Lin

Lin Guo is a post-doctoral researcher. She received her bachelor’s degree in Chemistry from Peking University in 2005 and her Ph.D. in Chemistry in 2011 from The University of Pennsylvania where she developed spectroscopic methods to study protein folding and peptide-membrane interaction.

Publications

Y-H. Wang, A. Collins, L. Guo, K. B. Smith-Dupont, F. Gai, T. Svitkina and P. A. Janmey. Divalent cation-induced cluster formation by polyphosphoinositides in model membranes. J. Am. Chem. Soc. 2012, 134, 3387-3395.

L. Guo, K. B. Smith-Dupont and F. Gai. Diffusion as a probe of peptide-induced membrane domain formation. Biochemistry 2011, 50, 2291-2297.

J. M. G. Rogers*, A. Polishchuk*, L. Guo*, J. Wang, W. F. DeGrado and F. Gai. Photoinduced electron transfer and fluorophore motion as a probe of the conformational dynamics of membrane proteins: application to the influenza A M2 proton channel. Langmuir 2011, 27, 3815-3821. (*Equal Contribution)

L. Guo and F. Gai. Heterogeneous diffusion of a membrane-bound pHLIP peptide. Biophys. J. 2010, 98, 2914-2922.

K. B. Smith-Dupont*, L. Guo* and F. Gai. Diffusion as a probe of the heterogeneity of antimicrobial peptide-membrane interactions. Biochemistry 2010, 49, 4672-4678. (*Equal Contribution)

L. Guo, J. H. Park, T. Lee, P. Chowdhury, M. Lim and F. Gai. Probing the role of hydration in the unfolding transitions of carbonmonoxy myoglobin and apomyoglobin. J. Phys. Chem. B 2009, 113, 6158-6163.

S. Mukherjee, M. Waegele, P. Chowdhury, L. Guo and F. Gai. Effect of macromolecular crowding on the folding kinetics of protein secondary structures. J. Mol. Biol. 2009, 393, 227-236.

L. Guo, P. Chowdhury, J. M. Glasscock and F. Gai. Denaturant induced expansion and compaction of a multi-domain protein: IgG. J. Mol. Biol. 2008, 384, 1029-1036.

S. Yang, H. Wang, L. Guo, Y. Liu and A. Cao. Interaction of fullerenol with lysozyme investigated by experimental and computational approaches. Nanotechnology 2008, 19, 395101-395107.

L. Guo, P. Chowdhury, J. Y. Fang and F. Gai. Heterogeneous and anomalous diffusion inside lipid tubules.  J. Phys. Chem. B 2007, 111, 14244-14249.

 

 

 

 

 

 

People



 
Department of Biochemistry & Biophysics
p3
University of Pennsylvania