CAMIPM Seminar Series
Title: "Electrophysiological Stratification Biomarkers for Autism Spectrum Disorder"
In person speaker:
Timothy Roberts, Ph.D., FASFNR
Vice Chair Research, Radiology
Oberkircher Family Chair in Pediatric Radiology
Children's Hospital of Philadelphia
Abstract and teaching points
This talk will introduce various potential roles for electrophysiology in general, and magnetoencephalography (MEG) in particular, for addressing pressing issues in the heterogenous developmental disorder: autism spectrum disorder, and related genetic syndromes.
1. Defining biologically-based sub-types of ASD (multi-modal MEG/MRI/MRS)
2. Related genetic syndromes (16p11.2 del/dup; 47,XYY; NF1)
3. Full spectrum – include minimally-verbal / non-verbal
4. Infant predictors of ASD and ID/DD
5. Behaviorally-motivated intervention – “Language Aid”
Time: 3:00 PM
Date: Thursday, February 16th, 2023
Location: Room 1412 BRB2
Meeting ID: 934 3573 0386
Multimodal Imaging of Ketone Body Metabolism in Health and Disease
Welcome to the Center For Advanced Metabolic Imaging in Precision Medicine (CAMIPM), a National Center for Biomedical Imaging and Bioengineering (NCBIB) in the Perelman School of Medicine at the University of Pennsylvania.
The CAMIPM develops and translates cutting edge noninvasive metabolic imaging biomarkers for use in biomedical research. Technology development is focused in four major application areas: Oncology, Cardiovascular disease, Neuropsychiatry, and Musculoskeletal disorders. These technologies will have substantial impact on the fundamental understanding of disease mechanisms, early diagnosis, and development of novel therapies for several diseases such as Alzheimer’s disease, Epilepsy, Arthritis, Cancer, Stroke, and heart disease, and thus contribute to precision medicine and enhanced patient care. The facility’s core sections provide research and computing resources for numerous user, collaborative, and training projects.
The focus of this center is on developing instrumentation, methodologies, and data analysis techniques for the quantitative assessment of functional, structural, and metabolic parameters in humans with the use of chemical exchange weighted molecular magnetic resonance imaging (MRI), MRI of oxygen consumption, down field spectroscopy, and diffuse optical imaging techniques.
We are supported by the NIBIB under Grant No. P41 EB029460.