2017

NOVEMBER

Dongming and Deirdre’s paper showing that the output of protein-coding genes shifts to circular RNAs when the pre-mRNA processing machinery is limiting is published in Molecular Cell.

The Wilusz lab presents its latest work at the annual retreat of the Department of Biochemistry & Biophysics in the Poconos.

Mike and Deirdre present talks at the Biochemistry & Biophysics Friday Research Discussions series.

OCTOBER

Mike’s review on non-AUG translation is published in Genes & Development.

Postdoc Meisheng Xiao joins the group.

Research specialist Chike Nwaezeapu joins the group.

Chuan, Deirdre, and Mike present their data at the Penn Biomedical Postdoctoral Research Symposium. Deirdre wins the Best Poster Award.

Jeremy presents a poster at the Cold Spring Harbor meeting on Forty Years of mRNA Splicing: From Discovery to Therapeutics.

SEPTEMBER

Jeremy presents a talk on circular RNA biogenesis in Oxford, UK at the EMBO Workshop on Regulation of RNA 3’ end formation across eukaryotic genomes.

Mike is awarded a K99/R00 Pathway to Independence Award from NIH.

Deirdre presents a poster at the Cold Spring Harbor meeting on Mechanisms of Eukaryotic Transcription.

Mike presents a poster at the EMBO conference on Protein Synthesis and Translational Control in Heidelberg, Germany.

AUGUST

A collaborative R01 with Aravind Asokan’s lab at UNC to express circular RNAs in animal models is funded by NINDS.

Deirdre and Dongming’s book chapter on circular RNA expression plasmids is published in Methods in Molecular Biology.

US Patent 9,717,749 awarded for methods to produce stable non-polyadenylated RNAs.

JULY

Jeremy attended the Rita Allen Foundation Scholars summer workshop that was organized by the Alan Alda Center for Communicating Science.

Jeremy is quoted in a news piece on circular RNAs in The Scientist.

JUNE

Jeremy gives a talk on circular RNAs at the RNA Society Annual Meeting in Prague, Czech Republic.

Collaborative work with Howard Chang’s lab on immune surveillance of circular RNAs is published in Molecular Cell.

MAY

Jeremy gives an invited talk at the Abramson Cancer Center Symposium on RNA Biology & Cancer.

Chuan, Deirdre, Mike, and Jeremy attend the NCI RNA Biology Meeting in Bethesda, MD.

APRIL

Deirdre’s News & Views on translation of endogenous circular RNAs is published in Molecular Cell. PDF

Deirdre presents her latest findings at the Penn RNP Discussion Group.

MARCH

Jiou was awarded a Summer Research Award from the Vagelos Life Sciences & Management (LSM) program to support her efforts in the lab.

Jeremy gave an invited talk at the University of Albany.

Jeremy is quoted in a news piece on circular RNAs in Science. PDF

FEBRUARY

Jeremy gives an invited talk at the Keystone Symposium on Protein-RNA Interactions in Banff, Canada.

Chuan and Mike present talks at the Biochemistry & Biophysics Friday Research Discussions series.

Undergraduate Jiou Choi joins the group.

JANUARY

The Wilusz lab is awarded a pilot grant from the Abramson Cancer Center to investigate how translation from non-AUG start codons is regulated.

2016

NOVEMBER

Jeremy gives an invited talk at the University of Missouri-St. Louis.

Chuan, Deirdre, and Mike present their latest work at the annual retreat of the Department of Biochemistry & Biophysics in the Poconos.

OCTOBER

Collaborative work with the Bonasio lab on mapping of novel RNA-binding regions is published in Molecular Cell.

SEPTEMBER

The Wilusz lab is awarded a MIRA grant (R35) from NIGMS.

Mike presents a talk and Deirdre presents a poster at the Cold Spring Harbor meeting on Translational Control.

AUGUST

Our review on circular RNA biogenesis mechanisms is published in RNA Biology. PDF

JULY

Collaborative work with the Cherry lab on viral RNA degradation is published in Genes & Development. PDF

Postdocs Chuan Huang and Mike Kearse join the group.

Jeremy attended the Rita Allen Foundation Scholars 40th Anniversary Plenary Gathering in Palo Alto, CA.

Jeremy gave an invited talk on circular RNAs at the Gordon Research Conference on Post-transcriptional gene regulation in Stowe, VT.

Jeremy served as an invited mentor and career panelist at the Gordon Research Seminar on Post-transcriptional gene regulation in Stowe, VT.

JUNE

Undergraduate Michael Jonathan joins the group.

MARCH

The Wilusz lab presents our latest work on circular RNAs at the Biochemistry & Biophysics Friday Research Discussion series.

FEBRUARY

Jeremy presents our collaborative work on retrotransposition mechanisms at the Penn RNP Discussion Group.

2015

DECEMBER

Jeremy gives an invited talk at BMB2015 in Kobe, Japan as part of a workshop on noncoding RNA architecture and function.

NOVEMBER

Jeremy gives an invited talk at the Institute for Genetic Medicine at Hokkaido University.

Jeremy gives an invited talk on circular RNAs at GlaxoSmithKline (GSK).

Deirdre and Marianne present posters at the annual retreat of the Department of Biochemistry & Biophysics in the Poconos.

Our collaborative paper with John Moran’s lab on how the LINE-1 poly(A) tail promotes retrotransposition is published in Molecular Cell. Press Release

OCTOBER

Marianne and Dongming’s paper showing that intronic repeats and trans-acting factors regulate circular RNA levels is published in Genes & Development. PDF

Deirdre presents a talk on non-polyadenylated mRNAs at the Penn Biomedical Postdoctoral Research Symposium.

SEPTEMBER

Our News & Views on new tRNA sequencing methods is published in Nature Methods. PDF

AUGUST

Jeremy presents a poster on circular RNAs at the Cold Spring Harbor meeting on Eukaryotic mRNA Processing.

JULY

Jeremy is named a Rita Allen Foundation Scholar. This 5 year grant will support our work on circular RNAs. Penn News Release

JUNE

Our review on the mechanisms by which long noncoding RNAs are generated, stabilized, and function is published in Biochimica et Biophysica Acta (BBA).

Graduate student Marianne Kramer joins the group.

Jeremy gives an invited talk on non-polyadenylated mRNAs at the RNA Stability Meeting in Estes Park, CO.

MAY

Undergraduate Lihi Zaks joins the group and is supported by the Penn Undergraduate Research Mentoring (PURM) Program.

Jeremy presents a poster on circular RNAs at the 20th Annual Meeting of the RNA Society in Madison, WI.

Our review on circular RNA biogenesis mechanisms is published in Mobile Genetic Elements.

APRIL

Our review on tRNA regulatory mechanisms is published in WIREs RNA.

MARCH

Jeremy gives an invited seminar at the Johns Hopkins Bloomberg School of Public Health.

Deirdre presents her latest results at a seminar for the Penn RNP Discussion Group.

FEBRUARY

The Wilusz lab celebrates its one year anniversary with a homemade cake depicting the Phanatic in a lab coat.

JANUARY

Our collaborative paper with Leemor Joshua-Tor’s lab on the mechanism of CCACCA addition is published in Cell. Press Release

2014

DECEMBER

Jeremy gives a seminar at Rutgers New Jersey Medical School.

NOVEMBER

Jeremy’s perspective on the connections between NMD and snoRNA biogenesis is published in Genes & Development.

The Wilusz lab attends the annual retreat of the Department of Biochemistry & Biophysics in the Poconos. Jeremy gives a talk on CCACCA addition.

OCTOBER

Dongming’s paper on circular RNAs is published in Genes & Development. PennMedicine Press Release

AUGUST

Jeremy attends the Cold Spring Harbor meeting on Regulatory & Noncoding RNAs and gives a talk on circular RNA biogenesis.

JUNE

Jeremy gives an invited talk at the symposium in honor of Phil Sharp’s 70th birthday.

Postdoctoral fellow Deirdre Tatomer joins the group.

Jeremy presents a poster on circular RNA biogenesis at the 19th Annual Meeting of the RNA Society in Quebec City, Quebec.

APRIL

Research specialist Dongming Liang joins the group.

FEBRUARY

Jeremy gives an invited talk at the Watson School of Biological Sciences graduate student recruitment weekend.

The Wilusz lab officially begins at the University of Pennsylvania.

 

Escape Room 2017Escape Room, August 2017

Wilusz Lab November 2016Departmental Retreat, Skytop Lodge, November 17, 2016

Phillies Game on August 4, 2016 Lab at a Phillies game, August 4, 2016

Himeji Castle

Himeji Castle, Japan

Phanatic Cake

Phillie Phanatic immortalized

Donuts

Circular donuts to celebrate circular RNAs