Lamitina Lab

Publications

Morton, E.A. and Lamitina, T. (2012) C. elegans HSF-1 is an essential nuclear protein that forms stress granule-like structures following heat shock. Aging Cell, In Press.

Shen XN, Sznitman J, Krajacic P, Lamitina T, Arratia PE. (2012) Undulatory locomotion of Caenorhabditis elegans on wet surfaces. Biophys. J., 102(12):2772-81

Lamitina T, Chevet E. (2012) To UPR...and beyond! A new role for a Bip/GRP78 protein in the control of antimicrobial peptide expression in the C. elegans epidermis. Virulence, 3(3), 238-40.

Moronetti, L., Dersh, D., Boccitto, M., Kalb, R.G., Lamitina, T. (2012) Stress and ageing induce distinct polyQ protein aggregation states. Proc Natl Acad Sci U S A, 109(26). 10587-92.

Predrag Krajacic, Xiaoning Shen, Prashant Purohit, Paulo Arratia, Todd Lamitina. (2012) Biomechanical Profiling of C. elegans Motility. Genetics, 191(3):1015-21.

MATLAB code for automated analysis of C. elegans biomechanics can be downloaded HERE.

He, S., Skirkanich, J., Moronetti, L., Lewis, R., Lamitina, T. (2012) The Cystic Fibrosis-associated ΔF508 mutation confers post-transcriptional destabilization on the C. elegans ABC transporter PGP-3. Disease Models and Mechanisms, 5(6):930-9.

Boccitto, M., Lamitina, T., Kalb, R.G. (2012) Daf-2 Signaling Modifies Mutant SOD1 Toxicity in C. elegans. PLoS One 7(3): e33494.

Li, F., Ryvkin, P., Dragomir, I., Desai, Y., Aiyer, S., Valladares, O., Yang, J., Bambina, S., Sabin, L., Murray, J.I., Lamitina, T., Raj, A., Cherry, S., Wang, L., Gregory, B.D. (2012) Global Analysis of RNA Secondary Structure in Two Metazoans. Cell Reports 1(1): 69-82.

Rohlfing, A.K., Miteva, Y., Moronetti, L., He, L., and Todd Lamitina (2011). The Caenorhabditis elegans mucin-like protein OSM-8 negatively regulates osmosensitive physiology via the transmembrane protein PTR-23. PLoS Genetics, 7(1): e1001267. [PDF].

Lee SD, Choi SY, Lim SW, Lamitina ST, Ho SN, Go WY, Kwon HM. (2011). TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: organic osmolyte-dependent and -independent pathways. Am. J. of Physiology, Mar;300(3):F707-15. [PDF].

Morton, E.A. and T. Lamitina (2010). A Suite of MATLAB-based Computational Tools for Automated Analysis of COPAS Biosort Data. BioTechniques Vol. 48, No. 6, pp. 25-30 . [PDF]. MATLAB code for automated analysis of COPAS Biosort data can be downloaded here.

Rohlfing, A.K., Miteva, Y., Hannenhalli, S., Lamitina, T. (2010). Genetic and Physiological Activation of Osmosensitive Gene Expression Mimics Transcriptional Signatures of Pathogen Infection in C. elegans. PLoS One 5(2): e9010. doi:10.1371/journal.pone.0009010. [PDF]

Snitzman, J., Purohit, P, Krajacic, P., Lamitina, T., Arratia, P.E. (2009). Material properties of Caenorhabditis elegans swimming at low Reynolds number. Biophysical Journal, Feb 17;98(4):617-26. [PDF]

Krajacic P, Hermanowski J, Lozynska O, Khurana TS, Lamitina T. (2009) The C. elegans Dysferlin homolog fer-1 is expressed in muscle and fer-1 mutations initiate altered gene expression of muscle enriched genes. Physiol Genomics, 2009. 40(1): p. 8-14. [PDF]

Lamitina, T., Cherry S. (2008). Dangerous liaisons: the apoptotic engulfment receptor CED-1 links innate immunity to the unfolded protein response. Dev. Cell, Jul;15(1)3-4.

Junio, AB, Li, X, Massey, HC, Nolan, TJ, Lamitina, S. Todd, Sundaram, MV, Lok, JB. (2008). Strongyloides stercoralis: Cell-and tissues-specific transgene expression and co-transformation with vector constructs incorporating a common multifunctional 3'UTR. Exp Parasitol. 118(2):253-65. [PDF]

Huang, C.G., Lamitina, T., Agre, P., Strange, K. (2007). Functional analysis of the aquaporin gene family in C. elegans. Am. J. Physiol. Cell Physiol. May;292(5):C1867-73. Epub 2007 Jan 17 [PDF]

Lamitina, T. (2006). Functional genomic approaches in C. elegans. Methods Mol. Biol. 2006; 351:127-138.

Yan, X, Xing,J., Lorin-Nebell,C., Estevez,A.Y., Lamitina,T., Strange,K. (2006). Function of a STIM1 homolog in C. elegans: evidence that store-operated Ca2+ entry is not essential for oscillatory Ca2+ signaling and ER Ca2+ homeostasis. J. Gen Phys. 128(4):443-59. Cited by Faculty of 1000. [PDF]

Lamitina T. Functional Genomic Approaches in C. elegans. Methods Mol Biol 351: 127-138, 2006. [PDF]

Lamitina T, Huang CG and Strange K. Genome-wide RNAi screening identifies protein damage as a regulator of osmoprotective gene expression. Proc Natl Acad Sci U S A 103: 12173-12178, 2006. Cited by Faculty of 1000. [PDF]

Huang CG, Agre P, Strange K and Lamitina T. Isolation of C. elegans Deletion Mutants Following ENU Mutagenesis and Thermostable Restriction Enzyme PCR Screening. Mol Biotechnol 32: 83-86, 2006. [PDF]

Lamitina ST and Strange K. Transcriptional targets of the DAF-16 insulin signaling pathwayprotect C. elegans from extreme hypertonic stress. Am J Physiol Cell Physiol 2004. [PDF]

Lamitina ST, Morrison R, Moeckel GW and Strange K. Adaptation of the nematode Caenorhabditis elegans to extreme osmotic stress. Am J Physiol Cell Physiol 286: C785-C791, 2004. [PDF]