Carol Deutsch, PhD

Professor of Physiology

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Faculty Spotlight


The Deutsch laboratory has had a long-standing interest in the biophysics and physiology of potassium ion channels. Carol Deutsch, PhD is an expert in the electrophysiology of Kv potassium channels, publishing in this area for many years. More recently she instigated and pioneered comprehensive investigations of Kv biogenesis and the physico-chemical properties of the ribosomal exit tunnel. The Deutsch laboratory is the only one studying the early stages of folding of Kv proteins and one of a few laboratories studying the functional biophysical properties of the exit tunnel.

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Zhe Lu, MD, PhD

Professor of Physiology

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Faculty Spotlight


The Lu lab is interested in the detailed mechanisms and regulation of ion channel permeation and gating. Zhe Lu, MD, PhD is an internationally recognized leader in studies of potassium channel ion permeation. In particular, the inward rectifier channels, where he has provided fundamental insights into the mechanisms of rectification, which have critical physiological implications. He has also made important discoveries regarding the roles of the lipid membrane and its modifications in regulating ion channel function, including potassium channels as well as the CFTR anion channel that when mutated causes cystic fibrosis.

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Benjamin Prosser, PhD

Assistant Professor of Physiology

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Faculty Spotlight


Benjamin Prosser, Ph.D. is a newly appointed Assistant Professor of Physiology. During his graduate and post-doctoral training, Ben investigated the mechanistic underpinnings of key problems in muscle physiology. His work has bridged several disciplines, departments and institutes, including physiology, cell biology, cardiovascular research, biophysics and engineering. He is an emerging leader in new, exciting aspects of the molecular physiology of cardiomyocyte function and signaling; with strong relevance for understanding basic mechanisms of cardiac function, with clear translational implications. Additionally, to achieve his research goals, he is developing and utilizing state-of-the-art imaging, as well as biophysical and biochemical technologies.

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J. Kevin Foskett, PhD

Isaac Ott Professor

Chair of Physiology

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From Our Chair


Welcome to the Department of Physiology in the Perelman School of Medicine at the University of Pennsylvania. Our Department is devoted to research, training, and education and strives to push the boundaries of scientific discovery and academic development. The Department’s internationally recognized faculty, in conjunction with post-doctoral fellows, graduate students, and staff, use innovative tools to uncover physical and chemical mechanisms of biological processes. Our frontiers span the molecular to organ level to determine how the human body functions in health and disease.

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Contact


  • 700 Clinical Research Building

  • 415 Curie Boulevard

  • Philadelphia, PA 19104-6085

  • tel: 215-898-8725

  • fax: 215-573-2273

  • phys@mail.med.upenn.edu