts to improve medication use.

    CPeRT Mission

    The Center for Pharmacoepidemiology Research and Training (CPeRT) was founded in 2012 (although Penn faculty member have been conducting pharmacoepidemiology research since the early 1980s) and is based in the Center for Clinical Epidemiology and Biostatistics (CCEB). Its mission is to:

    • Provide an intellectual home for pharmacoepidemiology at Penn
    • Promote the conduct of applied and methodologic pharmacoepidemiology research
    • Foster training of the next generation of pharmacoepidemiologists
    • Expand number of Penn faculty members performing pharmacoepidemiology research

    CPeRT members are leaders in the development and use of large administrative and medical record databases for studying drug effects. CPeRT is one of the academic partners of the Food and Drug Administration (FDA)-funded Mini-Sentinel Initiative. CPeRT members also edit Pharmacoepidemiology, 5th edition and Textbook of Pharmacoepidemiology.

    Training Programs

    Pilot Grant Program

    Open Faculty Positions

    View a listing of open faculty positions in Biostatistics and Epidemiology.



    Standing or Associated Penn faculty engaged in pharmacoepidemiologic research

    Associate Investigators

    Research staff who work with Penn faculty and who are engaged in pharmacoepidemiologic research

    Adjunct Investigators

    CCEB Adjunct Scholars engaged in pharmacoepidemiologic research

    For information on obtaining an Adjunct Scholar appointment within the CCEB, please contact Sue White, Manager of Faculty Affairs (; 215-573-3874).


    Trainees in Penn research training programs (including postdoctoral fellowships), instructors, and research associates, engaged in pharmacoepidemiologic research
    • Jordy Cohen, MD
    • James Crispo, PhD
    • Caitlin Elgarten, MD
    • Darcy Ellis, MPH
    • Michael George, MD
    • Erwin Calgua Guerra, MD
    • Eileen (Xu) Han, PhD
    • Xinyao Ji
    • Todd A. Miano, PharmD, MSCE
    • Young Hee Nam, PhD
    • Megan Noe, MD
    • M. Elle Saine, MA
    • Andrew Spieker
    • Sony Tuteja-Stevens, PharmD, MS
    • Adam Waxman, MD
    • Jing Zhang, MHS
    • Quingyuan Zho, PhD
    • Meijia Zhou, MHS

    For infomation on joining CPeRT, please contact Sean Hennessy, PharmD, PhD, CPeRT Director (; 215-898-9112).