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Yair Argon - After attending Medical School in Jerusalem, Dr. Argon obtained a Ph.D. in Biochemistry from Harvard University where he studied cell-cell interactions in the model genetic organism C. elegans. His postdoctoral research, conducted under the mentorship of Dr. C. Milstein in the Lab of Molecular Biology at Cambridge, UK, involved mutations that block antibody secretion. Dr. Argon became an Assistant Professor of Immunology at Duke University in 1985 and moved to the Department of Pathology at the University of Chicago in 1994. There, Dr. Argon was director of the graduate program in Pathology, Vice Chair of the Committee on Immunology and Chair of the medical center committee on research core facilities. He has been a Professor of Pathology and Laboratory Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia since 2003, where he serves as Chief of the Division of Cell Pathology. His research focuses on the roles that molecular chaperones play in the function of immune cells.
Tobias Baumgart – Dr. Baumgart obtained a Ph.D. degree from the Johannes Gutenberg University in Mainz, Germany. Under the supervision of Andreas Offenhaeusser and Wolfgang Knoll of the Max Planck Institute for Polymer Research, he studied solid supported self-assembly of Langmuir-Blodgett type lipid mono- and bilayer membranes, using various fluorescence and surface analytical techniques for physicochemical characterization. His postdoctoral training in Applied and Engineering Physics at Cornell University in the laboratory of Watt Webb included fluorescence spectroscopy and imaging techniques, imaging equipment design and the development of software algorithms for quantitative image analysis, including single particle tracking. There, Dr. Baumgart collaborated with immunologists Barbara Baird and David Holowka on immunologically relevant questions. An Assistant Professor of Chemistry at the University of Pennsylvania since 2005, Dr. Baumgart continues to explore the biophysical properties and function of biological membranes, particularly as they relate to immune cell signaling and intracellular membrane sorting.
Janis K. Burkhardt – Dr. Burkhardt received a Bachelors degree in Biology from Washington University in 1983, and a Ph.D. in Immunology from Duke in 1989, where she worked on protein trafficking in lymphocytes. During her post-doctoral studies with Bernard Amos at Duke and Gareth Griffiths at the European Molecular Biology Lab in Heidelberg Germany, she focused on cytoskeletal aspects of cytotoxicity and phagocytosis. She joined the faculty of the Department of Pathology at the University of Chicago in 1996, and moved in 2002 to the Department of Pathology and Laboratory Medicine at The Children’s Hospital of Philadelphia and the University of Pennsylvania, where she now holds the Evelyn and George Willing Chair in Pathology Research. Dr. Burkhardt’s research focuses on cytoskeletal aspects of T cell and dendritic cell function. She has directed microscopy core facilities at Chicago and Penn, and serves on oversight committees of three microscopy facilities on the Penn campus. In 2008, she founded the IMIG group to advance the use of microscopy among Penn researchers.
Bruce D. Freedman – Dr. Freedman obtained his Bachelors degree in Biology from Dickinson College in 1980 followed by a Master of Science in Animal Nutrition from Penn State University in 1983. Accepted into the combined V.M.D., Ph.D. degree program at the University of Pennsylvania, Dr. Freedman completed his Veterinary Medical training in 1987 and obtained a Ph.D. in Physiology in 1992. Following postdoctoral studies under Glen Gaulton and Mike Kotlikoff, Dr. Freedman established his own laboratory at the University of Pennsylvania School of Veterinary Medicine, Department of Pathobiology. Dr. Freedman currently directs the Penn School of Veterinary Medicine Imaging Facility, and is committed to advancing the use of high-end optical methods for subcellular and intravital imaging by researchers across the Penn community. Dr. Freedman’s lab focuses on mechanisms of calcium signaling within lymphocytes and macrophages, utilizing a range of optical, electrophysiological, and molecular approaches.
Christopher A. Hunter - Dr. Hunter received his B.Sc. and Ph.D. degrees in zoology and parasitology from the University of Glasgow before completing his training in the immunology of infectious disease at Stanford University. He joined the faculty of the University of Pennsylvania School of Veterinary Medicine in 1996, and in 2007 was named Chairman of the Department of Pathobiology. At Penn, Dr. Hunter has continued to pursue his interest in the immunobiology of parasitic infections, focusing on immunologic responses to Toxoplasma gondii. His work includes imaging specific immune populations (T cells, DC, astrocytes, macrophages) involved in this response.
Gary A. Koretzky – Dr. Koretzky graduated from Cornell University and received his M.D. and Ph.D. (Immunology) degrees from the University of Pennsylvania in 1984. Upon completion of a residency in Internal Medicine and a fellowship in Rheumatology at UCSF, Dr. Koretzky began his independent career as a physician-scientist at the University of Iowa. Dr. Koretzky returned to the University of Pennsylvania in 1999 as the Director of the Signal Transduction Program of the Abramson Family Cancer Research Institute. He currently serves as Francis C. Wood Professor of Medicine and Vice Chair for Research and Chief Scientific Officer of the Department of Medicine. His research focuses on the integration of signaling pathways in hematopoietic cells and their effects on immune cell function and development. Dr. Koretzky is a member of the Immunology and Cell and Molecular Biology graduate groups at Penn and serves at the senior Associate Chair of Penn’s M.D., Ph.D. program. Dr. Koretzky is past President of the American Society of Clinical Investigation and serves as Editor in Chief of Immunological Reviews and Deputy Editor of the Journal of Clinical Investigation.
Jordan S. Orange – Dr. Orange received his A.B., M.D. and Ph.D. from Brown University. Under the guidance of Christine Biron, Dr. Orange’s doctoral research focused on the NK cell response to viral infection. He subsequently performed post-doctoral research fellowships on cytoskeletal biology and the NK cell immunological synapse in the laboratories of Raif Geha and Jack Strominger, both at Harvard University. Thereafter, Dr. Orange started his own laboratory devoted to the Natural Killer cell immunological synapse and inborn defects of human immunity. Dr. Orange is presently an Associate Professor of Pediatrics at the Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine. In 2009. he was awarded the Judson Daland Prize by the American Philosophical Society.
Steven L. Reiner – Dr. Reiner received a B.A. in philosophy from Haverford College in 1982 and an M.D. degree from Duke University in 1985. He is clinically trained in internal medicine and infectious diseases. Following postdoctoral research at the University of California San Francisco in the laboratory of Richard Locksley, Dr. Reiner took his first faculty appointment in the Gwen Knapp Center for Lupus and Immunology Research at The University of Chicago in 1994. In 1999, he became one of the founding members of the Abramson Family Cancer Research Institute of the University of Pennsylvania. His research focuses on understanding the signaling and transcriptional mechanisms involved in heritable changes in gene expression of T lymphocytes during mammalian immune responses. His laboratory’s study on asymmetric cell division of T lymphocytes was named one of the top 10 scientific breakthroughs of 2007 by Science magazine. Dr. Reiner was recently named Director of the Penn Institute for Immunology.
Lingli Zhang – Dr. Zhang received her Ph.D. in Neuroscience from the University of Pennsylvania in 2005. She attended the quantitative light microscopy course at the Marine Biological Laboratory in Woods Hole and obtained training in FRET at the Keck Center for Cellular Imaging at the University of Virginia. Dr. Zhang’s imaging experience includes calcium imaging, chloride imaging, multiphoton imaging-based mapping of neuronal circuitry, and fluorescence uncaging technology. Upon completion of her post-doctoral work in Neuroscience in 2008, Dr. Zhang joined the University of Pennsylvania School of Veterinary Medicine Imaging facility as the technical director.