Collaborators
| CONTACT INFO | PROJECT SUMMARY | |
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Professor Greg Van Duyne Department of Biochemistry & Biophysics University of Pensylvania Philadelphia, PA 19104-6059 vanduyne@mail.med.upenn.edu |
A project with graduate student Katie Sacharan and Dr. Kathy Valentine in collaboration with Professor Cecilia Tommos. We are assisting in the structural charaterization of a SMN protein complex that has resisted crystallization. |
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Professor Kim Sharp Department of Biochemistry & Biophysics University of Pensylvania Philadelphia, PA 19104-6059 sharpk@mail.med.upenn.edu |
A project with graduate student Kyle Harpole. We are providing experimental benchmarks for Sharp's novel "pump-probe" computational approach to illuminating coupled dynamics in proteins. |
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Professor Walter Englander |
A project with graduate student Ben Walters. We are helping in the measurement of native state hydrogen exchange in the maltose binding protein. The aim is to discover the patterns of cooperative substructure in larger proteins using the site-resolution provided by three dimensional solution NMR methods. |
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Professor Bertrand Garcia-Moreno |
A project with postdoctoral associate Dr. Nathaniel Nucci and undergraduate Nimu Sidhu. We are employing reverse micelle encapsulation to explore several anticipated effects of confinement, including protein hydration and dynamics. |
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Professor Mike Summers Department of Chemistry & Biochemistry University of Maryland Baltimore County Howard Hughes Medical Institute 1000 Hilltop Circle Baltimore, MD 21250 summers@hhmi.umbc.edu www.hhmi.umbc.edu |
A project with Dr. Kathy Valentine. Begun by former postdoc Dr. Ron Peterson, we are continuing our efforts to employ reverse micellle encapusulation to study the role of lipid-anchoring by proteins in signaling and assembly of protein complexes at the membrane. Here we are focusing on the HIV matrix protein and its role in identifying the plasma membrane and initiating the assembly of the immature virion particle. |
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Professor Pei Zhou Department of Biochemistry Duke University Durham, NC peizhou@biochem.duke.edu |
A project with Professor Cecilia Tommos, postdotoral associate Dr. Nathaniel Nucci. We are employing reverse micelle encapsulation to improve the high resolution solution NMR properties of several proteins from the Zhou research group. |
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Professor Jim Ames Department of Chemistry University of California, Davis jbames@ucdavis.edu |
A project with Dr. Kathy Valentine and graduate student Sarah Chung. We are continuing our efforts to employ reverse micellle encapusulation to study the role of lipid-anchoring by proteins in signaling and assembly of protein complexes at the membrane. Here we are focusing on the calcium-regulated recovrin molecule. |
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Professor Sharon Campbell Department of Biochemistry University of North Carolina Chapel HIll, NC sharon_campbell@med.unc.edu |
A project with Dr. Kathy Valentine. We are employing reverse micelle encapsulation to improve the high resolution solution NMR properties of a membrane associated protein from the Campbell research group. |
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Professor Andreas Pluckthun |
With Dr. Sabrina Bedard and Adam Seitz, we are exploring the utility of reverse micelle encapsulation for the characterization of G-protein coupled receptors by solution NMR methods. |