Executive Difficulty in
Parkinson's Dementia
Murray Grossman, MD, PhD - Project Leader
Executive resources like planning and organization are crucial for day-to-day conversation. Without these resources, communicative efficacy is lost. There are major consequences to these difficulties, and activities of daily living suffer immensely. In our project, we will be examining the organization of discourse. |
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| There are large-scale speech samples. We will also be examining the comprehension of organizational components of scripts, that is, story-like stimuli. In addition to studies of difficulties in patients, we will be assessing the neural basis for these difficulties by correlating their speech and comprehension impairments with structural MRI studies of the brain. Finally, we will be using fMRI (functional magnetic resonance imaging) to assess the neural basis for these organizational components of speech and comprehension in healthy young adults. |
This study is being conducted at the Hospital of the University of Pennsylvania, 3400 Spruce Street.
Additional Parkinson’s ongoing studies at Penn
There are additional Parkinson’s and movement disorder studies ongoing at Pennsylvania Hospital. For a listing of these studies with contact information, please visit http://www.uphs.upenn.edu/neuro/research/trials/parkinsons/index.html.
