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Building Bridges to
   The Future of Cardiovascular Medicine

The Penn Cardiovascular Institute (CVI) was established in 2005 to promote transformational discoveries in cardiovascular biology and medicine. The Penn CVI bridges the expertise of scientists and clinicians across the University of Pennsylvania campus and Health System by using multi-disciplinary disease-focused research programs. The Penn CVI creates a culture where patient care, research and education are seemlessly integrated.

IN THE NEWS »

Adding Darapladib to Statins to Treat Coronary Heart Disease:
New treatment may help prevent heart attack and stroke

Reducing Racial and Ethnic Health Disparities:
Penn Receives National Grant Award for Demonstrated Interventions

A Chilling Tool Fights Cardiac Arrest:
Phila. Inquirer cites Penn's Dr. Benjamin Abella and Dr. Lance Becker

Heart Risk in ADHD Drugs? New Call for Child Cardiac Testing:
CHOP's Dr. Victoria Vetter heads American Heart Association statement writing committee

Severe Heart Failure: Keys to Survival
ReachMD Satellite Radio features Penn's Dr. Mariell Jessup

Using Stem Cells to Fix the Heart:
Miami Herald quotes Penn Researcher Dr. Ed Morrisey

Data Mining Prescribed to Ensure Drug Safety:
Penn Teams with Health Insurer on New Drug-Safety Monitoring System

Advances in Gene Therapy:
Innovative Materials Allow Better Control and Delivery via Stents

Penn Researchers Discover 'Modus Operandi' of Heart Muscle Protein:
Implications for cardiac development and health

Expert Centers for Adult Congenital Heart Disease:
ReachMD Satellite Radio features Penn's Dr. Gary Webb

Can Home AEDs Improve Survival?
Penn's Dr. Callans writes New England Journal of Medicine editorial on results of the Home Automated External Defibrillator (HAT) trial

Penn Experts Present Findings in New Drug Therapy and Gender Disparities at ACC Scientific Sessions

Early Warning System for Drugs: Firms Aim to Detect Heart Risks – SF Chronicle cites Penn's Dr. Garrett FitzGerald

Penn CVI Member Dr. Judd Hollander Contributes to AHA Statement: Doctors should check for cocaine use in younger patients with chest pain

Translating Molecular Discoveries into New Therapies for Atherosclerosis: Nature features article co-authored by Dr. Daniel Rader

Can You Diagnose and Treat Early Heart Failure?
ReachMD Satellite Radio Features Dr. Mariell Jessup

New Mitral Valve Repair Clinical Trial:
Penn's Dr. W. Clark Hargrove III is Lead Primary Investigator

What That Cholesterol Trial Showed, and What It Didn't – NY Times cites Penn's Dr. Daniel Rader

Common Congenital Heart Defect PDA:
Penn Researchers Identify Gene that Offers New Insights

Update: Researchers Use Magnetism to Target Cells to Animal Arteries

New Genetic Cause of Heart Attack and Vascular Disease:
Penn CVI Members Collaborate with deCode Genetics

Mapping Stem Cell Research:
WHYY Panel features Penn CVI Scientific Director

Penn Researcher Receives $3 Million to Study Molecular Cardiac Surgery

CT Scans in the Emergency Room May Save Time, Money

Penn Researcher Suggests Women Fare Worse with Some Heart Devices

PBS series "The Mysterious Human Heart" features Penn's Dr. Jessup and Dr. Rader

CVI Members Speak at Inaugural Clinical Cardiovascular Genomics Meeting

Penn Researchers Discover Novel Pathway for Increasing Good Cholesterol

Cardiac Stem Cells:
Key Pathway Linked to Heart Development and Regeneration of Damaged Heart Tissue

ICD Devices Offer Heart Patients Excellent Quality of Life > Podcast

Penn Cardiac Surgeons Implant First Temporary Total Artificial Heart in the Northeast U.S.

RECENT PUBLICATIONS »

The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-blind, placebo-controlled study

Long-Term Clinical Efficacy and Risk of Catheter Ablation for Atrial Fibrillation in the Elderly

Cardiac retransplantation is an efficacious therapy for primary cardiac allograft failure

Reduced effects of BAY K 8644 on L-type Ca2+ current in failing human cardiac myocytes are related to abnormal adrenergic regulation

A House with Many Rooms: How the Heart Got its Chambers with Foxn4

Antigenic stimulation in the simian model of HIV infection yields dilated cardiomyopathy through effects of TNFalpha

Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal

Atrial Fibrillation Catheter Ablation: Learning by Burning Continues

Clinical utility of automated assessment of left ventricular ejection fraction using artificial intelligence-assisted border detection

Trends in the use of percutaneous closure of patent foramen ovale and atrial septal defect in adults, 1998-2004

Translating Molecular Discoveries into New Therapies for Atherosclerosis

Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice

The multifaceted role of Notch in cardiac development and disease

A common variant on chromosome 9p21 affects the risk of myocardial infarction

Penn CVI Symposium May 28
UPCOMING EVENTS »
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Tomorrow's Events
 
7:30 am
Combined Cardiovascular and Cardiac Surgery Division Conference: Native Biopsy for Cardiomyopathy
4:00 pm
CVI Seminar Series: "The Nieman-Pick C Pathway: A Key Regulator of Cholesterol Homeostasis," Dr. Daniel Ory, Washington University School of Medicine
EVENT CALENDARS »
CVI Seminar Series »
Grand Rounds - HUP »
Grand Rounds - Presby »
RESEARCH PIPELINE »
Penn Heart Failure Study
PHFS is one of the largest genetic cohorts of heart failure patients in the U.S.
Learn More »