The Fifth International Workshop on Metabolic Imaging

Invited Speakers

Silvio Aime, Ph.D.

Professor of Chemistry, University of Torino, Italy

In Vivo and in Cells Metabolic Studies Using PHIP-SAH Hyperpolarized [1-¹³C] Pyruvate

Ashok Ajoy, Ph.D.

Postdoctoral Researcher, University of California, Berkeley

¹³C Hyperpolarization in Nanodiamonds: Applications to Spectroscopy and Imaging

Jan Henrik Ardenkjaer-Larson, Ph.D.

Professor of Electrical Engineering; Head of Center for Magnetic Resonance, Technical University of Denmark, Denmark

Recent Advances in Dissolution-DNP Polarization

James Bankson, Ph.D.

Professor of Imaging Physics, University of Texas, MD Anderson Cancer Center

Effects of B1 and Slice Profile Inhomogeneities on Dynamic HP ¹³C MRI

Nancy Boudreau, Ph.D.

Chief of Tumor Metastasis Branch, National Cancer Institute, National Institutes of Health

NCI's Vision/Initiatives Funding Opportunities in Cancer Biology

Eduard Chekmenev, Ph.D.

Associate Professor of Radiology, Radiological Sciences and Biomedical Engineering, Vanderbilt University

Parahydrogen Derived Polarization for Metabolic Imaging

Wei Chen, Ph.D.

Professor of Radiology and Biomedical Engineering, University of Minnesota

Quantitative Imaging of Brain Energy Metabolisms and Neuroenergetics at Ultrahigh Field

Murali K. Cherukuri, Ph.D.

Senior Investigator and Chief of Biophysics, National Cancer Institute, National Institutes of Health

Physiologic and Metabolic Imaging of Pancreatic Tumor Xenografts in Mice – Imaging Biomarkers to Guide Treatment

Peter Choyke, M.D.

Program Director of Molecular Imaging Program, National Cancer Institute, National Institutes of Health

Metabolic Oncologic Imaging: Why It Matters

Arnaud Comment, Ph.D.

Professor of Physics and Electrical Engineering, GE Healthcare

Hyperpolarized ¹³C MR Using Photo-induced Nonpersistent Radicals 

Charles Cunningham, Ph.D.

Associate Professor of Biology, Sunnybrook Research Institute, Canada

Excitation and Encoding in Hyperpolarized ¹³C MRI

Chi Dang, M.D., Ph.D.

Scientific Director, Ludwig Institute for Cancer Research; Professor, The Wistar Institute 

Cancer Imaging and Metabolic Therapy

Timothy R. DeGrado, Ph.D.

Professor of Radiology, Mayo Clinic

Noninvasive Evaluation of Metabolic Flexibility in Heart and Contracting Skeletal Muscle

Simon Duckett, Ph.D.

Director of the Center for Hyperpolarization in Magnetic Resonance, Professor of Chemistry, University of York, United Kingdom

Using SABRE to Hyperpolarize Pyruvate, Urea and Nicotinamide: Progress Towards In vivo Assessment

Mark Dunphy, M.D.

Nuclear Medicine Physician, Memorial Sloan Kettering Cancer Center

Fluoroglutamine PET/CT: First in-Human Trial

Sean B. Fain, Ph.D.

Professor of Medical Physics, Radiology and Biomedical Imaging, Director of the Image Analysis Core Facility, University of Wisconsin, Madison

Multi-scale Platform for Combined Magnetic Resonance Spectroscopy and Optical Imaging of Metabolism in 3D Cell Cultures

Henk de Feyter, Ph.D.

Assistant Professor of Radiology and Biomedical Imaging, Yale University 

Applications of Deuterium Magnetic Resonance Imaging to Gliomas      

Terence Gade, M.D., Ph.D.

Assistant Professor of Radiology and Cancer Biology, University of Pennsylvania

Imaging of Treatment Refractory, Latent Cellular Domains in Hepatocellular Carcinoma

Boyd Goodson, Ph.D.

Professor and Acting Associate Dean, College of Science, Southern Illinois University

New Approaches in SABRE: Cleavable Metabolic / pH-Sensing "Double Agents", and Preparation of Purified Agents via Heterogeneous Catalysis and Catalyst Immobilization 

Jeremy Gordon, Ph.D.

Senior Development Engineer, University of California, San Francisco

Extending Volumetric Coverage Using 3D Hyperpolarized C-13 EPI with Calibrationless Parallel Imaging

Robin de Graaf, Ph.D.

Professor of Radiology and Biomedical Imaging, Yale University

Deuterium Magnetic Imaging (DMI) — A Novel MR-based Method to Map Metabolism in 3D 

Christian Hilty, Ph.D.

Professor of Chemistry, Texas A&M University

New Developments on Obtaining Molecular Structure and Dynamics from Transient Hyperpolarization 

Paula M. Jacobs, Ph.D.

Associate Director of Cancer Imaging Program, National Cancer Institute, National Institutes of Health

The NCI IND of C-13 Pyruvate: A Resource for the Community 

Daniel Kelly, M.D.

Willard and Rhoda Ware Professor of Medicine; Director of Cardiovascular Institute, University of Pennsylvania

Feeding the Failing Heart

Kayvan Keshari, Ph.D.

Professor of Biomedical Engineering, Memorial Sloan Kettering Cancer Center

Toward Using In-cell HP MRS to Study Metabolism

Richard Kibbey, M.D., Ph.D.

Associate Professor of Medicine (Endocrinology) and of Cellular and Molecular Physiology, Yale University

¹³C Tracer Studies Using MIMOSA – A New Window on Quantitative Fluxomic

John Kurhanewicz, Ph.D.

Professor of Radiology and Biomedical Imaging; Pharmaceutical Chemistry; Urology, University of California, San Francisco

Current Status of Hyperpolarized ¹³C MR of Prostate Cancer Patients 

Christoffer Laustsen, Ph.D.

Associate Professor of Clinical Medicine, Aarhus University, Denmark

Hyperpolarized Functional and Metabolic Kidney Imaging

Robert Mach, Ph.D.

Britton Chance Professor of Radiology, University of Pennsylvania

Imaging Superoxide Levels in Tissues with PET

Craig Malloy, M.D.

Professor of Radiology, Chair in Cardiology, University of Texas, Southwestern

Probing Metabolic Networks in Human Subjects

Anthony Mancuso, Ph.D. 

Director of Laboratory for Quantitative Metabolomics, University of Pennsylvania

Methods for Examining Perfused Cancer Cells with Hyperpolarized Substrates Under Hypoxic Conditions

David Mankoff, M.D., Ph.D.

Gerd Muehllehner Professor of Radiology, PET Center Director, Vice-Chair of Research, Department of Radiology, University of Pennsylvania

Translating PET Cancer Metabolism Imaging to Patients: Beyond FDG

Charles Manning, Ph.D.

Director, Vanderbilt Center for Molecular Probes and Molecular Imaging Research, Professor of Radiology, Chemistry, Biomedical Engineering, Neurosurgery, and Chemical and Physical Biology, Vanderbilt University

PET Tracers to Guide Metabolically-targeted Therapy

Graeme Mason, Ph.D.

Professor of Radiology and Biomedical Imaging and of Psychiatry, Director of Metabolic Modeling, Director of Psychiatric MRS, Director of Neuroimaging Sciences Training Program, Chair of Magnetic Resonance Research Center Protocol Review Committee, Yale University

Metabolic Modeling of ¹³C Hyperpolarized Data for Studying Brain Metabolism and Neurotransmission 

Dirk Mayer, Ph.D.

Associate Professor of Diagnostic Radiology and Nuclear Medicine, Director of Metabolic Imaging in the Department of Diagnostic Radiology & Nuclear Medicine, University of Maryland

Applications of Hyperpolarized ¹³C MRI in Traumatic Brain Injury

Matthew Merritt, Ph.D. 

Assistant Professor of Radiology, University of Florida

Probing the Embden-Meyerhof Pathway in the Perfused Liver with HP Dihydroxyacetone

Jack Miller, Ph.D. 

Junior Research Fellow in Medical Physics, University of Oxford

Cardiac Carbon: Coils, Code and Challenges

Cornelius von Morze, Ph.D.

Development Engineer Sr., University of California, San Francisco

In Vivo Hyperpolarization Transfer in a Clinical MRI Scanner

Jonathan Murray

Managing Director, Research Circle Technology, GE Healthcare

Review of the Status and Challenges of Hyperpolarized Imaging

Mehrdad Pourfathi, M.S.

Ph.D. Candidate, University of Pennsylvania

Probing Lung Inflammatory Injury Using Hyperpolarized ¹³C MRI

Sabrina Ronen, Ph.D.

Professor of Radiology and Biomedical Imaging, Co-Director, Neuroimaging Research Interest Group, University of California, San Francisco

Phospholipid Metabolism in Mutant IDH1 Glioma –MRS Studies

Douglas Rothman, Ph.D.

Professor of Biomedical Engineering, Radiology and Biomedical Imaging, Yale University

What Hyperpolarized ¹³C MR Has to Achieve to be Used Routinely in Neurological and Psychiatric Research and Clinical Practice

Mitchell D. Schnall, M.D., Ph.D.

Eugene P. Pendergrass Professor of Radiology, Chairman of Radiology, University of Pennsylvania

Clinical Development Strategy for Hyperpolarized MR Imaging Techniques  

Rolf Schulte, Ph.D.

GE Healthcare

Optimum Acquisitions for Hyperpolarised Metabolic Imaging

Mark Sellmyer, M.D., Ph.D.

Professor of Radiology, University of Pennsylvania  

Taking Advantage of Orthogonal Metabolic Pathways for Targeted Infection Imaging

Alexander Shestov, Ph.D.

Professor of Radiology, University of Pennsylvania  

Metabolic Network Analysis in Cancer: Quantification of Flux

James Slater, Ph.D. 

Radiopharmaceutical Manager, University of California, San Francisco

Production of Filled Pharmacy Kits and Terminal Sterilization for Human Studies

Nathaniel Snyder, Ph.D.

Assistant Professor at the A.J. Drexel Autism Institute, Drexel University

Stable Isotope Tracing and Quantification of Compartmentalized Metabolism

Renuka Sriram, Ph.D. 

Postdoctoral Researcher, University of California, San Francisco

Development of Hyperpolarized ¹³C Metabolic Biomarkers of Prostate Cancer Aggressiveness – from Cells to Patient Derived Tissues

C.T. Tan, Ph.D.

Millipore Sigma

Review of Current Status of Hyperpolarized Agents for Research and Clinical Trials

Sui Seng Tee, Ph.D.

Research Fellow in Biochemisty, Memorial Sloan Kettering Cancer Center

Metabolic Imaging of Targeted Therapy in Preclinical Cancer Models

Marco Tessari, Ph.D.

Assistant Professor of Physics, Radboud University, Netherland

Para-hydrogen Induced Hyperpolarization for Quantitative NMR Analysis at Sub-Micromolar Concentrations

Thomas Theis, Ph.D.

Assistant Research Professor of Chemistry, Duke University

Hyperpolarization Chemistry and Spin Physics for Next Generation Biosensing

Mark Titus, Ph.D.

Associate Professor of Genitourinary Medical Oncology, University of Texas, MD Anderson Cancer Center

Hyperpolarized ¹³C MRI and Biomarkers of Androgen Signaling in Castrate-resistant Prostate Cancer

Matthew G. Vander Heiden, Ph.D.

Associate Professor of Biology, Associate Director of Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology

Role of Metabolismin Supporting Cancer Proliferation

Daniel Vigneron, Ph.D.

Professor of Radiology, Director of Hyperpolarized MRI Technology Resource Center, Director of Human Imaging Core Services, Director of Advanced Imaging Technologies SRG, University of California, San Francisco

Development and Translation of Hyperpolarized Carbon-13 MRI for Human Cancer and Brain Research

Shawn Wagner, Ph.D.

Technical Director, Small Animal MRI in the Biomedical Imaging Research Institute, Assistant Professor of Biomedical Sciences, Cedars-Sinai Medical Center

Development of a Preclinical PHIP Polarizer 

Warren S. Warren, Ph.D.

James B. Duke Professor of Chemistry, Duke University

Scaling Up SABRE Variants to Clinically Useful Levels with Biologically Interesting, Long-Lived Agents

Huiming Zhang, Ph.D.

Program Director of Imaging Technology Development Branch, National Cancer Institute, National Institutes of Health

Unmet Needs, Strategies and Opportunities in Cancer Imaging

Rong Zhou, Ph.D.

Research Associate Professor of Radiology, University of Pennsylvania

Imaging Cancer Glutamine Metabolism by PET and MRI