Perelman School of Medicine at the University of Pennsylvania

Chen Laboratory

Publications

2016

Pisapia JM, Kayak NR, Salinas RD, Macyzsyn L, Lee JYK, Lucas TH, Malhotra NR, Chen HI, Schuster JM: Navigated odontoid screw placement using the O-arm: technical note and case series. Journal of Neurosurgery: Spine (in press).

Richardson AG, Attiah MA, Berman JI, Chen HI, Liu X, Zhang M, Van der Spiegel J, Lucas TH: The effects of acute cortical somatosensory deafferentation on grip force control.  Cortex  74:1-8, 2016.

Chen HI, Jgamadze D, Serruya MD, Cullen DK, Wolf JA, Smith DH: Neural substrate expansion for the restoration of brain function. Frontiers in System Neuroscience 10(1), 2016.

 

2015

Struzyna L, Wolf JA, Mietus C, Adewole DO, Chen HI, Smith DH, Cullen DK: Rebuilding brain circuitry with living micro-tissue engineered neural networks.  Tissue Engineering Part A 21(21-22):2744-2756, 2015.

Chen HI, Bohman L, Emery L, Martinez-Lage M, Richardson AG, Davis KA, Pollard JR, Litt B, Gausas RE, Lucas TL: Lateral transorbital endoscopic access to the hippocampus, amygdala, and entorhinal cortex: Initial clinical experience.  ORL; Journal of Oto-rhino-laryngology and its Related Specialties 77(6):321-332, 2015.

Struzyna LA, Harris J, Katiyar K, Chen HI, Cullen DK: Restoring nervous system structure and function using tissue engineered living scaffolds.  Neural Regeneration Research 10(5):115-28, 2015.

 

2014

Lang SS, Chen HI, Koch MJ, Kurash L, McGill-Armento KR, Palella JM, Stein SC, Malhotra NR: Development of an outpatient protocol for lumbar discectomy: Our institutional experience.  World Neurosurgery 82(5):897-901, 2014.

Chen HI, Bohman L, Loevner L, Lucas TH: Transorbital endoscopic amygdalo-hippocampectomy: a feasibility investigation.  Journal of Neurosurgery 120(6):1428-1436, 2014.  [Cover article]

Chen HI, Attiah M, Baltuch G, Smith DH, Hamilton RH, Lucas TH: Harnessing plasticity for the treatment of neurosurgical disorders.  World Neurosurgery 82(5):648-659, 2014.

 

2013

Chen HI, Lang SS, Coyne TM, Malhotra NR, Schuster JM: Intramedullary spinal sarcoidosis masquerading as cervical stenosis.  World Neurosurgery 80(6):e375-380, 2013.

 

2012

Lang SS, Chen HI, Lee JYK.  Endoscopic microvascular decompression: a step-wise operative technique.  ORL; Journal of Oto-rhino-laryngology and its Related Specialties 74:293-298,2012.

 

2011

Chen HI, Stiefel MF, Oddo M, Milby AH, Maloney-Wilensky E, Frangos S, Levine JM, Kofke WA, LeRoux PD: Detection of cerebral compromise with multimodality monitoring in patients with subarachnoid hemorrhage.  Neurosurgery 69:53-63, 2011.

 

2010

Lee JYK, Chen HI, Urban C, Hojat A, Church E, Farrar JT: Development and psychometric testing of the Brief Pain Inventory-Facial for patients with facial pain.  Journal of Neurosurgery 113(3):516-523, 2010.

Oddo M, Nduom E, Frangos S, Mackenzie L, Chen HI, Maloney-Wilensky E, Kofke WA, Levine JM, LeRoux PD: Acute lung injury is an independent risk factor for brain hypoxia after severe traumatic brain injury.  Neurosurgery 67(2):338-344, 2010.

Magge SN, Chen HI, Cen L, Chen Z, Elliott JP, Winn HR, LeRoux PD: Association of younger age with an increased risk of angiographic and symptomatic vasospasm after subarachnoid hemorrhage.  Journal of Neurosurgery 112(6):1208-1215, 2010.

Evans SM, Jenkins KT, Chen HI, Jenkins WT, Judy KD, Hwang WT, Lustig RA, Magarelli DR, Judkins A, Grady MS, Hahn SM, Koch CJ: The relationship among hypoxia, proliferation, and outcome in patients with de novo glioblastoma: A pilot study.  Translational Oncology 3(3):160-169, 2010.

Chen HI, Lee JYK: The measurement of pain in trigeminal neuralgia patients.  Clinical Neurosurgery 57:129-133, 2010.

 

2009

Magge SN, Malik S, Royo NC, Chen HI, Yu L, Snyder EY, O‚ÄôRourke DM, Watson DJ: Role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in migration of neural progenitor cells towards glial tumors.  Journal of Neuroscience Research 87(7):1547-55, 2009.

Oddo M, Frangos S, Milby A, Chen HI, Maloney-Wilensky E, MacMurtrie E, Stiefel MF, Kofke WA, LeRoux PD, Levine JM: Induced normothermia attenuates cerebral metabolic distress in patients with aneurysmal subarachnoid hemorrhage and refractory fever.  Stroke 40(5):1913-6, 2009.

Oddo M, Milby A, Chen HI, Frangos S, MacMurtrie E, Maloney-Wilensky E, Stiefel MF, Kofke WA, Levine JM, LeRoux PD: Hemoglobin concentration and cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage.  Stroke 40(4):1275-81, 2009.

 

2008

Chen HI, Malhotra NR, Oddo M, Heuer GG, Levine JM, LeRoux PD: Barbiturate infusion for intractable intracranial hypertension and its effects on brain oxygenation.  Neurosurgery 63(5):880-806, 2008.

Magge SN, Chen HI, Stiefel MF, Ernst L, Cahill AM, Hurst R, Storm PB: Multiple ruptured cerebral aneurysms in a child with Takayasu Arteritis.  Journal of Neurosurgery: Pediatrics 1(1):83-8, 2008.

 

2007

Dahl J, Chen HI, George M, Benjamin TL: Polyoma small T antigen controls viral chromatin modifications through effects on kinetics of virus growth and cell cycle progression.  Journal of Virology:81(18):10064-10071, 2007.

Royo NC, LeBold D, Magge SN, Chen HI, Hauspurg A, Cohen AS, Watson DJ: Neurotrophin-mediated neuroprotection of hippocampal neurons following traumatic brain injury is not associated with acute recovery of hippocampal function.  Neuroscience 148(2):359-370, 2007.

Magge SN, Chen HI, Heuer G, Carracsco LR, Storm PB: Dislocation of the mandible into the middle cranial fossa.  Case report.  Journal of Neurosurgery: Pediatrics 107(1):75-78, 2007.

Chen HI, Heuer GG, Zaghloul K, Simon SL, Weigele JB, Grady MS: Lumbar vertebral hemangioma presenting with the acute onset of neurological symptoms.  Case report.  Journal of Neurosurgery: Spine 7(1):80-85, 2007.

Chen HI, Bakshi A, Royo NC, Magge SN, Watson DJ: Neural stem cells as biological minipumps: A faster route to cell therapy for the CNS?  Current Stem Cell Research and Therapy 2(1):13-22, 2007.

 

2006

Chen HI, Burnett MG, Huse JT, Lustig RA, Bagley LJ, Zager EL: Recurrent late cerebral necrosis with aggressive characteristics after radiosurgical treatment of an arteriovenous malformation.  Journal of Neurosurgery 105(3):455-460, 2006.

Magge SN, Chen HI, Zager EL: Dystrophic calcification and infraclavicular brachial plexopathy: Case report.  Neurosurgery 58(6):E216, 2006.