Meredith Jackrel is a post-doctoral researcher. She received her Ph.D. in Chemistry from Yale University in 2010 and graduated from the College of New Jersey with a BS in Chemistry in 2004. In 2011, Meredith won an American Heart Association Post-Doctoral Fellowship!
Jackrel, M.E., M.E. DeSantis, B.A. Martinez, L.M. Castellano, R.M. Stewart, K.A. Caldwell, G.A. Caldwell, and J. Shorter. (2014). Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events. Cell. 156:170–182. pdf file link
DeSantis, M.E., E.H. Leung, E.A. Sweeny, M.E. Jackrel, M. Cushman-Nick, A. Neuhaus-Follini, S. Vashist, M.A. Sochor, M.N. Knight, and J. Shorter. (2012). Operational Plasticity Enables Hsp104 to Disaggregate Diverse Amyloid and Non-Amyloid Clients. Cell. 151:778-793. pdf file link
Jackrel, M.E. and J. Shorter. (2011). Shock and awe: unleashing the heat shock response to treat Huntington disease. J. Clin. Invest. 121(8): 2972-2975. pdf file link
Jackrel, M.E., A.L. Cortajarena, T.Y. Liu and L.Regan. (2010). Screening libraries to identify proteins with desired binding activities using a split-GFP reassembly assay. ACS Chem Biol. 5 (6): 553–562. pdf file link
Jackrel, M.E., R. Valverde and L. Regan. (2009) Redesign of a protein - peptide interaction: characterization and applications. Protein Science. 18(4): 762-74. pdf file link
Champion, E.A., B.H. Lane, M.E. Jackrel, L.Regan and S.J. Baserga. (2008). A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing. Mol Cell Biol. 28(21): 6547-56. pdf file link