Daniel D. Langleben, M.D.
(Assistant Professor, Psychiatry)

Contents


Education and Training

  • B.S. - 1983
  • M.D. - 1989
  • The Mount Sinai Hospital, New York, 1991-1994, Adult Psychiatry
  • The Mount Sinai Hospital, New York, 1994-1995, Diagnostic Radiology
  • University of California San Francisco, 1995-1997, Addiction Psychiatry
  • Stanford University Medical Center, 1997-1999, Nuclear Medicine

Publications

Papers

Langleben DD, Dattilio FM, and Gutheil TG. True lies: delusions and lie-detection technology (PDF File). The Journal of Psychiatry & Law. 2006 Fall; 34(3):351-370.

Langleben DD, Monterosso, J., Elman, I, Ash, B, Krikorian, G, Austin, G. The effect of methylphenidate on the performance of the Stroop Color Word Interference Test in children with Attention Deficit Hyperactivity Disorder (PDF file). Psychiatry Research. 2006 March;141(3):315-320.

Langleben DD, Loughead JW, Bilker WB, Ruparel K, Childress AR, Busch SI, Gur RC. Telling truth from lie in individual subjects with fast event-related fMRI (PDF file). Hum Brain Mapp. 2005 Dec;26(4):262-72.

Davatzikos C, Ruparel K, Fan Y, Shen DG, Acharyya M, Loughead JW, Gur RC, Langleben DD. Classifying spatial patterns of brain activity with machine learning methods: Application to lie detection (PDF file). Neuroimage, 2005 Nov;28(3):663-8.

Wolpe PR, Foster KR, Langleben DD. Emerging neurotechnologies for lie-detection: promises and perils (PDF file). Am J Bioeth, 2005 Spring;5(2):39-49.

Platek SM, Loughead JW, Gur RC, Busch S, Ruparel K, Phend N, Panyavin IS, Langleben DD. Neural substrates for functionally discriminating self-face from personally familiar faces (PDF file). Hum Brain Mapp, 2006 Feb;27(2): 91-8.

Bloomer CW, Langleben DD, Meyerhoff DJ. Magnetic resonance detects brainstem changes in chronic, active heavy drinkers (PDF file). Psychiatry Res, 2004 Dec 30;132(3):209-18.

Elman I, Rott D, Green AI, Langleben DD, Lukas SE, Goldstein DS, Breier A. Effects of pharmacological doses of 2-deoxyglucose on plasma catecholamines and glucose levels in patients with schizophrenia (PDF file). Psychopharmacology (Berl), 2004 Nov;176(3-4):369-75.

Szobot CM, Ketzer C, Cunha RD, Parente MA, Langleben DD, Acton PD, Kapczinski F, Rohde LA. The acute effect of methylphenidate on cerebral blood flow in boys with attention-deficit/hyperactivity disorder (PDF file). Eur J Nucl Med Mol Imaging, 2003 Mar;30(3):423-6.

Langleben DD, Acton PD, Austin G, Elman I, Krikorian G, Monterosso JR, Portnoy O, Ridlehuber HW, Strauss HW. Effects of Methylphenidate Discontinuation on Cerebral Blood Flow in Prepubescent Boys with Attention Deficit Hyperactivity Disorder (PDF file). J Nucl Med. 2002 Dec; 43(12):1624-1629. Commentary by F. X. Castellanos (PDF file)

Langleben D, Schroeder L, Maldjian J, Gur R, McDonald S, Ragland, JD, O’Brien CP, Childress AR. Brain activity during simulated deception: An event-related functional magnetic resonance study (PDF file). Neuroimage 2002, Mar; 15(3):727-732.

Langleben, D, Austin G, Goris M, Strauss H. W. Interhemispheric asymmetry of regional cerebral blood flow in prepubescent boys with Attention Deficit Hyperactivity Disorder (PDF file). Nuclear Medicine Commun, 2001 Dec; 22(12):1333-40.

Krausz Y, Ikeda DM, Jadvar H, Langleben D, Birdwell R, Strauss HW. Non-visualization of sentinel lymph node in patients with breast cancer. Nucl Med Commun. 2001 Jan; 22(1):25-32.

Langleben DD, Segall GM. PET in differentiation of recurrent brain tumor from radiation injury (PDF file). J Nucl Med. 2000 Nov; 41(11):1861-7.

Langleben M, Langleben D: " Iterational structures in Anomalous Texts." In: Organization in Discourse. Proceedings from the Turku Conference", Anglicana Turkuensia 14, 329-340, Turku, Finland, 1995.

Selected Abstracts

Langleben, D.D., Busch, S.I., Sciortino, N., Holloway, M.B., Pratwadi, R., Wang, J., Wang, Z., Detre, J.A., O’Brien, C.P., Childress, A.R. Methadone Reduces Limbic System Response to Salient Drug Cues in Patients with a History of Heroin Dependence. Presented at the 35th annual meeting of the Society for Neuroscience. Washington, D.C. November 2005.

Loughead, J., Busch, S., Phend, N., Childress, A.R., Gur, R.C., & Langleben, D.D. Brain activity during deception: an event-related functional MRI study.  Human Brain Mapping.  Budapest, Hungary. June 2004.

Langleben, D.D., Busch, S., Sciortino, N., Listerud, J., Wang, J.J., Detre, J., Childress, A.R., & O’Brien, C.P. Gender differences in brain activity during heroin related cues in opiate-dependent subjects: a perfusion functional magnetic resonance imaging (fMRI) study. Presentation given at the annual meeting of the College on Problems of Drug Dependence. San Juan, Puerto Rico. June 2004.

Merritt, C.K., Busch, S.I., Nioka, S., Weissman A.S., Zak, P.D., & Langleben, D.D. Are the brain correlates of responding yes and no different? Presentation given at the 33rd annual meeting of the Society for Neuroscience Conference. New Orleans, LA. November 2003.

Invited Talks
 

"Lie Detection with fMRI". Functional Imaging Laboratory. University College London, England. September 29, 2007.

"The Truth about Lie Detection with fMRI". Autumn School in Cognitive Neuroscience. University of Oxford, England. September 25, 2007.

"Naltrexone Modulates Brain Response to Drug Cues in Abstinent Heroin Addicts". 100th Jubilee Conference of the V.M. Bekhterev Psychoneurological Institute. St. Petersburg, Russia. May, 2007. Bekhterev Institute

"Studies of Deception with Functional MRI and their Application to Lie-Detection". Gottlieb Daimler- And Karl Benz-Foundation: 11th Berlin Colloquium. Berlin, Germany. May, 2007. Statements of the Speakers

"Perfusion magnetic resonance imaging of opiate dependent patients exposed to drug-related cues".  College on Problems of Drug Dependence. Orlando, FL. June 2005.

"Brain Imaging Technologies".  8th National Undergraduate Bioethics Conference. April 2, 2005.

"Imaging deception with fMRI: The effects of salience and ecological relevance".  Society for Neuroscience Conference. San Diego, CA. November 2004.

"FMRI of deception".  McLean/Harvard Hospital Neuroscience Series. April 21, 2004.

"Functional MRI of craving".  European College of Psychopharmacology, Prague, the Czech Republic. September 21, 2003.

"Brain correlates of intentional deception".  University of Pennsylvania Health System Administrative Forum, February 13, 2003.

"Forensic brain imaging".  The Wharton School of Business Administration, University of Pennsylvania, January 2003.

Projects

  • Magnetic Resonance Imaging for the detection of Intentional Deception funded by the Army Office of Research.
  • Functional Neuroimaging of Cue-Induced Heroin Craving funded by the National Institute on Drug Abuse-K23.
  • Functional MRI of Brain Response to Anti-Smoking Advertising funded by the National Cancer Institute-5-P50.

Media Coverage

NPR Part 3: Listen to Audio PDF
NPR Part 2: Listen to Audio PDF
NPR Part 1: Listen to Audio PDF
PBS Wired Science - Lie Detectors
The New Yorker: The Mail: Telling Lies
The New Yorker - Duped
New York Times Magazine - The Brain on the Stand
Washington Post - Brain on Fire
Time Magazine - How to spot a Liar
San Francisco Chronicle: Lies Wide Open - Researchers say technology can show when and how a lie is created inside the brain
Nature: Lure of Lie Detectors Spook Ethicists
Wired Magazine: How Brain Scans are Reinventing the Science of Lie Detection
The New York Times: Looking for the Lie
Philadelphia Magazine: The End of the Lie
Nature: Brain Imaging Ready to Detect Terrorists, Say Neuroscientists
Newsday: Your Brain Can't Handle the Lies
Popular Science: Liar Liar Pants on Fire
Nature: The Truth About Lying
The Economist: Making Windows in Men's Souls
Nature: Brain Imaging Could Spot Liars
The Pennsylvania Gazette: Whose Minding the Brain
Scientific American: Mind Readers
PBS: Brain Imaging
National Post: Brain Scan Can Detect Lies, Researchers Find
Society for Neuroscience: Understanding Human Behavior
San Francisco Chronicle: Study Shows that Brain Scan Detects Patterns of Neural Activity When Someone Lies
New York Times: Zeroing in a Lie's Homebase
Washington Post: Researchers Find that Brain Scans can be a Powerful Tool in Detecing Lies
Die Welt
BBC News: Your Cheating Brain
ABC News Tonight with Peter Jennings
Scientific American: MRI Study Shows Lying Brains Look Different

Links

Last updated on 10/31/07

 
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