Perelman School of Medicine at the University of Pennsylvania

Publications

2016

  1. He Z, Mitteer RA, Mou Y, Fan Yi. Chapter 5: Multimodality targeting of glioma cells. Glioblastoma, 1st edition (Ed. Brem S and Abdullah K), Elsevier, 2016, in press.
  2. Brem S, Wong E, Desai A, Fan Y, Pan E. Chapter 116: Angiogenesis and brain tumors. Youmans and Winn Neurological Surgery, 7th edition (Ed. Winn HR), Elsevier, 2016.
  3. Huang M, T Liu, Ma P, Mitteer RA, Zhang Z, Kim HJ, Yeo E, Zhang D, Cai P, Li C, Zhang L, Zhao B, Roccograndi L, O’Rourke DM, Dahmane N, Gong Y, Koumenis C, Fan Y. c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma. J Clin Invest. 2016; 126(5):1801-14. (PMID: 27043280)
  4. Zhang Y, He Q, Hu Z, Feng Y, Fan L, Tang Z, Yuan J, Shan W, Li C, Hu X, Tanyi JL, Fan Y, Huang Q, Montone K, Dang CV, Zhang L. Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer. Nat Struct Mol Biol. 2016; 23, 522–530. (PMID: 27111890)
  5. Zhang Y, Feng Y, Hu Z, Hu X, Yuan CX, Fan Y, Zhang L. Characterization of Long Noncoding RNA-Associated Proteins by RNA-Immunoprecipitation. Methods Mol Biol. 2016; 1402: 19-26. (PMID: 26721480)

2015

  1. Yan X, Hu Z, Feng Y, Hu X, Yuan J, Zhao SD, Zhang Y, Yang L, Shan W, He Q, Fan L, Kandalaft LE, Tanyi JL, Li C, Yuan CX, Zhang D, Yuan H, Hua K, Lu Y, Katsaros D, Huang Q, Montone K, Fan Y, Coukos G, Boyd J, Sood AK, Rebbeck T, Mills GB, Dang CV, Zhang L. Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers. Cancer Cell. 2015; 28(4): 529-40. (PMID: 26461095)
  2. Mitteer RA, Wang YL, Shah J, Gordon S, Fager M, Guardiola-Salmeron C, Carabe-Fernandez A*, and Fan Y*. Proton beam radiation induces DNA damage and cell apoptosis in glioma stem cells through reactive oxygen species. Sci Rep. 2015; 5: 13961. *, co-corresponding authors. (PMID: 26354413)
  3. Cai PQ, Lv XF, Tian L, Luo ZP, Mitteer RA Jr, Fan Y, Wu YP. CT Characterization of Duodenal Gastrointestinal Stromal Tumors. Am J Roentgenol. 2015; 204(5):988-93. (PMID: 25905932).
  4. Wu YP, Cai PQ, Tian L, Xu JH, Mitteer RA, Fan Y, Zhang ZF. Hypertrophic adenoids in patients with nasopharyngeal carcinoma: appearance at magnetic resonance imaging before and after treatment. Chin J Cancer. 2015; 34:4. (PMID: 25962737).

2014

  1. Zhao B, Yang D, Jiang J, Li J, Fan C, Huang M, Fan Y, Jin Y, Jin Y. Genome-wide mapping of miRNAs exxpresed in embryonic stem cells and pluripotent stem cells generated by different reprogramming strategies. BMC Genomics. 2014; 15:488. (PMID: 24942538).
  2. Eswarappa SM, Potdar AA, Koch WJ, Fan Y, Vasu K, Lindner D, Willard B, Graham LM, DiCorleto PE,Fox PL. Programmed Translational Readthrough Generates Antiangiogenic VEGF-Ax. Cell. 2014; 157(7):1605-1618. (PMID: 24949972).
  3. Fan Y, Potdar AA, Gong Y, Eswarappa SM, Donnola S, Lathia J, Hambardzumyan D, Rich JN, and Fox PL. Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through induction of HIF-1α. Nat Cell Biol. 2014; 16(5): 445-456. (PMID: 24747440).
  4. Gong Y, Zhao Y, Li Y, Fan Y, Hoover-Plow J. Plasminogen regulates cardiac repair after myocardial infraction through its non-canonical function in stem cell homing to the infarcted heart. J Am Coll Cardiol. 2014; 63(25): 2862-2872. (PMID: 24681141).

-2013

  1. Fan Y, Arif A, Gong Y, Jia J, Eswarappa SM, Willard B, Horowitz A, Graham LM, Penn MS, Fox PL. Stimulus-dependent phosphorylation of profilin-1 in angiogenesis. Nat Cell Biol. 2012; 14(10): 1046-1056. (PMID: 23000962). Cited by Faculty of 1,000.
  2. Fan Y, Eswarappa SM, Hitomi M, and Fox PL. Myo1c facilitates G-actin transport to the leading edge ofmigrating endothelial cells. J Cell Biol. 2012; 198(1): 47-55. (PMID: 22778278). Cited by Faculty of 1,000.
  3. Gong Y, Fan Y, Hoover-Plow J. Plasminogen regulates SDF-1/CXCR4-mediated hematopoietic stem cell mobilization by activation of matrix metalloproteinase-9. Arterioscler Thromb Vasc Biol. 2011; 31: 2035-2043. (PMID: 21719761).
  4. Fan Y, Gong Y, Ghosh P, Graham L, Fox PL. Spatial coordination of actin polymerization and ILK/Akt2 activity during endothelial cell migration. Dev Cell. 2009; 16: 661-674. (PMID: 19460343).
  5. Gong YQ, Fan Y, Wu DZ, Yang H, Hu ZB, Wang ZT. In vivo and in vitro evaluation of erianin, a novelanti-angiogenic agent. Eur J Cancer. 2004; 40(10): 1554-1565. (PMID: 15196540).
  6. Gong Y, Fan Y, Liu L, Wu D, Chang Z, Wang Z. Erianin induces a JNK/SAPK-dependent metabolic inhibition in human umbilical vein endothelial cells. In Vivo. 2004; 18(2): 223-228. (PMID: 15113050).
  7. Fan Y, Wu DZ, Gong YQ, Zhou JY, Hu ZB. Effects of calycosin on the impairment of barrier function induced by hypoxia in human umbilical vein endothelial cells. Eur J Pharmacol. 2003; 481(1): 33-44. (PMID:14637172).
  8. Fan Y, Wu DZ, Gong YQ, Xu R, Hu ZB. Metabolic responses induced by thrombin in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2002; 293(3): 979-985. (PMID: 12051756).