Faculty Publications 2012-2013
Marisa Bartolomei
A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection. Deng Z, Wang Z, Stong N, Plasschaert R, Moczan A, Chen HS, Hu S, Wikramasinghe P, Davuluri RV, Bartolomei MS, Riethman H, Lieberman PM. EMBO J. 2012 Nov 5;31(21):4165-78
Nonrandom X Chromosome Inactivation is Influenced by Multiple Regions on the Murine X Chromosome. Thorvaldsen JL, Krapp C, Willard HF, Bartolomei MS. Genetics. 2012 Aug 10.
Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice. de Waal E, Yamazaki Y, Ingale P, Bartolomei MS, Yanagimachi R, McCarrey JR. Hum Mol Genet. 2012 Jul 30.
Shelley Berger
A chromatin link to caste identity in the carpenter ant Camponotus floridanus.Simola DF, Ye C, Mutti NS, Dolezal K, Bonasio R, Liebig J, Reinberg D, Berger SL. Genome Res. 2013 Mar;23(3):486-96.
Low-hanging fruit: targeting Brdt in the testes. Bryant JM, Berger SL. EMBO J. 2012 Sep 7.
Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals sex-specific signatures of odor coding. Zhou X, Slone JD, Rokas A, Berger SL, Liebig J, Ray A, Reinberg D, Zwiebel LJ. PLoS Genet. 2012 Aug;8(8):e1002930.
Erfei Bi
Targeting and functional mechanisms of the cytokinesis-related F-BAR protein Hof1 during the cell cycle. Oh Y, Schreiter J, Nishihama R, Wloka C, Bi E. Mol Biol Cell. 2013 Mar 6.
Immobile myosin-II plays a scaffolding role during cytokinesis in budding yeast. Wloka C, Vallen EA, Thé L, Fang X, Oh Y, Bi E. J Cell Biol. 2013 Feb 4;200(3):271-86.
Mechanisms of cytokinesis in budding yeast. Wloka C, Bi E. Cytoskeleton (Hoboken). 2012 Jun 26.
Steve DiNardo
magu is required for germline stem cell self-renewal through BMP signaling in the Drosophila testis. Zheng Q, Wang Y, Vargas E, Dinardo SDev Biol.
2011 Sep 1;357(1):202-10
J.A. Epstein
Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells. Takeda N, Jain R, Leboeuf MR, Padmanabhan A, Wang Q, Li L, Lu MM, Millar SE, Epstein JA. Development. 2013 Mar 13.
Resolution of defective dorsal aortae patterning in Sema3E deficient mice occurs via angiogenic remodeling. Meadows SM, Ratliff LA, Singh MK, Epstein JA, Cleaver O. Dev Dyn. 2013 Feb 27.
New approaches under development: cardiovascular embryology applied to heart disease. Degenhardt K, Singh MK, Epstein JA. J Clin Invest. 2013 Jan 2;123(1):71-4.
Shannon Fisher
Skeletogenic fate of zebrafish cranial and trunk neural crest. Kague E, Gallagher M, Burke S, Parsons M, Franz-Odendaal T, Fisher S. PLoS One. 2012;7(11):e47394. doi: 10.1371/journal.pone.0047394. Epub 2012 Nov 14.
Multiple enhancers associated with ACAN suggest highly redundant transcriptional regulation in cartilage. Hu G, Codina M, Fisher S. Matrix Biol. 2012 Jul 20.
Evolution of the bone gene regulatory network. Fisher S, Franz-Odendaal T. Curr Opin Genet Dev. 2012 Aug;22(4):390-7. Epub 2012 Jun 2.
Clara Franzini-Armstrong
Kissing and nanotunneling mediate intermitochondrial communication in the heart. Huang X, Sun L, Ji S, Zhao T, Zhang W, Xu J, Zhang J, Wang Y, Wang X, Franzini-Armstrong C, Zheng M, Cheng H. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2846-51.
Mutation of sec63 in zebrafish causes defects in myelinated axons and liver pathology. Monk KR, Voas MG, Franzini-Armstrong C, Hakkinen IS, Talbot WS. Dis Model Mech. 2012 Aug 3.
Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis. Boncompagni S, Thomas M, Lopez JR, Allen PD, Yuan Q, Kranias EG, Franzini-Armstrong C, Perez CF. PLoS One. 2012;7(7):e39962. Epub 2012 Jul 2.
John Gearhart
Genome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells. Pashai N, Hao H, All A, Gupta S, Chaerkady R, De Los Angeles A, Gearhart JD, Kerr CL. PLoS One. 2012;7(6):e39088. Epub 2012 Jun 21.
Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. Addis RC, Hsu FC, Wright RL, Dichter MA, Coulter DA, Gearhart JD. PLoS One. 2011;6(12):e28719. Epub 2011 Dec 9.
Identification of RNA binding motif proteins essential for cardiovascular development. Maragh S, Miller RA, Bessling SL, McGaughey DM, Wessels MW, de Graaf B, Stone EA, Bertoli-Avella AM, Gearhart JD, Fisher S, McCallion AS. BMC Dev Biol. 2011 Oct 19;11:62.
Amin Ghabrial
Osmotic regulation of seamless tube growth. Schottenfeld-Roames J, Ghabrial AS. Nat Cell Biol. 2013 Feb;15(2):137-9.
Whacked and Rab35 polarize dynein-motor-complex-dependent seamless tube growth. Schottenfeld-Roames J, Ghabrial AS. Nat Cell Biol. 2012 Mar 11. doi: 10.1038/ncb2454. [Epub ahead of print]
A Sweet Spot in the FGFR Signal Transduction Pathway. Ghabrial AS. Sci Signal. 2012 Jan 17;5(207):pe1.
Michael Granato
Temporal requirement for SMN in motoneuron development. Hao LT, Duy PQ, Jontes JD, Wolman M, Granato M, Beattie CE. Hum Mol Genet. 2013 Mar 3.
A novel role for Lh3 dependent ECM modifications during neural crest cell migration in zebrafish. Banerjee S, Isaacman-Beck J, Schneider VA, Granato M. PLoS One. 2013;8(1):e54609. doi: 10.1371/journal.pone.0054609. Epub 2013 Jan 18.
Plexin A3 and turnout regulate motor axonal branch morphogenesis in zebrafish. Sainath R, Granato M. PLoS One. 2013;8(1):e54071. doi: 10.1371/journal.pone.0054071. Epub 2013 Jan 21.
The tumor suppressor gene retinoblastoma-1 is required for retinotectal development and visual function in zebrafish. Gyda M, Wolman M, Lorent K, Granato M. PLoS Genet. 2012;8(11):e1003106. doi: 10.1371/journal.pgen.1003106. Epub 2012 Nov 29.
Dan Kessler
Transcriptional integration of Wnt and Nodal pathways in establishment of the Spemann organizer. Reid CD, Zhang Y, Sheets MD, Kessler DS. Dev Biol. 2012 May 22
Mary Mullins
Dynamic Assembly of Brambleberry Mediates Nuclear Envelope Fusion during Early Development. Abrams EW, Zhang H, Marlow FL, Kapp L, Lu S, Mullins MC. Cell. 2012 Aug 3;150(3):521-32.
Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish. Eauclaire SF, Cui S, Ma L, Matous J, Marlow FL, Gupta T, Burgess HA, Abrams EW, Kapp LD, Granato M, Mullins MC, Matthews RP. Dev Biol. 2012 May 15;365(2):434-44. Epub 2012 Mar 16.
An intermediate level of BMP signaling directly specifies cranial neural crest progenitor cells in zebrafish. Schumacher JA, Hashiguchi M, Nguyen VH, Mullins MC. PLoS One. 2011;6(11):e27403.
Neal Rubinstein
Identification of the neuromuscular junction (NMJ) transcriptome of extraocular muscle (EOM) by laser capture microdissection (LCM). Ketterer C, Zeiger U, Budak MT, Rubinstein NA, Khurana TS. Invest Ophthalmol Vis Sci. 2010 Apr 14.
Patrick Seale
MicroRNA-133 Controls Brown Adipose Determination in Skeletal Muscle Satellite Cells by Targeting Prdm16. Yin H, Pasut A, Soleimani VD, Bentzinger CF, Antoun G, Thorn S, Seale P, Fernando P, van Ijcken W, Grosveld F, Dekemp RA, Boushel R, Harper ME, Rudnicki MA. Cell Metab. 2013 Feb 5;17(2):210-24.
Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity. Derecka M, Gornicka A, Koralov SB, Szczepanek K, Morgan M, Raje V, Sisler J, Zhang Q, Otero D, Cichy J, Rajewsky K, Shimoda K, Poli V, Strobl B, Pellegrini S, Harris TE, Seale P, Russell AP, McAinch AJ, O'Brien PE, Keller SR, Croniger CM, Kordula T, Larner AC. Cell Metab. 2012 Dec 5;16(6):814-24.
An Evi1-C/EBPβ complex controls Pparγ2 expression to initiate white fat cell differentiation. Ishibashi J, Firtina Z, Rajakumari S, Wood KH, Conroe HM, Steger DJ, Seale P. Mol Cell Biol. 2012 Apr 2.
Celeste Simon
Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism. McClain DA, Abuelgasim KA, Nouraie M, Salomon-Andonie J, Niu X, Miasnikova G, Polyakova LA, Sergueeva A, Okhotin DJ, Cherqaoui R, Okhotin D, Cox JE, Swierczek S, Song J, Simon MC, Huang J, Simcox JA, Yoon D, Prchal JT, Gordeuk VR. J Mol Med (Berl). 2013 Jan;91(1):59-67.
Hypoxia-induced angiogenesis: good and evil. Krock BL, Skuli N, Simon MC. Genes Cancer. 2011 Dec;2(12):1117-33.
Untuning the tumor metabolic machine: HIF-α: pro- and antitumorigenic? Young RM, Simon MC. Nat Med. 2012 Jul 6;18(7):1024-5. doi: 10.1038/nm.2865.
Nancy Speck
Attenuation of AML1-ETO cellular dysregulation correlates with increased leukemogenic potential. Dekelver RC, Yan M, Ahn EY, Shia WJ, Speck NA, Zhang DE. Blood. 2013 Feb 20.
Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells. Chou ST, Byrska-Bishop M, Tober JM, Yao Y, Vandorn D, Opalinska JB, Mills JA, Choi JK, Speck NA, Gadue P, Hardison RC, Nemiroff RL, French DL, Weiss MJ. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17573-8. doi: 10.1073/pnas.1211175109. Epub 2012 Oct 8.
Tyrosyl phosphorylation toggles a Runx1 switch. Neel BG, Speck NA. Genes Dev. 2012 Jul 15;26(14):1520-6.
Phong Tran
Common mechanisms regulating cell cortex properties during cell division and cell migration. Roubinet C, Tran PT, Piel M. Cytoskeleton (Hoboken). 2012 Nov;69(11):957-72. doi: 10.1002/cm.21086. Epub 2012 Nov 1.
Motor proteins: kinesin can replace Myosin. Scheffler K, Tran PT. Curr Biol. 2012 Jan 24;22(2):R52-4.
John Weisel
Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion. Wang Y, Zhao L, Suzuki A, Lian L, Min SH, Wang Z, Litvinov RI, Stalker TJ, Yago T, Klopocki AG, Schmidtke DW, Yin H, Choi JK, McEver RP, Weisel JW, Hartwig JH, Abrams CS. Blood. 2013 Jan 31.
Mechanisms of fibrin polymerization and clinical implications. Weisel JW, Litvinov RI. Blood. 2013 Mar 7;121(10):1712-9.
Visualization of the dynamics of fibrin clot growth one molecule at a time by total internal reflection fluorescence microscopy. Hategan A, Gersh KC, Safer D, Weisel JW. Blood. 2012 Dec 11.
Ken Zaret
Bookmarking by specific and nonspecific binding of FoxA1 pioneer factor to mitotic chromosomes. Caravaca JM, Donahue G, Becker JS, He X, Vinson C, Zaret KS. Genes Dev. 2013 Feb 1;27(3):251-60.
Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Soufi A, Donahue G, Zaret KS. Cell. 2012 Nov 21;151(5):994-1004. doi: 10.1016/j.cell.2012.09.045. Epub 2012 Nov 15.
Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice. Serup P, Gustavsen C, Klein T, Potter LA, Lin R, Mullapudi N, Wandzioch E, Hines A, Davis A, Bruun C, Engberg N, Petersen DR, Peterslund JM, Macdonald RJ, Grapin-Botton A, Magnuson MA, Zaret KS. Dis Model Mech. 2012 Aug 10.
