Faculty Publications 2011-2012
Marisa Bartolomei
Nonrandom X Chromosome Inactivation is Influenced by Multiple Regions on the Murine X Chromosome. Thorvaldsen JL, Krapp C, Willard HF, Bartolomei MS. Genetics. 2012 Aug 10.
Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice. de Waal E, Yamazaki Y, Ingale P, Bartolomei MS, Yanagimachi R, McCarrey JR. Hum Mol Genet. 2012 Jul 30.
Imprinted genes … and the number is? Kelsey G, Bartolomei MS. PLoS Genet. 2012 Mar;8(3):e1002601. Epub 2012 Mar 29.
Shelley Berger
Low-hanging fruit: targeting Brdt in the testes. Bryant JM, Berger SL. EMBO J. 2012 Sep 7. doi: 10.1038/emboj.2012.259.
Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals sex-specific signatures of odor coding. Zhou X, Slone JD, Rokas A, Berger SL, Liebig J, Ray A, Reinberg D, Zwiebel LJ. PLoS Genet. 2012 Aug;8(8):e1002930.
Genome-wide and Caste-Specific DNA Methylomes of the Ants Camponotus floridanus and Harpegnathos saltator. Bonasio R, Li Q, Lian J, Mutti NS, Jin L, Zhao H, Zhang P, Wen P, Xiang H, Ding Y, Jin Z, Shen SS, Wang Z, Wang W, Wang J, Berger SL, Liebig J, Zhang G, Reinberg D. Curr Biol. 2012 Aug 7.
Erfei Bi
Mechanisms of cytokinesis in budding yeast. Wloka C, Bi E. Cytoskeleton (Hoboken). 2012 Jun 26.
Cell polarization and cytokinesis in budding yeast. Bi E, Park HO. Genetics. 2012 Jun.
Mitotic exit kinase Dbf2 directly phosphorylates chitin synthase Chs2 to regulate cytokinesis in budding yeast. Oh Y, Chang KJ, Orlean P, Wloka C, Deshaies R, Bi E. Mol Biol Cell. 2012 May 9.
Steve DiNardo
magu is required for germline stem cell self-renewal through BMP signaling in the Drosophila testis. Zheng Q, Wang Y, Vargas E, Dinardo SDev Biol.
2011 Sep 1;357(1):202-10
J.A. Epstein
Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos. Yang Y, García-Verdugo JM, Soriano-Navarro M, Srinivasan RS, Scallan JP, Singh MK, Epstein JA, Oliver G. Blood. 2012 Aug 2.
Myocardial notch signaling reprograms cardiomyocytes to a conduction-like phenotype. Rentschler S, Yen AH, Lu J, Petrenko NB, Lu MM, Manderfield LJ, Patel VV, Fishman GI, Epstein JA. Circulation. 2012 Aug 28.
Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development. Shin J, Padmanabhan A, de Groh ED, Lee JS, Haidar S, Dahlberg S, Guo F, He S, Wolman MA, Granato M, Lawson ND, Wolfe SA, Kim SH, Solnica-Krezel L, Kanki JP, Ligon KL, Epstein JA, Look AT. Dis Model Mech. 2012 Aug 3.
Shannon Fisher
Multiple enhancers associated with ACAN suggest highly redundant transcriptional regulation in cartilage. Hu G, Codina M, Fisher S. Matrix Biol. 2012 Jul 20.
Evolution of the bone gene regulatory network. Fisher S, Franz-Odendaal T. Curr Opin Genet Dev. 2012 Aug;22(4):390-7. Epub 2012 Jun 2.
Identification of RNA binding motif proteins essential for cardiovascular development. Maragh S, Miller RA, Bessling SL, McGaughey DM, Wessels MW, de Graaf B, Stone EA, Bertoli-Avella AM, Gearhart JD, Fisher S, McCallion AS. BMC Dev Biol. 2011 Oct 19;11:62.
Clara Franzini-Armstrong
Mutation of sec63 in zebrafish causes defects in myelinated axons and liver pathology. Monk KR, Voas MG, Franzini-Armstrong C, Hakkinen IS, Talbot WS. Dis Model Mech. 2012 Aug 3.
Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis. Boncompagni S, Thomas M, Lopez JR, Allen PD, Yuan Q, Kranias EG, Franzini-Armstrong C, Perez CF. PLoS One. 2012;7(7):e39962. Epub 2012 Jul 2.
Structural changes in isometrically contracting insect flight muscle trapped following a mechanical perturbation. Wu S, Liu J, Reedy MC, Perz-Edwards RJ, Tregear RT, Winkler H, Franzini-Armstrong C, Sasaki H, Lucaveche C, Goldman YE, Reedy MK, Taylor KA. PLoS One. 2012;7(6):e39422. Epub 2012 Jun 25.
John Gearhart
Genome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells. Pashai N, Hao H, All A, Gupta S, Chaerkady R, De Los Angeles A, Gearhart JD, Kerr CL. PLoS One. 2012;7(6):e39088. Epub 2012 Jun 21.
Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. Addis RC, Hsu FC, Wright RL, Dichter MA, Coulter DA, Gearhart JD. PLoS One. 2011;6(12):e28719. Epub 2011 Dec 9.
Identification of RNA binding motif proteins essential for cardiovascular development. Maragh S, Miller RA, Bessling SL, McGaughey DM, Wessels MW, de Graaf B, Stone EA, Bertoli-Avella AM, Gearhart JD, Fisher S, McCallion AS. BMC Dev Biol. 2011 Oct 19;11:62.
Amin Ghabrial
Whacked and Rab35 polarize dynein-motor-complex-dependent seamless tube growth. Schottenfeld-Roames J, Ghabrial AS. Nat Cell Biol. 2012 Mar 11. doi: 10.1038/ncb2454. [Epub ahead of print]
A Sweet Spot in the FGFR Signal Transduction Pathway. Ghabrial AS. Sci Signal. 2012 Jan 17;5(207):pe1.
Michael Granato
Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development. Shin J, Padmanabhan A, de Groh ED, Lee JS, Haidar S, Dahlberg S, Guo F, He S, Wolman MA, Granato M, Lawson ND, Wolfe SA, Kim SH, Solnica-Krezel L, Kanki JP, Ligon KL, Epstein JA, Look AT. Dis Model Mech. 2012 Aug 3.
Survival motor neuron affects plastin 3 protein levels leading to motor defects. Hao le T, Wolman M, Granato M, Beattie CE. J Neurosci. 2012 Apr 11;32(15):5074-84.
Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish. Eauclaire SF, Cui S, Ma L, Matous J, Marlow FL, Gupta T, Burgess HA, Abrams EW, Kapp LD, Granato M, Mullins MC, Matthews RP. Dev Biol. 2012 May 15;365(2):434-44. Epub 2012 Mar 16.
Dan Kessler
Transcriptional integration of Wnt and Nodal pathways in establishment of the Spemann organizer. Reid CD, Zhang Y, Sheets MD, Kessler DS. Dev Biol. 2012 May 22
Mary Mullins
Dynamic Assembly of Brambleberry Mediates Nuclear Envelope Fusion during Early Development. Abrams EW, Zhang H, Marlow FL, Kapp L, Lu S, Mullins MC. Cell. 2012 Aug 3;150(3):521-32.
Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish. Eauclaire SF, Cui S, Ma L, Matous J, Marlow FL, Gupta T, Burgess HA, Abrams EW, Kapp LD, Granato M, Mullins MC, Matthews RP. Dev Biol. 2012 May 15;365(2):434-44. Epub 2012 Mar 16.
An intermediate level of BMP signaling directly specifies cranial neural crest progenitor cells in zebrafish. Schumacher JA, Hashiguchi M, Nguyen VH, Mullins MC. PLoS One. 2011;6(11):e27403.
Neal Rubinstein
Identification of the neuromuscular junction (NMJ) transcriptome of extraocular muscle (EOM) by laser capture microdissection (LCM). Ketterer C, Zeiger U, Budak MT, Rubinstein NA, Khurana TS. Invest Ophthalmol Vis Sci. 2010 Apr 14.
Patrick Seale
An Evi1-C/EBPβ complex controls Pparγ2 expression to initiate white fat cell differentiation. Ishibashi J, Firtina Z, Rajakumari S, Wood KH, Conroe HM, Steger DJ, Seale P. Mol Cell Biol. 2012 Apr 2.
Celeste Simon
Hypoxia-induced angiogenesis: good and evil. Krock BL, Skuli N, Simon MC. Genes Cancer. 2011 Dec;2(12):1117-33.
Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis. Qi Y, Tian X, Liu J, Han Y, Graham AM, Simon MC, Penninger JM, Carmeliet P, Li S. J Cell Biol. 2012 Jul 9;198(1):103-14.
Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia-inducible factor 1α Kim YJ, Lee HJ, Kim TM, Eisinger-Mathason TS, Zhang AY, Schmidt B, Karl DL, Nakazawa MS, Park PJ, Simon MC, Yoon SS. Int J Cancer. 2012 Jun 9.
Nancy Speck
Tyrosyl phosphorylation toggles a Runx1 switch. Neel BG, Speck NA. Genes Dev. 2012 Jul 15;26(14):1520-6.
Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis. Guo H, Ma O, Speck NA, Friedman AD. Blood. 2012 May 10;119(19):4408-18.
Runx1 dose-dependently regulates endochondral ossification during skeletal development and fracture healing. Soung DY, Talebian L, Matheny CJ, Guzzo R, Speck ME, Lieberman JR, Speck NA, Drissi H. J Bone Miner Res. 2012 Mar 19.
Phong Tran
Motor proteins: kinesin can replace Myosin. Scheffler K, Tran PT. Curr Biol. 2012 Jan 24;22(2):R52-4.
John Weisel
Mechanical Transition from α-Helical Coiled-Coils to β-Sheets in Fibrin(ogen). Zhmurov A, Kononova O, Litvinov RI, Dima RI, Barsegov V, Weisel JW. J Am Chem Soc. 2012 Sep 6.
Resolving two-dimensional kinetics of the integrin αIIbβ3-fibrinogen interactions using Binding-Unbinding Correlation Spectroscopy. Litvinov RI, Mekler A, Shuman H, Bennett JS, Barsegov V, Weisel JW. J Biol Chem. 2012 Aug 14.
Diminished adhesion and activation of platelets and neutrophils with CD47 functionalized blood contacting surfaces. Finley MJ, Rauova L, Alferiev IS, Weisel JW, Levy RJ, Stachelek SJ. Biomaterials. 2012 Aug;33(24):5803-11.
Ken Zaret
Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice. Serup P, Gustavsen C, Klein T, Potter LA, Lin R, Mullapudi N, Wandzioch E, Hines A, Davis A, Bruun C, Engberg N, Petersen DR, Peterslund JM, Macdonald RJ, Grapin-Botton A, Magnuson MA, Zaret KS. Dis Model Mech. 2012 Aug 10.
Chromatin "pre-pattern" and epigenetic modulation in the cell fate choice of liver over pancreas in the endoderm. Xu CR, Zaret KS. Nucleus. 2012 Mar 1;3(2):150-4.
The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and β-cell differentiation. Metzger DE, Gasperowicz M, Otto F, Cross JC, Gradwohl G, Zaret KS. Development. 2012 Apr;139(8):1447-56.
