UPenn Cell & Developmental Biology

Publications

The following publications contain image data acquired on CDB Microscopy Core instruments

Richards Building LSM 510 NLO/META

1. Waxman EA, Giasson BI. 2010. A novel, high-efficiency cellular model of fibrillar alpha-synuclein inclusions and the examination of mutations that inhibit amyloid formation. http://www.ncbi.nlm.nih.gov/pubmed/20132485
2. Liu Y, Cocka L, Okumura A, Zhong Y, Sunyer JO, Harty RN. 2010. Conserved motifs within Ebola and Marburg virus VP40 proteins are important for stability, localization, and subsequent budding of virus-like particles. http://www.ncbi.nlm.nih.gov/pubmed/20032189
3. Lu HD, Charati MB, Kim IL, Burdick JA. 2012. Injectable shear-thinning hydrogels engineered with a self-assembling dock-and-lock mechanism. http://www.ncbi.nlm.nih.gov/pubmed/22177842
4. Boudou T, Legant WR, Mu A, Borochin MA, Thavandiran N, Radisic M, Zandstra PW, Epstein JA, Margulies KB, Chen CS. 2012. A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. http://www.ncbi.nlm.nih.gov/pubmed/22092279

BRB LSM 510 (retired)

1. Davuluri G, Seiler C, Abrams J, Soriano AJ, Pack M. 2010. Differential effects of thin and thick filament disruption on zebrafish smooth muscle regulatory proteins. http://www.ncbi.nlm.nih.gov/pubmed/20591105
2. Khetan S and Burdick JA. 2010. Patterning network structure to spatially control cellular remodeling and stem cell fate within 3-dimensional hydrogels. http://www.ncbi.nlm.nih.gov/pubmed/20674004
3. Seiler C, Abrams J, Pack M. 2010. Characterization of zebrafish intestinal smooth muscle development using a novel sm22a-b promoter. http://www.ncbi.nlm.nih.gov/pubmed/20882680
4. Pacheco-Pinedo EC, Durham AC, Stewart KM, Goss AM, Lu MM, Demayo FJ, Morrisey EE. 2011. Wnt/beta-catenin signalling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium. http://www.ncbi.nlm.nih.gov/pubmed/21490395

BRB LSM 710

1. Wu S, Koizumi K, MacRae-Crerar A, Gallagher KL. 2011. Assessing the utility of photoswitchable fluorescent proteins for tracking intracellular protein movement in the Arabidopsis root. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223184/
2. Cullen DK, Tang-Schomer MD, Struznya LA, Patel AR, JohnsonVE, Wolf JA, Smith DH. 2011. Microtissue engineered constructs with living axons for targeted nervous system reconstruction. http://www.ncbi.nlm.nih.gov/pubmed/22702955
3. Miller JS, Stevens, KR, Yang MT, Baker BM, Nguyen DT, Cohen DM, Toro E, Chen AA, Galie PA, Yu X, Chaturvedi R, Bhatia SN, Chen CS. 2012. Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues. http://www.ncbi.nlm.nih.gov/pubmed/22751181
4. Abrams EW, Zhang H, Marlow FL, Kapp L, Lu S, Mullins MC. 2012. Dynamic assembly of brambleberry mediates nuclear envelope fusion during early development. http://www.ncbi.nlm.nih.gov/pubmed/22863006

Deltavision Deconvolution

1. Wood CS, Schmitz KR, Bessman NJ, Setty TG, Ferguson KM, Burd CG. 2009. PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking. http://www.ncbi.nlm.nih.gov/pubmed/20026658
2. Shin JW, Swift J, Spinler KR, Discher DE. 2011. Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes. http://www.ncbi.nlm.nih.gov/pubmed/21709232

Spinning Disk Confocal

1. Simone RP, DiNardo S. 2010. Actomyosin contractility and Discs large contribute to junctional conversion in guiding cell alignment within the Drosophila embryonic epithelium. http://www.ncbi.nlm.nih.gov/pubmed/20332153
2. Legant WR, Miller JS, Blakely BL, Cohen DM, Genin GM, Chen CS. 2010. Measurement of mechanical tractions exerted by cells in three-dimensional matrices. http://www.ncbi.nlm.nih.gov/pubmed/21076420
3. Meshki J, Douglas SD, Hu M, Leeman SE, and Tuluc F. 2011. Substance P induces rapid and transient membrane blebbing in U373MG cells in a p21-activated kinase-dependent manner. PLoS ONE 6(9):e25332.
4. Bowen JR, Hwang D, Bai X, Roy D, Spiliotis ET. 2011. Septin GTPases spatially guide microtublue organization and plus end dynamics in polarizing epithelia. http://www.ncbi.nlm.nih.gov/pubmed/21788367
5. Rosenberg AF, Wolman MA, Franzini-Armstrong C, Granato M. 2012. In vivo nerve-macrophage interactions following peripheral nerve injury. http://www.ncbi.nlm.nih.gov/pubmed/22423110
6. Oh Y, Chang KJ, Orlean P, Wloka C, Deshaies R, Bi E. 2012. Mitotic exit kinase DBf2 directly phosphorylates chitin synthase Chs2 to regulate cytokinesis in budding yeast. http://www.ncbi.nlm.nih.gov/pubmed/22573892

Leica Confocal

1. Chen MJ, Li Y, De Obaldia ME, Yang Q, Yzaguirre AD, Yamada-Inagawa T, Vink CS, Bhandoola A, Dzierzak E, Speck NA. 2011. Erythroid/Myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells. http://www.ncbi.nlm.nih.gov/pubmed/22136929
2. Liu F, Levin MD, Petrenko NB, Lu MM, Wang T, Yuan LJ, Stout AL, Epstein JA, Patel VV. 2008. Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin. http://www.ncbi.nlm.nih.gov/pubmed/18926829