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Center for Pharmacoepidemiology Research and Training (CPeRT)

CPeRT News Items and Recent Publication

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Announcements

Congratulations to PhD Student, Mei Zhou, for Best Spotlight Poster Winner at the 32nd International Conference on Pharmacoepidemiology & Therapeutic Risk Management.

 

Publications

  • E Patorno; JJ Gagne; CY Lu; K Haynes; AT Sterrett; JA Roy, PhD; X Wang, MS; and MA Raebel publish "The Role of Hemoglobin Laboratory Test Results for the Detection of Upper Gastrointestinal Bleeding Outcomes Resulting from the Use of Medications in Observational Studies" in Drug Safety, Epub ahead of print 15 November 2016. Read full article.

  • H Yun; F Xie; RN Beyl; L Chen; JD Lewis, MD, MSCE; KG Saag; and JR Curtis publish "The Risk of Hypersensitivity Associated with Biologic Use among Medicare Patients with Rheumatoid Arthritis" in Arthritis Care & Research, Epub ahead of print 3 November 2016. Read full article.

  • KJ Lum; CE Newcomb; JA Roy, PhD; DM Carbonari; ME Saine; S Cardillo, MD; H Bhullar; AM Gallagher; and V Lo Re 3rd, MD, MSCE publish "Evaluation of methods to estimate missing days' supply within pharmacy data of the Clinical Practice Research Datalink (CPRD) and The Health Improvement Network (THIN)" in the European Journal of Clinical Pharmacology, Epub ahead of print 27 October 2016. Read full article.

  • X Ji; DS Small, PhD; CE Leonard, PharmD, MSCE; and S Hennessy, PharmD, PhD publish"The Trend-in-Trend Research Design for Causal Inference" in Epidemiology, Epub ahead of print 20 October 2016. Read full article.

  • SC Denaxas; FW Asselbergs;and JH Moore, PhD, publish "The tip of the iceberg: challenges of accessing hospital electronic health record data for biological data mining" in BioData Mining, Epub ahead of print 22 September 2016. Read full article.

  • MG Amato MG; A Salazar; TT Hickman; AJ Quist; LA Volk; A Wright; D McEvoy; WL Galanter; R Koppel; B Loudin; J Adelman; JD McGreevey III; DH Smith; DW Bates; and GD Schiff publish "Computerized prescriber order entry-related patient safety reports: analysis of 2522 medication errors" in The Journal of the American Medical Informatics Association, Epub ahead of print 27 September 2016. Read full article.

  • D. A. Leiman; BP Riff; S Morgan; DC Metz, MD; GW Falk, MD, MS; B French, PhD; CA Umscheid, MD, MSCE; JD Lewis, MD, MSCE publish "Alginate therapy is effective treatment for gastroesophageal reflux disease symptoms: a systematic review and meta-analysis" in Diseases of the Esophagus, Epub ahead of print 26 September 2016. Read full article.

  • BT Samuelson; A Cuker, MD, MS; DM Siegal; M Crowther; and DA Garcia publish "Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants (DOACs): A Systematic Review" in Chest, Epub ahead of print 13 September 2016. Read full article.

  • L Na; Q Pan; D Xie, PhD; JE Kurichi; JE Streim, MD; HR Bogner, MD, MSCE; D Saliba; and S Hennessy, PharmD, PhD publish “Activity Limitation Stages Are Associated with Hospitalization Risk among Medicare Beneficiaries” in Science Direct, Epub ahead of print 21 September 2016. Read full article.

  • V Batra; M Makvandi; AF Zuppa, MD, MSCE; N Patel; J Elias; DA Pryma; and JM Maris publish "Dexmedetomidine does not interfere with meta-iodobenzylguanidine (MIBG) uptake at clinically relevant concentrations" in Pediatric Blood & Cancer, Epub ahead of print 22 September 2016. Read full article.

  • JH Han, MD, MSCE; K Gordon; JA Womack; CL Gibert; DA Leaf; D Rimland; MC Rodriguez-Barradas; and GP Bisson, MD, MSCE publish "Comparative Effectiveness of Diabetic Oral Medications Among HIV-Infected and HIV-Uninfected Veterans" in Diabetes Care, Epub ahead of print 15 September 2016. Read full article.

  • KLH Ioannides; J Chapman; T Marukutira; O Tshume; G Anabwani; R Gross, MD, MSCE; and ED Lowenthal, MD, MSCE publish "Patterns of HIV Treatment Adherence do not Differ Between Male and Female Adolescents in Botswana" in AIDS and Behavior, Epub ahead of print 8 September 2016. Read full article.


    What is Pharmacoepidemiology?

    Pharmacoepidemiology is the study of the health effects of drugs and other medical products in populations. It is the basic science underlying the public health practice of medical product safety surveillance. Pharmacoepidemiologists apply the research methods of epidemiology (e.g., randomized trials, cohort studies, case-control studies, self-controlled designs) to the study of pharmacology (e.g., determinants of beneficial and adverse drug effects, effects of genetic variation on drug effect, dose-response relationships, duration-response relationships, drug-drug interactions, effects of non-adherence). Pharmacoepidemiologists also evaluate programmatic efforts to improve medication use.

    CPeRT Mission

    The Center for Pharmacoepidemiology Research and Training (CPeRT) was founded in 2012 (although Penn faculty member have been conducting pharmacoepidemiology research since the early 1980s) and is based in the Center for Clinical Epidemiology and Biostatistics (CCEB). Its mission is to:

    • Provide an intellectual home for pharmacoepidemiology at Penn
    • Promote the conduct of applied and methodologic pharmacoepidemiology research
    • Foster training of the next generation of pharmacoepidemiologists
    • Expand number of Penn faculty members performing pharmacoepidemiology research

    CPeRT members are leaders in the development and use of large administrative and medical record databases for studying drug effects. CPeRT is one of the academic partners of the Food and Drug Administration (FDA)-funded Mini-Sentinel Initiative. CPeRT members also edit Pharmacoepidemiology, 5th edition and Textbook of Pharmacoepidemiology.

    Training Programs

    Pilot Grant Program

    Open Faculty Positions

    View a listing of open faculty positions in Biostatistics and Epidemiology.

    Leadership

    Investigators

    Standing or Associated Penn faculty engaged in pharmacoepidemiologic research

    Associate Investigators

    Research staff who work with Penn faculty and who are engaged in pharmacoepidemiologic research

    Adjunct Investigators

    CCEB Adjunct Scholars engaged in pharmacoepidemiologic research

    For information on obtaining an Adjunct Scholar appointment within the CCEB, please contact Sue White, Manager of Faculty Affairs (susanlw@mail.med.upenn.edu; 215-573-3874).

    Investigators-in-Training

    Trainees in Penn research training programs (including postdoctoral fellowships), instructors, and research associates, engaged in pharmacoepidemiologic research
    • Nicolas Bamat, MD
    • Jordy Cohen, MD
    • James Crispo, PhD
    • Caitlin Elgarten, MD
    • Darcy Ellis, MPH
    • Kelly D. Getz PhD
    • Michael George, MD
    • Erwin Calgua Guerra, MD
    • Eileen (Xu) Han, PhD
    • Xinyao Ji
    • Todd A. Miano, PharmD, MSCE
    • Young Hee Nam, PhD
    • Megan Noe, MD
    • M. Elle Saine, MA
    • Andrew Spieker
    • Sony Tuteja-Stevens, PharmD, MS
    • Adam Waxman, MD
    • Jing Zhang, MHS
    • Qingyuan Zhao, PhD
    • Meijia Zhou, MHS

    For infomation on joining CPeRT, please contact Sean Hennessy, PharmD, PhD, CPeRT Director (hennessy@upenn.edu; 215-898-9112).

    Resources