2024 Workshop
Multimodal Imaging of Lipid Metabolism in Health and Disease
Tuesday, March 12, 2024
BRB Gaulton Auditorium, Ground Floor BRB II Building
Perelman School of Medicine at the University of Pennsylvania
Organizing committee: Ravinder Reddy, PhD, John Detre, MD, Felix Wehrli, PhD, Walter Witschey, PhD, Arjun Yodh, PhD, Wesley Baker, PhD, Haris Mohammad, PhD, Ari Borthakur, PhD, Susan Colleluori
8:00 AM Registration and Breakfast
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8:30 AM |
Opening Remarks |
Ravinder Reddy, PhD & John Detre, MD |
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8:40 AM |
Overall Plenary: Novel Functions of Oligodendrocytes and Myelin Lipids in the Nervous System |
Klaus-Armin Nave, PhD (virtual) Max Planck Institute Natur, Goettingen |
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Moderator |
Arjun Yodh, PhD and Mohammad Haris, PhD |
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9:30 AM |
Session Plenary: Monitoring Lipid Metabolism in Cancer |
Almut Schulze, PhD (virtual) German Cancer Research Center |
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10:00 AM |
Optical Imaging of Lipid Metabolism: Applications in Fluorescence Guided Surgery |
Jim Delikatny, PhD (virtual) UPENN |
| 10:20 AM | Break | |
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10:40 AM |
Dietary control of Intestinal Stem Cells in Physiology and Disease |
Omar H. Yilmaz, PhD MIT |
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11:00 AM |
Frequency Domain Diffuse Optical Spectroscopy for In Vivo Label-free Measurement of Lipids |
Darren Roblyer, PhD Boston University |
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11:20 AM |
In vivo Fluorescent Imaging to Identify Lipid Metabolism in Breast Cancer Residual Disease and Recurrence |
Megan Madonna, PhD Duke University |
| 11:40 AM | Session Q&A |
11:50 AM - 1:00 PM Lunch
| Moderators: | Felix Wehrli, PhD and John Detre, MD | |
| 1:00 PM | Session plenary: Myelin Bilayer Mapping with MRI | Markus Weiger/Klaas Pruessmann, PhD (virtual, ETH) |
| 1:30 PM | Metabolic Reprogramming in Brain During Midlife: Implications for White Matter Lipids and Risk of Alzheimer’s Disease in Later Life | Roberta Brinton, PhD (virtual, Arizona) |
| 1:50 PM | NeuroImaging of Aging (NIA) using MR Physics to Study the Role of White Matter Determinants in Aging and Dementia | Mustapha Bouhrara, PhD (virtual, NIH) |
| 2:10 PM | What can Advanced Imaging and its Histological Correlates Teach us about Myelin Pathology? | Cornelia "Corree" Laule, PhD (UBC) |
| 2:30 PM | Lipid Sensitive MR Imaging Modalities in Preclinical Models of Alzheimer's Disease | Anshuman Swain, BS (Penn) |
| 2:50 PM | Session Q/A |
3:00 - 3:20 PM - Break
| Moderator: | Walter Witschey, PhD | |
| 3:20 PM | Session plenary: Where's the Fat? Insights from Large Scale Biobanks | Dan Rader, MD (Penn) |
| 3:50 PM | Sarcopenia and Myosteatosis as Markers of Poor Nutrition — using Imaging-derived Features of Body Composition to Screen for Increased Surgical Risk | Victoria M. Gershuni, MD (Penn) |
| 4:10 PM | Advanced Methods for Quantitative MRI of Liver Fat and Body Composition in Young Subjects and Adults | Holden Wu, PhD (UCLA) |
| 4:30 PM | Endogenous Functional MRI of the Metabolic Activation of Adipose Tissues | Kejia Cai, PhD (virtual, UI Chicago) |
| 4:50 PM | Lipomatous Metaplasia as the Substrate of VT in Ischemic Cardiomyopathy | Saman Nazarian. MD, PhD (Penn) |
| 5:10 PM | Session Q/A |
5:30 - 6:30 PM Reception, BRB Gaulton Lobby