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Penn CME
Making History: We Are Medicine
Penn Cardiovascular Institute
Building Bridges, Accelerating Discovery, Advancing Care
Established in 2005, the Penn Cardiovascular Institute (Penn CVI) promotes transformational research in cardiovascular biology and medicine. Leveraging the expertise of scientists and clinicians across the University of Pennsylvania and the Health System through interdisciplinary research programs, the Penn CVI seamlessly integrates research, education and patient care. Learn more »

Research »

Penn Complex Genetics Initiative Personalized Medicine for the Heart?

Over the next five years 100,000 adult volunteers seeking patient care at the University of Pennsylvania Health System will be invited to join the Genetics of Cardiovascular and Metabolic Phenotypes Study, a DNA bank designed to identify genes involved in complex cardiovascular disorders. The study, part of the Complex Genetics Initiative, hopes to learn about the genetic causes of these diseases and how different people respond to medications and treatments.

About the CVI Complex Genetics Initiative »


6 ABC News Health Check Video - Jan. 7, 2009 New Heart Valves Without Open Surgery

The Hospital of the University of Pennsylvania is one of a handful of medical centers participating in the PARTNER trial - a new procedure that could change the lives of more than 120,000 heart patients. The procedure gives patients new heart valves, but without a major incision, and without general anesthesia.

About the PARTNER Trial at Penn »

Publications »

Journal of Clinical Investigation "Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development"
Journal of Clinical Investigation - June 2009
Diabetes "Apolipoprotein B but not Low-Density Lipoprotein Cholesterol is Associated with Coronary Artery Calcification in Type 2 Diabetic Caucasians"
Diabetes - June 2009
Developmental Biology "BMP type II receptor regulates positioning of outflow tract and remodeling of atrioventricular cushion during cardiogenesis"
Developmental Biology - May 2009
JAMA "Aspirin for the prevention of cardiovascular events in patients with peripheral artery disease: a meta-analysis of randomized trials"
JAMA - May 2009
Clinical Endocrinology "Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians"
Clinical Endocrinology - May 2009
American Heart Journal "Atheroprotective lipoprotein effects of a niacin-simvastatin combination compared to low- and high-dose simvastatin monotherapy"
American Heart Journal - April 2009
Proceedings of the National Academy of Sciences "Cardiomyocyte Cyclooxygenase-2 Influences Cardiac Rhythm and Function"
Proceedings of the National Academy of Sciences - April 2009
Journal of Thoracic and Cardiovascular Surgery "Early planned institution of biventricular mechanical circulatory support results in improved outcomes compared with delayed conversion of a left ventricular assist device to a biventricular assist device"
Journal of Thoracic and Cardiovascular Surgery - April 2009
"Evidence for co-regulation of myocardial gene expression by MEF2 and NFAT in human heart failure (PDF)"
Circulation: Cardiovascular Genetics - March 2009
Nature Genetics "Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants"
Nature Genetics - February 2009
Learn About the Penn
Heart and Vascular Center »

Advances in Medicine
Penn Heart and Vascular Center Puts Focus on the Patient (PDF)
June 15, 2009
NHLBI Funding Announcement
Systems Biology Collaborations
(RO1 / PAR-09-214) »

Upcoming Events »

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Penn CME
17th Annual State-of-the-Art Arrhythmia Symposium
Mon, Sep 14, 7:15 am

Penn CME
4th International Symposium on Ventricular Arrhythmias: Pathophysiology and Therapy
Fri, Oct 9, 7:00 am